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A combination of two drugs that target different proteins on immune system T cells kept advanced melanoma in check significantly longer than one of the drugs alone in a phase 3 clinical trial involving 714 patients. Dana-Farber Cancer Institute investigators co-led the study.

The Paleozoic era culminated 251.9 million years ago in the most severe mass extinction recorded in the geologic record. Known as the "great dying," this event saw the loss of up to 96% of all marine species and around 70% of terrestrial species, including plants and insects.

Women's ability to work as entrepreneurs can help alleviate poverty and malnutrition in developing countries. As local governments and development organizations aim to encourage business opportunities, it's important to identify projects suited for women's lives in rural households.

High-end wireless and cellular networks rely on light for the distribution of signals. The selective processing of such signals requires long delays: too long to support on a chip using light alone. A research team from Bar-Ilan University, Israel, and collaborators brought together light and ultrasonic waves to realize ultra-narrow filters of microwave signals, in silicon integrated circuits. The concept allows large freedom for filters design.

For patients with severe arthritis of the ankle, total ankle arthroplasty (TAA) provides better long-term function than ankle arthrodesis (AA), reports a study in The Journal of Bone & Joint Surgery. The journal is published in the Lippincott portfolio in partnership with Wolters Kluwer.

Despite expert recommendations that children continue to get regularly scheduled vaccines during the pandemic, vaccination rates have decreased in several states.

Scanning technology aimed at detecting small amounts of nuclear materials was unveiled by scientists in Sweden today, with the hope of preventing acts of nuclear terrorism.

In new research, Texas A&M University scientists have for the first time revealed a single microscopic defect called a "twin" in a soft-block copolymer using an advanced electron microscopy technique. This defect may be exploited in the future to create materials with novel acoustic and photonic properties.

The population of white sharks that call the Central California coast their primary home is holding steady at about 300 animals and shows some signs of growth, a new long-term study of the species has shown.

If a pet owner is on a special diet, chances are their dog is too, new University of Guelph research reveals. The international survey found 21 per cent of owners prefer grain-free diets -- despite warnings that grain-free food may be linked to a dangerous heart condition in dogs.

Sexual attraction triggers change throughout our life cycles and while men and women both look for personalities indicating openess as they get older, their preferences differ in many other areas according a new study. Researchers analysed data from more than 7000 people aged between 18 and 65 who participated in the Australian Sex Survey in 2016 to track the factors driving sexual attraction throughout a person's life.

Ecologist from Freiburg investigates pest infestation in forests with mixed and monoculture tree stands.

In a study published earlier this month in Science, researchers uncover what one co-author describes as "the weirdest sex chromosome system known to science": an unassuming vole species whose X and Y chromosomes have fused, switched roles and swapped smaller pieces of DNA. The discovery is a rare exception to mammals' remarkably stable sex determination system.

The Children's Tumor Foundation (CTF) today announced the publication of updated diagnostic criteria for the genetic disorder neurofibromatosis type 1 (NF1) in Genetics in Medicine, the official journal of the American College of Medical Genetics and Genomics. The new publication is the result of an extensive, multi-year collaborative effort of over 90 leading neurofibromatosis (NF) experts from around the globe, and is aimed at improving the accuracy and earlier diagnosis of NF1 in patients.

For the first time, Cornell University researchers have developed a technique for studying the neuroscience of motor control in mice ¬- by focusing on a mouse's tongue when it licks a water spout.

Scientists at SPECIFIC Innovation and Knowledge Centre, Swansea University, have found a way to replace the toxic, unsustainable solvents currently needed to make the next generation of solar technology - printed carbon perovskite solar cells.

Florida State University researchers have more insight into salps -- a strange sea creature found in oceans around the world -- and what their presence means for the health of a marine ecosystem.

Deep pools below waterfalls are popular recreational swimming spots, but sometimes they can be partially or completely filled with sediment. New research showed how and why pools at the base of waterfalls, known as plunge pools, go through natural cycles of sediment fill and evacuation.

By mapping its genetic underpinnings, researchers at University of California San Diego School of Medicine have identified a predictive causal role for specific cell types in type 1 diabetes, a condition that affects more than 1.6 million Americans.

For the first time, geological records have been used to reconstruct the history of Larsen C Ice Shelf in Antarctica. The ice shelf is the largest remaining remnant of a much more extensive area of ice on the Antarctic Peninsula that began to break up during the 1990s (Larsen A), and saw a huge collapse in 2002 (Larsen B). This new reconstruction enables scientists to better understand if and when the remaining ice shelf could collapse in the future.