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Novel immunotherapy boosts long-term stroke recovery in mice
Specialized immune cells that accumulate in the brain in the days and weeks after a stroke promote neural functions in mice, pointing to a potential immunotherapy that may boost recovery after the acute injury is over, University of Pittsburgh School of Medicine neurologists found.
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Body chemistry can predict severity of depression after death of spouse
new study from researchers at Rice University has found that bodily inflammation after the death of a spouse can predict future depression.
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Nickel atoms detected in the cold gas around interstellar comet 2I/Borisov
Unbound nickel atoms and other heavy elements have been observed in very hot cosmic environments, including the atmospheres of ultra-hot exoplanets and evaporating comets that ventured too close to our Sun or other stars. A new study conducted by JU researchers reveals the presence of nickel atoms in the cold gasses surrounding the interstellar comet 2I/Borisov. The team's finding is being published in Nature on 19 May 2021.
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Fresh insight into protein production inside brain cells could help tackle Parkinson's
New research published today sheds important light on how the production of a key protein in the brain is controlled, which could pave the way for new treatments for a wide range of neurological conditions.
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Cholesterol levels sustainably lowered using base editing
Base editing is a novel gene editing approach that can precisely change individual building blocks in a DNA sequence. By installing such a point mutation in a specific gene, an international research team led by the University of Zurich has succeeded in sustainably lowering high LDL cholesterol levels in the blood of mice and macaques. This opens up the possibility of curing patients with inherited metabolic liver diseases.
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New insight into protein production in brain could help tackle dementia
A pioneering new study led by UCL scientists has revealed, for the first time, a layer of genetic material involved in controlling the production of tau; a protein which plays a critical role in serious degenerative conditions, such as Parkinson's and Alzheimer's disease.
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Good results with online CBT for atopic eczema
The common skin disease atopic eczema (AE) impacts heavily on the life quality and general health of sufferers. Researchers at Karolinska Institutet have now evaluated its treatment with internet-delivered cognitive behavioural therapy (iCBT). The study suggests that patients feel better after iCBT compared with a control group who received only traditional treatment. The results, which are published in JAMA Dermatology, might eventually make important care available to a large patient group.
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Mitochondrial function influences schizophrenia status in patients with genetic disorder
A multidisciplinary team of researchers showed how the "batteries" of cells are highly implicated in whether patients with the chromosome 22q11.2 deletion syndrome develop schizophrenia. The results of the study may eventually lead to targeted prevention and treatment strategies for patients with the condition.
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Racial/ethnic representation among departmental chairs in academic medicine
What The Study Did: Racial and ethnic representation among departmental chairs and faculty in academic medicine in the United States from 1980 to 2019 was examined in this study.
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Characteristics associated with multisystem inflammatory syndrome among adults with SARS-CoV-2
What The Study Did: Clinical characteristics and outcomes of patients with multisystem inflammatory syndrome among adults with laboratory-confirmed SARS-CoV-2 infection at a single U.S. medical center are described in this study.
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Assessing association of vitamin D level with SARS-CoV-2 seropositivity among working-age adults
What The Study Did: SARS-CoV-2 seropositivity wasn't associated with low levels of vitamin D independently of other risk factors.
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Consumer views on using digital data for COVID-19 control
What The Study Did: This study looked at the use of consumer digital information for COVID-19 control U.S. adults consider to be acceptable and the factors associated with higher or lower approval of using this information.
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Socioeconomic disadvantage, long-term outcomes after heart attack
What The Study Did: Registry data were used to examine the association between living in a socioeconomically disadvantaged area and long-term survival among patients who had their first heart attack at or before age 50.
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Racial/ethnic diversity among OBGYN, surgical, nonsurgical residents
What The Study Did: Researchers evaluated racial and ethnic diversity among obstetrics and gynecology, surgical and nonsurgical residents in the United States from 2014 to 2019.
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Study finds worse outcomes for heart attack survivors living in disadvantaged neighborhoods
Researchers found that even after adjusting for other health risk factors, neighborhood-level socioeconomic disadvantage was associated with a 57 percent higher rate of cardiovascular mortality over an approximate 11-year follow-up period.
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Heavy metal vapors unexpectedly found in comets throughout our Solar System -- and beyond
A new study by a Belgian team using data from the European Southern Observatory's Very Large Telescope has shown that iron and nickel exist in the atmospheres of comets throughout our Solar System, even those far from the Sun. A separate study by a Polish team, who also used ESO data, reported that nickel vapor is also present in the icy interstellar comet 2I/Borisov. This is the first time heavy metals have been found in the cold atmospheres of distant comets.
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Protein simulation, experiments unveil clues on origins of Parkinson's disease
Parkinson's disease is the second most common neurodegenerative disease and affects more than 10 million people around the world. To better understand the origins of the disease, researchers from Penn State College of Medicine and The Hebrew University of Jerusalem have developed an integrative approach, combining experimental and computational methods, to understand how individual proteins may form harmful aggregates, or groupings, that are known to contribute to the development of the disease.
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'Postcode lottery' of nutrient intake from crops revealed in new study
The amount of nutrients people get from the crops that they eat is a type of 'postcode lottery', according to new research that has analysed thousands of cereal grains and soils as part of a project to tackle hidden hunger in Malawi and Ethiopia.
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Mapping the quantum frontier, one layer at a time
Researchers design new experiments to map and test the mysterious quantum realm.
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Researchers estimate COVID-19-positive rate in Stockholm during first year of pandemic
By the end of the first year of the pandemic in metropolitan Stockholm, investigators estimate that one-fifth of adults in the region previously had COVID-19. The findings, which are published in the Journal of Internal Medicine, come from analyses of anti-viral antibody responses in healthy blood donors and pregnant women.
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