Body
DALLAS, October 26, 2020 -- People with severe obesity (BMI >35) and a prior heart attack who undergo weight-reduction surgery may lower their risk of a second heart attack, major cardiovascular event, heart failure and death compared to people with similar medical histories who did not have weight-reduction surgery, according to new research published today in Circulation, the flagship journal of the American Heart Association.
Researchers at Karolinska Institutet and Danderyd Hospital in Sweden have studied the risk of additional myocardial infarctions and early death in severely obese patients who undergo metabolic surgery following a myocardial event. The registry study covering 1,018 individuals shows a lower risk of additional myocardial infarctions and improved survival that cannot be simply attributed to the loss of weight. The study is published in the journal Circulation.
DALLAS, Oct. 26, 2020 -- At a time when stroke is on the rise among young adults, nearly 30% of U.S. adults younger than age 45 do not know all five of the most common stroke symptoms, according to new research published today in Stroke, a journal of the American Stroke Association, a division of the American Heart Association.
Highlights
Social determinants of health are associated with patient-reported outcomes in adults who are eligible to undergo kidney transplantation evaluations.
Results from the study will be presented online during ASN Kidney Week 2020 Reimagined October 19-October 25.
Washington, DC (October 25, 2020) -- Certain social determinants of health predict patient-reported outcomes in potential kidney transplant recipients, according to a study that will be presented online during ASN Kidney Week 2020 Reimagined October 19-October 25.
Not all pregnant women are universally screened for hepatitis B virus (HBV) in Ontario, even though this screening is recommended, and the majority of those who test positive do not receive follow-up testing or interventions, leading to infections of newborns, found new research in CMAJ (Canadian Medical Association Journal).
An estimated 257 million people worldwide are chronically infected with HBV, which is a risk for cirrhosis of the liver and liver cancer.
Highlights
In a recent study, a new algorithm achieved good performance for predicting which hospitalized patients will develop acute kidney injury requiring dialysis.
Results from the study will be presented online during ASN Kidney Week 2020 Reimagined October 19-October 25.
Indian and Pakistani women are diagnosed with breast cancer, including more aggressive forms of the disease, at a younger age, according to Rutgers researchers.
South Asians are the fastest-growing major ethnic group in the United States with breast cancer rates increasing within the population, but little is known about the disease in this socio-culturally unique population.
A novel agent that targets a mutated form of the KRAS gene - the most commonly altered oncogene in human cancers and one long considered "undruggable" - shrank tumors in most patients in a clinical trial with manageable side effects, researchers reported today at the 32nd EORTC-NCI-AACR Symposium on Molecular Targets and Therapeutic, which is taking place online.
New results from early clinical trials of a drug that targets a cancer-causing mutation in the KRAS gene have shown that it can shrink tumours and is well-tolerated by patients.
Washington, DC (October 23, 2020) -- The results of numerous high-impact clinical trials that could affect kidney-related medical care will be presented online during ASN Kidney Week 2020 Reimagined October 19-October 25.
The findings, simultaneously published in the New England Journal of Medicine and presented at the American Society of Nephrology's Kidney Week 2020 conference, show the investigational drug finerenone had tangible renal and cardiovascular benefits for patients with chronic kidney disease and type 2 diabetes.
PHILADEPHIA--Treating lung cancer patients with proton therapy may help reduce the risk of radiation-induced heart diseases, suggests a new study from Penn Medicine. In a retrospective trial of more than 200 patients, mini-strokes were significantly less common among patients who underwent proton therapy versus conventional photon-based radiation therapy. Proton therapy patients also experienced fewer heart attacks.
Researchers at the Institut de Recerca Sant Joan de Déu (IRSJD) in collaboration with those at Centre for Genomic Regulation (CRG) have discovered that RING1B is a critical gene for the development of Ewing sarcoma, a rare type of developmental cancer that presents in bones and soft tissues. This newly uncovered epigenetic vulnerability in Ewing sarcoma cancer cells opens the door for new therapeutic strategies.
Although the lungs are a common target for COVID-19's cytokine storm, so are the kidneys, making the 1 in 4 U.S. adults with diabetes resulting in diabetic kidney disease at increased risk for virus mortality.
But why are the kidneys so attractive to the coronavirus?
People with diabetes -- especially the 20 to 40 percent with diabetic kidney disease -- are among the most at risk for serious complications and death from COVID-19. A new study of gene expression utilizing machine learning peered inside the kidney cells of COVID-19 patients and diabetic kidney disease patients and made a surprising discovery: Similar molecular processes were activated in both sets of patients, revealing potential avenues of viral vulnerability.