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ANN ARBOR, Michigan -- While many people have listened to messaging about wearing a mask and following social distancing guidelines to limit the spread of COVID-19, resistance remains. A new study finds that appealing to people's concerns for their loved ones could overcome this resistance. And it may have implications for encouraging people to get the new vaccine.
Breast cancer, the second most common cancer in the United States, can result from a number of cellular misregulations, such as deficiencies in the DNA-repairing breast cancer gene, BRCA. Typically, BRCA-associated breast cancer is treated with poly ADP ribose polymerase (PARP) inhibitors and, recently, clinical trials have investigated pairing PARP inhibitor therapy with immunotherapy. Based on preclinical data, it is expected that the combination will recruit and activate T cells -- immune cells that can kill tumor cells.
BOSTON -- The growth of prenatal screening in Europe has reduced the number of babies being born per year with Down syndrome (DS) by an average of 54%, according to a new study published in the European Journal of Human Genetics by researchers from Massachusetts General Hospital (MGH) and international Dow
LOS ANGELES -- In recent decades, the age of men who father children has increased. However some older would-be dads face a stumbling block because they have undergone vasectomies. In addition, research has shown that male fertility decreases with age.
Even the best-managed long-term care homes will need to step up to get through the second wave of the pandemic, suggests a new study by researchers at the UBC school of nursing.
CHICAGO (December 17, 2020): The current surge in coronavirus disease 2019 (COVID-19) cases poses challenges for providers and institutions in delivering care to infected patients while also placing demands on them to keep up with timely and sometimes critical care for patients with cancer, heart disease and other serious illnesses who might experience advanced complications and/or earlier death if they have lapses in their care.
Chemotherapy attacks all cells in our body and not just cancer cells, which is why patients undergoing the treatment often experience side effects such as physical weakness, hair loss and nausea. However, because cancer cells divide and spread faster than most normal cells, cancer cells are more sensitive to chemotherapy, which kills cells by inhibiting their ability to spread. Chemotherapy often targets and damages DNA so that cancer cells can no longer replicate their genome, which is the process of copying the genetic information, and stop the growth and die.
Peer-reviewed / Observational / People
Study based on French national data from 89,530 patients hospitalised with COVID-19 between 1 March and 30 April 2020 and 45,819 patients hospitalised with seasonal influenza between 1 December 2018 - 28 February 2019.
Death rate among hospitalised COVID-19 patients was three times higher than seasonal influenza (15,104/89,530 [16.9%] vs influenza 2640/45,819 [5.8%]).
Parents, caregivers and health care professionals are increasingly concerned about childhood obesity. Compounding their concern are fears of inadvertently provoking disordered eating, such as unhelpful dieting, when discussing a child’s weight status (i.e. normal weight, overweight or obese). Given the complexity of these concerns, major health advocacy groups have independently published guidelines for having conversations with children about weight status – all at the fingertips of parents, caregivers and health care professionals with a quick internet search.
BOSTON - A first-of-its-kind intervention integrating palliative care early in the course of cancer therapy for patients with advanced acute myeloid leukemia (AML), a highly aggressive cancer of the blood and bone marrow, resulted in substantial improvements in patients' quality of life, mood and end-of-life care, a team of investigators has found.
Researchers at the University of Ottawa have found the mental health effects of the COVID-19 pandemic have particularly impacted healthcare professionals and their sleep, putting these frontline workers at risk of severe future mental health problems.
Hearing loss and diabetes are major public health problems, with Latinos at higher risk than other demographic groups. In a new study published December 17, 2020 in the online issue of JAMA Otolaryngology-Head & Neck Surgery, researchers at University of California San Diego School of Medicine with colleagues elsewhere, report that hearing loss and high blood sugar are associated with poor cognitive performance among middle-aged and older Latinos.
In a new study published in the Journal of Medical Entomology, researchers at the University of Maryland (UMD) found higher rates of West Nile virus-infected mosquitoes in lower-income neighborhoods in urban areas of Baltimore, Maryland.
Researchers at the Center for Health Outcomes and Policy Research (CHOPR) at the University of Pennsylvania School of Nursing, conducting independent research on whether pending nurse staffing legislation in New York state is in the public's interest, found that the wide variation in patient-to-nurse ratios across hospitals in New York is contributing to avoidable deaths for patients with sepsis, a common, high mortality condition.
December 17, 2020 -- An opinion piece published today online in BMJ by Nina Schwalbe in the Heilbrunn Department of Population and Family Health at Columbia Mailman School of Public Health, calls for a national vaccine strategy now that COVID-19 vaccines are available. Schwalbe writes that a lack of clarity on a distribution plan sets unrealistic expectations among the public and could undermine public trust. But even with a clearly defined strategy in place, vaccinating hundreds of millions of Americans will not be easy. Read the full article here.