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From mice to men: Study reveals potential new target for treating acute myeloid leukemia

Eurekalert - May 20 2021 - 00:05
A study released in STEM CELLS indicates that blocking transforming growth factor beta 1 (TGFβ1) could improve hematopoiesis in patients with acute myeloid leukemia.
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Two complete responses and response rate of 41% for people with synovial sarcoma reported at ASCO in Adaptimmune's phase 2 SPEARHEAD-1 trial

Eurekalert - May 20 2021 - 00:05
Adaptimmune Therapeutics plc (Nasdaq:ADAP), a leader in cell therapy to treat cancer, will report initial data from its Phase 2 SPEARHEAD-1 trial, with afamitresgene autoleucel (afami-cel, formerly ADP-A2M4), at the American Society of Clinical Oncology (ASCO) congress.
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Global food, hunger challenges projected to increase mortality, disability by 2050

Eurekalert - May 20 2021 - 00:05
A new study shows that population and climate change will exacerbate the challenge of meeting nutrition and food needs over the next 30 years, especially in Africa south of the Sahara, but also that increased investment of $25.5 billion annually would more than offset the negative impacts of climate change.
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Less forest, more species

Eurekalert - May 20 2021 - 00:05
Normally, mountain forests are among the most diverse habitats in alpine regions. Yet, as a team from the Alfred Wegener Institute discovered in the Tibetan Plateau, the higher, treeless areas are home to far more species.
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Moon mission delays could increase risks from solar storms

Eurekalert - May 20 2021 - 00:05
Although patterns in the timing of moderate space weather events are known, the most extreme and dangerous events were thought to be random in their timing. This study found for the first time that extreme space weather occurs most frequently at predictable times during solar cycles, meaning space missions could be timed to avoid them.
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Technique uses fluctuations in video pixels to measure energy use of developing embryos

Eurekalert - May 20 2021 - 00:05
Researchers at the University of Plymouth have developed a cutting edge technique which enables them to instantly examine the biological traits and behaviours of developing embryos as an energy signature, rather than focusing on individual characteristics
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Oncotarget: The comprehensive genomic profiling test, GEM ExTra®

Eurekalert - May 20 2021 - 00:05
Proprietary bioinformatics, paired with comprehensive clinical curation results in reporting that defines clinically actionable, FDA-approved, and clinical trial drug options for the management of the patient's cancer.
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New tool factors effects of fossil-fuel emissions on ocean research

Eurekalert - May 20 2021 - 00:05
A newly developed tool will allow scientists to better gauge how centuries of fossil fuel emissions could be skewing the data they collect from marine environments. Researchers at the University of Alaska Fairbanks led the effort, which created a way for marine scientists to factor into their results the vast amounts of anthropogenic carbon dioxide that are being absorbed by oceans.
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Walking in their shoes: Using virtual reality to elicit empathy in healthcare providers

Eurekalert - May 20 2021 - 00:05
Research has shown empathy gives healthcare workers the ability to provide appropriate supports and make fewer mistakes. This helps increase patient satisfaction and enhance patient outcomes, resulting in better overall care. In an upcoming issue of the Journal of Medical Imaging and Radiation Sciences, published by Elsevier, multidisciplinary clinicians and researchers from Dalhousie University performed an integrative review to synthesize the findings regarding virtual reality (VR) as a pedagogical tool for eliciting empathetic behavior in medical radiation technologists (MRTs).
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Red meat intake, poor education linked to colorectal cancer

Eurekalert - May 20 2021 - 00:05
A new paper in JNCI Cancer Spectrum indicates that several non-genetic factors--including greater red meat intake, lower educational attainment, and heavier alcohol use--are associated with an increase in colorectal cancer in people under 50.
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Does correcting online falsehoods make matters worse?

Eurekalert - May 19 2021 - 00:05
Attempting to politely correct misinformation on Twitter can have negative consequences, leading to even less-accurate tweets and more toxicity from the people being corrected, according to a study co-authored by MIT scholars.
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Blocking a protein in liver cells protects against insulin resistance, fatty liver disease

Eurekalert - May 19 2021 - 00:05
A new multi-institution study led by a team of researchers at the David Geffen School of Medicine demonstrated that blocking a protein called ABCB10 in liver cells protects against high blood sugar and fatty liver disease in obese mice. Furthermore, ABCB10 activity prompted insulin resistance in human liver cells.
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Researchers identify novel approach to repair the human heart

Eurekalert - May 19 2021 - 00:05
Loyola University Chicago researchers discover a critical component for renewing the heart's molecular motor, which breaks down in heart failure.
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Study finds high-speed ferries, recreational boats are big noise polluters in SF Bay

Eurekalert - May 19 2021 - 00:05
In a new study, researchers at the Anthropocene Institute and San Francisco State University found that recreational boats and high-speed ferries contribute significant underwater noise in San Francisco Bay, a highly urbanized coastline that is increasingly becoming a stop along the migratory routes of gray and humpback whales and home to bottlenose dolphins and harbor porpoises.
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Yellowstone National Park is hotter than ever

Eurekalert - May 19 2021 - 00:05
Yellowstone National Park is famous for harsh winters but a new study shows summers are also getting harsher, with August 2016 ranking as one of the hottest summers in the last 1,250 years.
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Earthquake creates ecological opportunity

Eurekalert - May 19 2021 - 00:05
A University of Otago study has revealed how earthquake upheaval has affected New Zealand's coastal species.
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New FAST discoveries shed light on pulsars

Eurekalert - May 19 2021 - 00:05
Using the Five-hundred-meter Aperture Spherical radio Telescope (FAST), a research team led by Prof. HAN Jinlin from National Astronomical Observatories of Chinese Academy of Sciences (NAOC) has discovered 201 pulsars, including many very faint pulsars, 40 millisecond pulsars (MSPs), and 16 pulsars in binaries.
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New pan-European research reveals double the concern about mental health impact of Lockdown and associated restrictions than physical inactivity

Eurekalert - May 19 2021 - 00:05
A new pan-European survey funded by the Institute for Scientific Information on Coffee (ISIC) exploring the impact of COVID-19 Lockdowns and associated restrictions (in those countries where there has been no Lockdown), has found that nearly two thirds of adults (61%) expressed concern about their worsening mood; two times higher than those concerned about physical inactivity (24%).
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A rapid antigen test for SARS-CoV-2 in saliva

Eurekalert - May 19 2021 - 00:05
Scientists from Hokkaido University have shown that an antigen-based test for quantifying SARS-CoV-2 in saliva samples is simple, rapid, and more conducive for mass-screening.
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Metabolic inhibitor IACS-6274 shows early antitumor effects in underserved patients

Eurekalert - May 19 2021 - 00:05
A metabolic inhibitor drug, IACS-6274, developed by MD Anderson's Therapeutics Discovery division, is well-tolerated and showed early signs of anti-tumor activity in a Phase I trial being presented at the 2021 ASCO Annual Meeting.
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