A new breast cancer staging system developed by researchers at The University of TexasMD Anderson Cancer Center finds that incorporating tumor biology is a critical prognostic indicator for women who undergo neoadjuvant, or pre-surgical, therapy for breast cancer.
The Neo-Bioscore staging system, published in JAMA Oncology, incorporates HER2 status, thereby allowing for more precise prognostic stratification of all breast cancer subtypes. Understanding a patient's individual response to therapy could inform clinicians of which patients would benefit from additional therapy.