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JERUSALEM and NEW YORK, NY (March 16, 2016) -- Scientists from The Hebrew University of Jerusalem, Columbia University Medical Center (CUMC) and The New York Stem Cell Foundation Research Institute (NYSCF) have succeeded in generating a new type of embryonic stem cell that carries a single copy of the human genome, instead of the two copies typically found in normal stem cells. The scientists reported their findings today in the journal Nature.

A controlled human challenge study shows that a candidate dengue vaccine can fully protect healthy volunteers who were intentionally infected with a weak form of the dengue virus. This type of study, among the first of its kind to be conducted for dengue, may offer a valuable tool for screening potential dengue vaccines before launching costly, and often risky, large-scale trials in dengue-endemic areas. The human challenge test could thus help speed up the development and guide the design of dengue vaccines, researchers say.

Scientists from The Hebrew University of Jerusalem, Columbia University Medical Center (CUMC) and The New York Stem Cell Foundation Research Institute (NYSCF) have succeeded in generating a new type of embryonic stem cell that carries a single copy of the human genome, instead of the two copies typically found in normal stem cells. The scientists reported their findings today in the journal Nature.

The stem cells described in this paper are the first human cells that are known to be capable of cell division with just one copy of the parent cell's genome.

• Between 3 and 6 million people in the UK suffer some degree of urinary incontinence
• The NHS carries out 13,500 operations each year to treat urinary incontinence, with 15% of women suffering serious complications as a result
• The researcher at Sheffield have developed a softer, elastic material to be used in surgery which replicates the natural recoil of the pelvic floor

As key players in the immune system, T cells provide tumor surveillance and have direct antitumor effects. However, tumors can escape T-cell attack through various mechanisms in the tumor microenvironment. Reactivating the antitumor effects of T cells has shown great clinical benefits in treating various cancers. The current T cell-based cancer immunotherapies are, nevertheless, only effective in a limited group of patients. New cancer immunotherapies are needed, therefore, to benefit more patients.

Researchers from the Genes, Development and Disease Group, headed by Erwin Wagner at the Spanish National Cancer Research Centre (CNIO) have discovered that psoriasis patients experience a widespread bone loss as a result of the disease. In addition, this paper, which is being published in the journal Science Translational Medicine, describes the molecular communication that is established between the inflamed skin and loss of bone mass.

Thank your mothers: A research collaboration between UC Santa Barbara and L'École Normale Supérieure in Paris has proven that deterministic maternal effects can give offspring a better start on life.

New research finds improvement in overall survival rates among men with aggressive prostate cancer who were treated with radiation at a facility that frequently performs that treatment.

In a new study led by researchers at Brigham and Women's Hospital, investigators looked at men with aggressive prostate cancer who were treated with radiation as well as the case volume of the facility at which they were treated. They found that receiving radiation at a facility that treats a high volume of prostate cancer patients with radiation was associated with improved overall survival.

COLUMBUS, Ohio - Human use of copper dating back to the Bronze Age has shaped the evolution of bacteria, leading to bugs that are highly resistant to the metal's antibacterial properties.

Large amounts of copper are toxic to people and to most living cells. But our immune systems use some copper to fend off bacteria that could make us sick.

WASHINGTON -- It's important to know how microorganisms -- particularly pathogenic microbes -- grow under various conditions. Certain bacteria can cause food poisoning when eaten and bacterial growth in medical blood supplies, while rare, might necessitate discarding the blood.

Now a group of researchers from Zhejiang Normal University in China and Umeå University in Sweden report a fast, accurate, and noninvasive technique for monitoring bacterial growth. They report the results in Applied Optics, a journal of The Optical Society (OSA).

DENVER - Trained technician screeners with assisted computer-aided nodule detection or computer vision (CV) screening workstations can efficiently and accurately review and triage abnormal low-dose computed topography (LDCT) scans for radiologist review.

We know that human-induced environmental changes are responsible for coral bleaching, disease, and infertility. Loss of the world's stony coral reefs - up to 30% in the next 30 years, according to some estimates - will mean loss of their services, including sequestering some 70-90 million tons of carbon each year and supporting enormous marine biodiversity. Yet despite many advances, we are still far from understanding the causes and processes contributing to the corals' demise.

When one eats may be as important as what one eats. New research at the Weizmann Institute of Science and in Germany, which recently appeared in the Proceedings of the National Academy of Sciences (PNAS), suggests that the cells' power plants - the mitochondria - are highly regulated by the body's biological, or circadian, clocks. This may help explain why people who sleep and eat out of phase with their circadian clocks are at higher risk of developing obesity, diabetes and metabolic syndrome.

People sometimes rely on the stereotype of a kid living in their parents' basement to illustrate poor socialization and isolation.

But the basement-dwellers may be connected with others in ways that those who are "out in the world" might not. And that seems to be the case for a group of cave crickets.

Recently published research by a team of scientists found that a sub-genus (a group of species) of crickets, Ceuthophilus, which is known to venture out of caves, show a higher degree of genetic isolation than its cousins, Geotettix, who live strictly inside the caves.

(WASHINGTON, March 16, 2016) - Despite significant advances in hemophilia therapies and increased access to integrated treatment centers over the last half century, men with severe forms of this disease still experience physical limitations and disability, according to new research published online today in Blood, the Journal of the American Society of Hematology (ASH).