Contrary to a widely-held assumption about heterosexual transmission of HIV, the normal mucosal lining of the female genital tract is not a foolproof barrier to viral penetration, scientists at the Northwestern University School of Medicine in Chicago report at the American Society for Cell Biology (ASCB) 48th Annual Meeting, Dec. 13-17, 2008 in San Francisco.
"This is an unexpected and important result," says Thomas Hope of Northwestern, "because it is generally believed that the squamous epithelium of the female genital tract is an efficient barrier to viral penetration."