Culture

EORTC led intergroup trial investigates Imatinib failure-free survival in patients with GIST

Interim results of an EORTC intergroup trial have confirmed that adjuvant imatinib impacts short-term freedom from relapse in patients with localized, surgically resected, high/ intermediate-risk GIST. In the high-risk subgroup, a non-statistically significant trend in favor of the adjuvant arm was observed in terms of Imatinib failure-free survival.

More deaths from surgery closer to the weekend

Patients undergoing planned surgery appear more likely to die if they have their operation at the end of the week, a study published in the British Medical Journal has found.

Immigration status affects educational achievement

Mexican American mothers' formal immigration status affects the educational achievement of their children and even their grandchildren, according to a study written by Penn State and University of California, Irvine, sociologists and released by the US2010 Project at Brown University. Based on a large-scale survey of second-generation Mexican young adults in Los Angeles, the study finds that those whose mothers were authorized immigrants or U.S. citizens averaged more than two years more schooling than those whose mothers entered the country illegally.

Psychotherapy's benefits for depression

Treatments for depression that don't involve antidepressant drugs but rather focus on different forms of talking therapy (referred to as psychotherapeutic interventions) are all beneficial, with no one form of therapy being better than the others, according to a study by international researchers published in this week's PLOS Medicine.

These findings are important as they suggest that patients with depression should discuss different forms of non-drug therapy with their doctors and explore which type of psychotherapy best suits them.

Simple 'frailty' test predicts death, hospitalization for kidney dialysis patients

Johns Hopkins scientists report that a 10-minute test for "frailty" first designed to predict whether the elderly can withstand surgery and other physical stress could be useful in assessing the increased risk of death and frequent hospitalization among kidney dialysis patients of any age.

Disabled patients who can't afford their meds come to the ER more

WASHINGTON — Disabled Medicare patients under the age of 65 who don't take their prescription medications because of cost concerns are more likely to have at least one emergency department visit during a one-year period. The results of a new study are published online today in Annals of Emergency Medicine ("The Relationship Between Emergency Department Use and Cost-Related Medication Nonadherence Among Medicare Beneficiaries").

Research highlights the increasing problem of prescription drug abuse among youth

Young people are increasingly turning to prescription drugs to get high. Research out of the University of Cincinnati sheds new light on what could increase or lower that risk.

The research by Keith King, a University of Cincinnati professor of health promotion; Rebecca Vidourek, a UC assistant professor of health promotion; and Ashley Merianos, a graduate assistant in health promotion, is published in the current issue of the Journal of Primary Prevention.

For pundits, it's better to be confident than correct

PULLMAN, Wash. - It would be nice to think the pundits we see yelling on TV and squawking on Twitter are right all the time. It turns out they're wrong more often than they are right.

Now two Washington State University economics students have demonstrated that it simply doesn't pay as much for a pundit to be accurate as it does to be confident. It's one thing to be a good pundit, but another to be popular.

Decision-making preferences among patients with heart attacks

In a research letter, Harlan M. Krumholz, M.D., S.M., from Yale University School of Medicine and colleagues, "sought to investigate preferences for participation in the decision-making process among individuals hospitalized with an acute myocardial infarction ([AMI] or heart attack)." The researchers combined data from two similar AMI registries (TRIUMPH and PREMIER) which resulted in 6,636 patients in the study sample who were asked about who should make decisions on treatment options.

Reproductive Health Matters announces publication of its latest themed issue

London, May 27, 2013 - Young people are demanding information and education about their bodies, sex, their sexuality and sexual health, as well as access to services that will support them to stay safe and healthy. Papers published in the latest themed issue of Reproductive Health Matters (RHM) demonstrate that information and services in fact remain unavailable to many young people, and many may grow up without fully understanding things that they are currently experiencing such as menstruation, let alone preparing themselves for future sexual relationships and adulthood.

Engineered stem cell advance points toward treatment for ALS

MADISON, Wis. — Transplantation of human stem cells in an experiment conducted at the University of Wisconsin-Madison improved survival and muscle function in rats used to model ALS, a nerve disease that destroys nerve control of muscles, causing death by respiratory failure.

ALS (amyotrophic lateral sclerosis) is sometimes called "Lou Gehrig's disease." According to the ALS Association, the condition strikes about 5,600 Americans each year. Only about half of patients are alive three years after diagnosis.

Transparency is the Key to Higher Quality and Cost Control Post Obamacare

The Affordable Care Act (ACA) is the law of the land but it has promised a lot - higher quality, lower prices and government-run. Will it be able to do all that?

Health care reform advocates are now tasked with going from being part of the outside advocacy groups and more towards part of a solution, but Bob Kocher, MD, and Ezekiel Emanuel, MD, PhD, are still advocating. Now they want a "transparency imperative" to achieve higher quality and cost control under the new health care system.

Patients with end-stage kidney disease have different expectations than their doctors

BOSTON – In any given year, 400,000 Americans suffering from end-stage kidney disease will undergo dialysis, and as many as 20 to 25 percent of those dialysis patients will die, a statistic comparable to many types of cancer.

When doctors and patients share in decisions, hospital costs go up

Since the 1980s, doctors and patients have been encouraged to share decision making. Proponents argue that this approach promotes doctor-patient communication, enhances patient satisfaction, improves health outcomes, and even may lower cost.

Yet, a hospital-based study found that patients who want to participate in their medical decisions end up spending more time in the hospital and raising costs of their hospital stay by an average of $865.

Communication between physicians and patients important for expectations

Seriously ill patients undergoing hemodialysis are more optimistic about their prognosis and prospects for transplants than their nephrologists, according to a study published online by JAMA Internal Medicine. The study also found that nephrologists rarely had discussed estimates of life-expectancy with their patients.