Pregnant women can be protected from malaria, a major cause of prematurity, low birth weight and death in infants in Africa, with dihydroartemisinin-piperaquine (DP), an artemisinin combination therapy that is already widely used to treat malaria in adults, according to a study by researchers at UC San Francisco and in Uganda.
The study, published March 10, 2016, in the New England Journal of Medicine, is among the first to show that artemisinin combination therapies like DP, which are effective against drug-resistant parasites, can be used to prevent malaria in pregnancy.