Some patients with breast cancer, lung cancer and leukaemia seem to fare poorly after treatment because of the effects of a particular gene, a new study finds.
The gene, called CYP3A7, is normally only active in infancy, but in some people it continues to be switched on into adulthood, and over-activates their metabolism.
Adults with active copies of the gene produce enzymes that break down hormones and about half of all clinically used drugs - potentially reducing the effectiveness of some cancer treatments.