Body

One consequence of the COVID-19 pandemic is that more families are putting off their children's preventive care visits, causing pediatric providers to worry about missed vaccines.

(Boston)--Obesity is associated with poor COVID-19 outcomes but a new study suggests this is not due to increased inflammation, but instead may be driven by respiratory issues or other factors.

Pregnant women are among those most in need of safe and effective therapies against COVID-19, but they are routinely excluded from the majority of clinical treatment trials, according to authors of an opinion piece based on a review of international trial registry data, published in The Lancet Global Health journal.

PROVIDENCE, R.I. [Brown University] -- For people living with opioid use disorder, the path to treatment is not always clear-cut. Sometimes, there's no path at all.

The gap between those recommended for medications for opioid use disorder -- with methadone, buprenorphine or other medications prescribed -- and those who ultimately receive it is wide and persisting. At the epicenter, accounting for more than one third of individuals with an opioid use disorder, are Medicaid recipients.

Positive results from additional analyses of PRIDE-HD and Open-HART trials with pridopidine published in peer-reviewed journal, The Journal of Huntington’s Disease.

Exploratory additional efficacy data show pridopidine (45 mg bid) to be the first drug to exert a significant and clinically meaningful beneficial effect on Total Functional Capacity (TFC).

Results from Open-HART trial demonstrate potential durability of the effect of pridopidine with less TFC decline over 5 years compared to historical placebo group, as well as positive safety and tolerability data.

BOSTON -- Understanding the body's immune response to SARS-CoV-2, the virus that causes COVID-19, is key to developing effective treatments and long-lasting vaccines. Of particular interest are neutralizing antibodies, which can block the virus from entering and infecting human cells, helping the immune system clear the virus and prevent future infections.

DES PLAINES, IL -- The LOOP technique for incision and drainage (I&D) of abscesses in adults is a safe and effective alternative to the traditional I & D with packing and may offer an alternative to the standard regimen in the treatment of uncomplicated skin abscesses in pediatric patients. That is the conclusion of a study to be published in the December 2020 issue of Academic Emergency Medicine (AEM), a journal of the Society for Academic Emergency Medicine (SAEM).

Companies worldwide are facing unprecedented challenges due to the COVID-19 pandemic, from modifying operations to keeping employees safe and informed. But not all businesses have followed the recommended safety protocols set by the Centers for Disease Control and Prevention. This mixed messaging could have a significant impact on employee trust, loyalty and overall commitment, according to a study led by the University of Houston Conrad N. Hilton College of Hotel and Restaurant Management and Missouri State University's Hospitality Leadership Department.

WASHINGTON, DC - DEC. 16, 2020 -- As the biggest vaccination effort in U.S. history gets underway, several states may not have a sufficient number of facilities in some areas to administer the COVID-19 vaccine to all residents who want it, according to a new analysis from the University of Pittsburgh School of Pharmacy and the nonprofit West Health Policy Center.

When taken daily, pre-exposure prophylaxis, or PrEP, is a highly effective way to prevent HIV transmission, according to the Centers for Disease Control and Prevention. Now a new study shows that implementing PrEP distribution within a community-based syringe services program gets the medication into the hands of women who inject drugs -- a population disproportionately impacted by HIV.

PISCATAWAY, NJ - When college campuses closed in the spring due to the COVID-19 pandemic, the quantity of alcohol consumed by students decreased significantly if they went from living with peers to living with parents, according to a new report in the Journal of Studies on Alcohol and Drugs.

December 16, 2020, OAKLAND, Calif. -- Kaiser Permanente physicians and therapists now have the ability to refer their patients to evidenced-based mental health and wellness apps through the organization's electronic health record system. With a simple referral to an app, Kaiser Permanente patients can begin using it on their own or under the guidance of a clinician -- at no cost.

BOSTON - (December 02, 2020) - A lipid metabolite called 12,13-diHOME is in human breast milk and appears to be associated with beneficial infant weight gain and body composition in the early postnatal period. Moreover, maternal fitness, specifically exercise, appears to boost levels of the metabolite in breast milk and so might benefit their offspring. This finding was published online by The Journal of Clinical Endocrinology and Metabolism.

With only 1% difference, the human and chimpanzee protein-coding genomes are remarkably similar. Understanding the biological features that make us human is part of a fascinating and intensely debated line of research. Researchers at the SIB Swiss Institute of Bioinformatics and the University of Lausanne have developed a new approach to pinpoint, for the first time, adaptive human-specific changes in the way genes are regulated in the brain. These results open new perspectives in the study of human evolution, developmental biology and neurosciences.

Communication, serendipity and an enzyme called DOT1L have all combined to produce some exciting findings into the immune system's B cells and T cells by two groups of Monash Biomedicine Discovery Institute (BDI) scientists. These could result in further studies into a target for asthma and allergies, and fundamental work exploring the formation of immunity itself.

Two papers on DOT1L by teams led by Professor Colby Zaph and Associate Professor Kim Good-Jacobson - whose labs are next door to each other - were each published in Cell Reports today.