Body

Scientists of the Tomsk State University have found preserved moose in Western Siberia that have unique features of DNA structure. This discovery of Tomsk scientists will help determine the origin and path of moose movement in the last few tens of thousands of years and gives reason to believe that Siberia is a unique genetic repository. The research has been presented at International Conference "Theriofauna of Russia and adjacent territories" (X Congress of Russian Theriological Society).

A University of Colorado Cancer Center study published today in the Journal of Clinical Investigation shows a weak link in the chain of events that causes an aggressive subtype of acute myeloid leukemia (AML). The study also suggests a possible tool to break this link.

Our innate immune system, made up mainly of phagocytes, protects our body by exterminating bacteria. To do this, it uses two mechanisms. The first kills foreign bodies within the phagocyte itself. The second kills them outside the cell. These two strategies were already known to researchers, but only in humans and other higher animals. Microbiologists from the University of Geneva (UNIGE), Switzerland, have just discovered that a social amoeba, a unicellular microorganism living in the soils of temperate forests, also uses both these mechanisms, and has done so for over a billion years.

- The amount of information that a genome researcher creates and which makes the basis of his scientific work has grown a million times during the last two decades. Today, the challenge does not consist in creating the data, but in exploring them and deducing meaningful conclusions. We believe that this analytical tool, which we have called "EaSeq" can help researchers in doing so, says Associate Professor Klaus Hansen

ChIP sequencing - an insight into the workflow of human cells

CHARLOTTESVILLE, VA (MARCH 1, 2016). Myelomeningocele is a neural tube defect affecting many systems in the human body and requiring multidisciplinary medical care to ensure optimal function and quality of life as well as survival of the patient. In the early 1950s survival of children born with this defect was only about 10%. Since that time advances in pediatric care have led to many patients surviving into adulthood. These patients' medical needs are best served by high-volume medical centers, according to a new article by Dr.

MIAMI, March 1, 2016-- A study by J. William Harbour, M.D., associate director for Basic Research and leader of the Eye Cancer Site Disease Group at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, and colleagues published today in Clinical Cancer Research details the discovery of a biomarker that puts patients at a higher risk for metastasis of uveal melanoma.

African American adolescents who experience high levels of racial discrimination show cellular wear and tear, according to new research published in Psychological Science, a journal of the Association for Psychological Science. The research indicated that a supportive family environment may protect against these negative physiological effects.

Researchers from University College London estimate that use of e-cigarettes produced 16K-22K additional long-term quitters in England in 2014.1 A long-term quitter is someone who has not smoked for at least one year.

BOSTON -- If you're a lung or colorectal cancer patient, what's in your wallet could determine your level of suffering and quality of life during treatment, according to a new study by Dana Farber Cancer Institute researchers. The findings appear today in the Journal of Clinical Oncology.

In a study in the February 2016 Issue (241:3) of Experimental Biology and Medicine researchers at The Pennsylvania State University College of Medicine, led by Dr. Pat McLaughlin, discovered that a novel biological pathway, the OGF-OGFr axis, regulates cell proliferation in normal and abnormal cells and tissues. The non-classical opioid receptor, OGFr, was first discovered in the 1980s in neural cancer cells and normal rodent brain through collaborative work with Drs. Ian S. Zagon and Steven R. Goodman, and subsequently was isolated, characterized, and cloned.

The post-translational addition of ubiquitin to proteins by enzymes of the E3 ubiquitin ligase family is largely recognized as a means to target misfolded or unwanted proteins for degradation by the proteasome. However, it is now understood that ubiquitination serves as a signal to modify a number of cellular functions such as protein trafficking, cell signaling, DNA repair, chromatin modifications, cell-cycle progression, and cell death.

Minneapolis - Health care providers play an important role in providing accurate information to adolescents about sexual health issues, including prevention of pregnancy and sexually transmitted infections (STIs). There has been limited research, however, on how to best provide effective discussions about sexual health with Asian-American adolescents in a culturally sensitive manner.

PROVIDENCE, R.I. [Brown University] -- Brown University engineers have developed a new technique to help researchers understand how cells move through complex tissues in the body. They hope the tool will be useful in understanding all kinds of cell movements, from how cancer cells migrate to how immune cells make their way to infection sites.

The technique is described in a paper published in the Proceedings of the National Academy of Sciences.

Skimping on sleep has long been associated with overeating, poor food choices and weight gain. Now a new study shows how sleep loss initiates this process, amplifying and extending blood levels of a chemical signal that enhances the joy of eating, particularly the guilty pleasures gained from sweet or salty, high-fat snack foods.

The findings were published Feb. 29, 2016, in the journal SLEEP.

ITHACA, N.Y. - Researchers at Cornell University have discovered that bone does something better than most man-made materials: it bounces back after it breaks. In an article published in the Proceedings of the National Academy of Sciences this week Cornell scientists report that cancellous bone -- the spongy foam-like type of bone found near joints and in the vertebrae that is involved in most osteoporosis-related fractures -- displays unique material properties that allow it to recover shape after it breaks.