(Boston)--For the first time, researchers at Boston University have shown that T-cell leukemia cells use a particular cycle, called the TCA or Kreb cycle, to support their growth and survival.
The findings from Dr. Hui Feng and her postdoctoral trainees (Dr. Nicole M. Anderson, Dr. Dun Li, and Dr. Fabrice Laroche), which appear online in the journal Leukemia, may lead to the development of therapeutics to effectively kill these types of tumor cells by targeting a critical enzyme called DLST that exists in the TCA cycle.