Body

Duke Medicine researchers have shown how gene mutations may cause common forms of cartilage tumors.

In a study published in the Feb. 16, 2015, issue of the Proceedings of the National Academy of Sciences, Duke researchers and their colleagues revealed that mutations in the isocitrate dehydrogenase (IDH) gene contribute to the formation of benign tumors in cartilage that can be a precursor to malignancies.

It's a firmly established fact straight from Biology 101: Traits such as eye color and height are passed from one generation to the next through the parents' DNA.

A new study found that a slight regulation in the length of primary cilia, small hair-like projections found on most cells, prevented the production of fat cells from human stem cells taken from adult bone marrow.

Cells lining the intestinal tract form a critical barrier, protecting our bodies from the billions of bacteria living in the gut. Breaches in this barrier are driven largely by a single signaling molecule called tumor necrosis factor (TNF), elevated amounts of which are associated with inflammatory bowel diseases like Crohn's disease and ulcerative colitis.

Performance enhancing or doping substances such as anabolic steroids and erythropoietin, a hormone that enhances the production of red blood cells and increases oxygen consumption in the body, are no longer confined to the realm of competitive sports and increasingly now used by the mainstream.

It's about sustenance, not pleasure. Penguins can't enjoy or even detect the savory taste of the fish they eat or the sweet taste of fruit. A new analysis of the genetic evidence reported in the Cell Press journal Current Biology on February 16 suggests that the flightless, waddling birds have lost three of the five basic tastes over evolutionary time. For them, it appears, food comes in only two flavors: salty and sour.

Many other birds, such as chickens and finches, can't taste sweet things either. But they do have receptors for detecting bitter and umami (or meaty) flavors.

Frequent menopausal vasomotor symptoms (VMS), including hot flashes and night sweats, lasted for more than seven years during the transition to menopause for more than half of the women in a large study and African American women reported the longest total VMS duration, according to a new study.

VMS are the hallmark of the menopausal transition and they can affect the quality of women's lives. Up to 80 percent of women experience VMS during the transition to menopause and, despite the pervasiveness of these symptoms, robust estimates about how long VMS last are lacking.

A new family of bacteria that are common in malaria mosquitoes has been described by researchers at Swedish University of Agricultural Sciences (SLU) and Uppsala University in Sweden, Justus-Liebig-Universität Giessen, Germany, and the Veterinärmedizinische Universität, Austria. Now, attempts are made to use these bacteria in the fight against malaria.

Scientists and engineers have looked to nature for their inspiration for centuries. The field of biomimetics uses ideas from nature to solve complex human challenges.

Researchers at the Medical College of Wisconsin (MCW), in collaboration with other colleagues of the Genetic Epidemiology of Lung Cancer Consortium (GELCC), have identified a gene that is associated with lung cancer.

The findings are published in American Journal of Human Genetics. Through whole exome sequencing, researchers identified a link between a mutation in PARK2, a gene associated with early-onset Parkinson's disease, and familial lung cancer.

Recent studies have shown that added sugars, particularly those containing fructose, are a principal driver of diabetes and pre-diabetes, even more so than other carbohydrates. Clinical experts writing in Mayo Clinic Proceedings challenge current dietary guidelines that allow up to 25% of total daily calories as added sugars, and propose drastic reductions in the amount of added sugar, and especially added fructose, people consume.

Latching onto the probiotics diet fad, several studies have claimed that the gut microbiome, the diverse array of bacteria that live in the stomach and intestines, may be to blame for obesity. But Katherine Pollard, PhD, a senior investigator at the Gladstone Institutes, says it is not that simple.

A study published by researchers from Nationwide Children's Hospital, found 10 percent of adolescents sent to a Sleep Center for evaluation of excessive daytime sleepiness with testing results consistent with narcolepsy had urine drug screens positive for marijuana, confounding the results.

Nova Southeastern University (NSU) researchers recently discovered that, contrary to prior belief, tissues of different mammalian organs have very different abilities to repair damage to their DNA.

These new findings indicate that the heart has the greatest capacity to repair its DNA, followed by the intestines, kidneys, spleen, testes, and lungs. The brain, however, exhibited no ability to repair damage to its DNA.

UK commuters spend an average of about 1.5 hours a day at the wheel. Road vehicles in particular are known to emit polluting nanoparticles which contribute to respiratory and heart diseases. Now, researchers at the University of Surrey have found that where drivers spend just 2% of their journey time passing through traffic intersections managed by lights, this short duration contributes to about 25% of total exposure to these harmful particles.