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When in-store digital displays drive sales -- and when they don't

Consumers shop at different size stores for different reasons, and retailers may well wonder whether in-store digital displays for their establishments are worth the investment. New data from a study of Swedish stores can provide valuable guidance.

Epidemiologic Reviews devotes special issue to research on gun violence

The journal Epidemiologic Reviews, a leading review journal in public health, today released a special issue of the journal focused entirely on gun violence prevention and policy research. Many of the nation's top academics in gun violence research are authors of the nine different review articles included in the special issue, which cover topics ranging from the relationship between firearm access and violence to the relationship between substance abuse and gun violence.

Nearly all US forests threatened by drought, climate change

DURHAM, N.C. -- Forests nationwide are feeling the heat from increasing drought and climate change, according to a new study by scientists from 14 research institutions.

"Over the last two decades, warming temperatures and variable precipitation have increased the severity of forest droughts across much of the continental United States," said James S. Clark, lead author of the study and Nicholas Professor of Environmental Science at Duke University.

Increasing drought threatens almost all US forests

Forests nationwide are feeling the heat from increasing drought and climate change, according to a new study by scientists from 14 research institutions.

"Over the last two decades, warming temperatures and variable precipitation have increased the severity of forest droughts across much of the continental United States," said James Clark, lead author of the study and an environmental scientist at Duke University.

Clark and colleagues published their paper today in the journal Global Change Biology.

FDA-approved ALK IHC CDx superior to another IHC assay for patient selection

DENVER - The U.S. Food and Drug Administration (FDA) approved VENTANA anti-ALK(D5F3)CDx performed more accurately than another commonly used immunohistochemistry (IHC) assay, based on the use of the 5A4 clone, for the selection of patients eligible to receive ALK tyrosine kinase inhibitor (TKI) treatment.

A new way of fighting bacteria?

In bacteria, toxin-antitoxin systems consist of a set of two closely linked genes. Situated on the same chromosome, they encode both a protein 'poison' and a counteracting 'antidote'. Under normal conditions, the antitoxin protein binds the toxin protein and prevents it from acting. But in response to environmental stress, the antitoxin proteins are broken down, which allows the toxins to poison the cells.

Charlie Sheen's HIV disclosure may reinvigorate awareness, prevention of HIV

Actor Charlie Sheen's public disclosure in November 2015 that he has the human immunodeficiency virus (HIV) corresponded with the greatest number of HIV-related Google searches ever recorded in the United States, according to an article published online by JAMA Internal Medicine.

John W. Ayers, Ph.D., M.A., of San Diego State University, California, and coauthors used news and Internet searches to examine engagement with HIV-related topics around the time of Sheen's Nov. 17 disclosure.

Home health care, post-acute care in a facility infrequent for hospitalized kids

Hospitalized children infrequently used home health care (HHC) and facility-based post-acute care (PAC) after they were discharged, according to an article published online by JAMA Pediatrics. Jay G. Berry, M.D., M.P.H., of Harvard Medical School, Boston, and coauthors looked at the national prevalence of children discharged to HHC and PAC, as well as the characteristics of those children. The authors analyzed more than 2.4 million acute care hospital discharges in 2012 for patients 21 and younger from the Agency for Healthcare Research and Quality Kids' Inpatient Database.

Newly discovered HIV genome modification may put a twist on vaccine and drug design

Researchers at University of California, San Diego School of Medicine have discovered that HIV infection of human immune cells triggers a massive increase in methylation, a chemical modification, to both human and viral RNA, aiding replication of the virus. The study, published February 22, 2016 in Nature Microbiology, identifies a new mechanism for controlling HIV replication and its interaction with the host immune system.

UEA scientists pave way for new generation of superbug drugs

UEA scientists pave way for new generation of superbug drugs

Scientists at the University of East Anglia are getting closer to solving the problem of antibiotic resistance.

New research published today in the journal Nature reveals the mechanism by which drug-resistant bacterial cells maintain a defensive barrier.

The findings pave the way for a new wave of drugs that kill superbugs by bringing down their defensive walls rather than attacking the bacteria itself. It means that in future, bacteria may not develop drug-resistance at all.

Researchers trace peanut crop back to its Bolivian roots

Athens, Ga. - Researchers at the University of Georgia, working with the International Peanut Genome Initiative, have discovered that a wild plant from Bolivia is a "living relic" of the prehistoric origins of the cultivated peanut species.

The peanut that is grown by farmers today is the result of hybridization between two wild species. The hybrid was cultivated by ancient inhabitants of South America and, by selection, was transformed into today's crop plant.

TSRI researchers uncover potential target for treating autoimmune disease

LA JOLLA, CA - February 22, 2016 - Scientists from The Scripps Research Institute (TSRI) have identified a molecule that appears to be a cause of autoimmune diseases such as lupus. Elevated levels of the molecule allow self-reactive immune cells to escape into the blood stream and attack the body's own tissues.

"This is a good target for future therapies," said TSRI Associate Professor Changchun Xiao, who was co-senior author of the study with TSRI Professor David Nemazee. "We now know that this is causative--it's not just a side effect."

Crafting a better T cell for immunotherapy

T-cell therapy, a form of immunotherapy that uses a patient's own immune cells to attack their cancer, has been making waves recently. The "living" therapy involves engineering the patient's T cells in the laboratory to carry new proteins that guide the immune cells directly to tumor cells, allowing the engineered T cells to attack and kill the cancer.

Prediction: High death rates from unnatural causes for male lions in Cecil the Lion's park

When Cecil the Lion was killed last year by a trophy hunter in Zimbabwe, it caused an international outcry. Now researchers from the Universities of Southern Denmark and Oxford have calculated that many more males from the same park are likely to die in conflicts with humans.

Cecil the Lion lived in the national park Hwange in Zimbabwe. One day he wandered out of the park - though some claim that he was lured out by his killer, a trophy-hunting dentist from the USA.

Carnegie Mellon, Stanford researchers devise method to safely share password data

PITTSBURGH--An unfortunate reality for cybersecurity researchers is that real-world data for their research too often comes via a security breach. Now computer scientists have devised a way to let organizations share statistics about their users' passwords without putting those same customers at risk of being hacked.

The work at Carnegie Mellon University and Stanford University, part of an emerging field on rigorous human authentication, persuaded Yahoo! to publicly share password frequency statistics for about 70 million of its users.