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To allow meaningful comparison between COVID-19 vaccine candidates and ensure that the most effective candidates are deployed, researchers working on different vaccines should collaborate and assess vaccine efficacy using standardised methods
Determining whether a vaccine can protect against severe disease and death from COVID-19 might not be possible in clinical trials, and will likely require long-term, ongoing studies after any candidate is licenced and deployed
What The Study Did: This randomized clinical trial compared the change in pain severity among adults with chronic low back pain who received electroacupuncture or a placebo treatment.
Authors: Jiang-Ti Kong, M.D., of the Stanford University School of Medicine in Stanford, California, is the corresponding author.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamanetworkopen.2020.22787)
The loss of huge ice masses can contribute to the warming that is causing this loss and further risks. A new study now quantifies this feedback by exploring long-term if-then-scenarios. If the Arctic summer sea-ice were to melt completely, a scenario that is likely to become reality at least temporarily within this century with ongoing greenhouse gas emissions from burning fossil fuels, this could eventually add roughly 0.2°C to global warming. It is, however, not in addition to IPCC projections of future warming since these already take the relevant mechanisms into account.
Researchers have improved the assessment of consistency in meta-analysis. The improved consistency measure considers statistical power, and it has potential to alter the interpretation of meta-analyses. The new measure was published in European Journal for Philosophy of Science.
Meta-analysis refers to combining results of several studies mathematically. Especially, medicine considers meta-analyses as the highest level of evidence. If a meta-analysis recommends a treatment, the treatment most probably becomes established.
The Journal of the Institute of Materia Medica, the Chinese Academy of Medical Sciences and the Chinese Pharmaceutical Association, Acta Pharmaceutica Sinica B (APSB) is a monthly journal, in English, which publishes significant original research articles, rapid communications and high quality reviews of recent advances in all areas of pharmaceutical sciences -- including pharmacology, pharmaceutics, medicinal chemistry, natural products, pharmacognosy, pharmaceutical analysis and pharmacokinetics.
Featured papers in this issue are:
Understanding the role of antibiotic use patterns and patient transfers in the emergence of drug-resistant microbes is essential to crafting effective prevention strategies, suggests a study published today in eLife.
PHILADELPHIA - Beth Reisboard, 76, was relieved in 2018 when she received the results from her annual mammogram: "Negative." But her OB-GYN suggested she have a second screening. Reisboard has dense breasts, which means there are certain cancers that mammography may not be sensitive enough to detect.
Surprised, Reisboard scheduled an appointment to undergo an abbreviated MRI at Penn Medicine. Twelve hours later, she received a call from the clinic -- they had found a tumor.
When the Universe was only a tenth of its current age its galaxies experienced a growth spurt. It was this period that the scientists in the ALPINE project (1) focused on when they used ESO's ALMA (2) telescope to carry out the first ever large survey of distant galaxies. To their surprise, these galaxies observed in the early stages of their life were far more mature than expected. Their work is the subject of a series of articles published on 27 October 2020 in the journal Astronomy & Astrophysics, signed among others by members of the CNRS and Aix-Marseille Université (3).
Empathy is talked about a lot these days. Against the backdrop of a global pandemic and a divisive political climate in the United States, calls for empathy have become louder and more urgent. We encourage empathy for those inflicted with COVID-19 and those struggling with unemployment. We reminisce about the empathy of public figures who have recently passed away. Both Democrats and Republicans have highlighted their own presidential candidate's empathy and accused the other side of lacking it.
Rye Brook, NY (Monday, October 26, 2020) - Patients participating in The Leukemia & Lymphoma Society's (LLS) groundbreaking precision medicine Beat AML Master Clinical Trial had superior outcomes compared to acute myeloid leukemia (AML) patients who opted for standard chemotherapy treatment, according to findings published today in the prestigious Nature Medicine journ
Orthopedic surgeons at Hospital for Special Surgery (HSS) performed successful microsurgery to repair damaged nerves and restore muscle strength and movement to patients experiencing paralysis from Parsonage-Turner Syndrome (PTS), according to a study published online ahead of print in The Journal of Hand Surgery.
A new study led by researchers at Queen Mary University of London provides potential novel biomarkers for predicting patient responsiveness to disease modifying anti-rheumatic drugs (DMARDs).
Rheumatoid Arthritis (RA) patients are commonly treated with disease modifying anti-rheumatic drugs (DMARDs) despite the fact that up to 50% of patients are unresponsive to treatment. Up until now, there has been no way to find out whether a patient will effectively respond to treatment.
A team of researchers from the Germans Trias i Pujol Hospital and Research Institute (IGTP) and the Hospital del Mar Medical Research Institute (IMIM) has shown that regularly consuming foods rich in omega-3 fatty acids, from both animal and vegetable origins, strengthens the heart's membranes and helps improve the prognosis in the event of a myocardial infarction.
Trust or disappointment in government crisis management is an important factor for the general mood, shows a study by the University of Zurich based on surveys in Israel and Switzerland. At the end of April, Israelis were twice as disappointed with their government institutions during the pandemic as Swiss citizens. In Switzerland, a certain fatalism made for less negative feelings.
Cancer remodels the architecture of our chromosomes so the disease can take hold and spread, researchers at the University of Virginia have revealed.
This remodeling is important because the arrangement of the components in our chromosomes actually affects the workings of our genes. With these renovations, cancer begins making a comfortable home for itself inside our cells.