Body

Interferon not beneficial for most stage III melanoma

LOUISVILLE, Ky. - Final results for the Sunbelt Melanoma Trial, published online this month in the Journal of Clinical Oncology, show that thanks to current diagnostic techniques, most stage III melanoma patients do not benefit from treatment with interferon. Kelly McMasters, M.D., Ph.D., the Ben A. Reid, Sr., M.D. Professor and Chair of the Hiram C. Polk, Jr., M.D. Department of Surgery at the University of Louisville, was the principal investigator and initiated the trial.

Hypertensive women with physically demanding jobs at 3 times risk of heart disease

Sophia Antipolis, 15 February 2016: Hypertensive women with highly active jobs have a nearly three times higher risk of ischaemic heart disease than women with normal blood pressure and moderately active jobs, according to research published today in the European Journal of Preventive Cardiology.1

New appreciation for human microbiome leads to greater understanding of human health

University of Oklahoma anthropologists are studying the ancient and modern human microbiome and the role it plays in human health and disease. By applying genomic and proteomic sequencing technologies to ancient human microbiomes, such as coprolites and dental calculus, as well as to contemporary microbiomes in traditional and industrialized societies, OU researchers are advancing the understanding of the evolutionary history of our microbial self and its impact on human health today.

Speech disorder called apraxia can progress to neurodegenerative disease

ROCHESTER, Minn. - It may start with a simple word you can't pronounce. Your tongue and lips stumble, and gibberish comes out.

Misspeaking might draw a chuckle from family and friends. But, then, it keeps happening. Progressively, more and more speech is lost. Some patients eventually become mute from primary progressive apraxia of speech, a disorder related to degenerative neurologic disease.

What values are important to scientists?

WASHINGTON, D.C. - While many people are marking today scrutinizing the virtues of their Valentines, Michigan State University revealed a first-of-its-kind study on the virtues and values of scientists.

The study, presented at the meeting of the American Association for the Advancement of Science in Washington, D.C., surveyed nearly 500 astronomers, biologists, chemists, physicists and earth scientists to identify the core traits of exemplary scientists.

Stan Riddell, Fred Hutch cancer immunotherapy innovator, to present at AAAS Annual Meeting

(SEATTLE) - Dr. Stanley Riddell, an immunotherapy researcher and oncologist at Seattle's Fred Hutchinson Cancer Research Center, on Feb. 14 will present an update on new adoptive T-cell strategies for cancer at the annual meeting of the American Association for the Advancement of Science in Washington, D.C.

Progress in fighting cancer and infections with T cell therapy

The quest to bring immunotherapy into widespread clinical use against cancer and infectious diseases has made great strides in recent years. For example, clinical trials of adoptive T cell therapy are yielding highly promising results. The latest progress is being reported at the Annual Meeting of the American Association for the Advancement of Science (AAAS 2016) by three international leaders in the field: Prof. Dirk Busch of the Technical University of Munich (TUM), Prof. Chiara Bonini of the San Raffaele Scientific Institute, and Prof.

Science responds to globalized disease threat to farms and food systems

Farmers and consumers around the world are connected and dependent on each other today in a way that is unprecedented in human history - the average chocolate bar will have ingredients from four or more continents and crop failures in Russia affect the price of bread in the US.

Transnational research collaboration between the US and UK is anticipating and protecting our food supplies from a host of new disease threats to crops, animals and humans and which show no respect for international borders.

Kenneth Miller reviews Dover model of standing up for science

PROVIDENCE, R.I. [Brown University] -- In a Harrisburg, Pa., Federal courtroom 11 years ago, Brown University biologist Kenneth Miller was the first witness in a historic takedown of Intelligent Design's pretense of scientific relevance. In the context of ongoing culture wars over evolution, climate change, stem cell research and vaccination, Miller will reunite with figures from the Kitzmiller v. Dover trial to review that trial's lessons at the annual meeting of the American Association for the Advancement of Science in Washington, D.C., Feb. 13, 2016.

Eating breakfast could help obese people get more active

Eating breakfast causes obese people to be more active, according to the latest research published from researchers at the University of Bath (UK).

The study, from health scientists based within the University's Department for Health and published in the leading diet and nutrition journal the American Journal of Clinical Nutrition, analysed the links between breakfast and health for individuals classed as 'obese', comparing the results from a fasting group with a breakfasting group.

'Jaws' may help humans grow new teeth, shark study suggests

  • Study identifies network of genes that help sharks grow new teeth throughout their lifetime
  • Humans possess same cells but tooth regeneration ability is limited
  • Research paves the way for development of therapies for human tooth loss

A new insight into how sharks regenerate their teeth, which may pave the way for the development of therapies to help humans with tooth loss, has been discovered by scientists at the University of Sheffield.

For a special Valentine? Beyond diamonds and gems: The world's rarest minerals

Scientists have inventoried and categorized all of Earth's rare mineral species described to date, each sampled from five or fewer sites around the globe. Individually, several of the species have a known supply worldwide smaller than a sugar cube.

A new form of frozen water?

Lincoln, Neb., Feb. 12, 2016 -- Amid the season known for transforming Nebraska into an outdoor ice rink, a University of Nebraska-Lincoln-led research team has predicted a new molecular form of the slippery stuff that even Mother Nature has never borne.

The proposed ice, which the researchers describe in a Feb. 12, 2016 study in the journal Science Advances, would be about 25 percent less dense than a record-low form synthesized by a European team in 2014.

From huts to cities: Changes in dwellings impact microbe exposure for human immune system

The shift from living in jungle huts to cities has dramatically changed human exposure to certain microbes, which could have implications for healthy immune function, according to a study led by researchers from NYU Langone Medical Center and published online Feb. 12, 2016 in Science Advances.

An engineer's valentine to children

BROOKLYN, N.Y. -- What better way to celebrate Valentine's Day than help save a child's heart? That's what Vittoria Flamini, an industry assistant professor in Tandon's Department of Mechanical and Aerospace Engineering, has in mind.

Children born with a certain congenital heart defect often need a percutaneous pulmonary valve surgically inserted when they are 10 to 15 years old. Flamini has developed computer simulations to determine if that surgery will be successful and if the necessary valve will fit in the individual's heart -- before the surgery takes place.