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Nanotechnology for label-free colorimetric detection of c-myc mRNA oncogene

Given the important role in functioning as oncogenes or tumor suppressors, c-myc mRNA has emerged as a potential biomarker for cancer detection. In particular, abnormal expression of mRNAs is commonly observed at early stages of colon cancer development. Therefore, sensitive detection of c-myc mRNA has become a promising approach to achieving early clinical diagnosis of cancer and paves the way for precision medicine. Recently, a China-U.S.

Blurred lines: Human sex chromosome swapping occurs more often than previously thought

It turns out that the rigid "line in the sand" over which the human sex chromosomes---the Y and X--- go to avoid crossing over is a bit blurrier than previously thought. Contrary to the current scientific consensus, Arizona State University assistant professor Melissa Wilson Sayres has led a research team that has shown that X and Y DNA swapping may occur much more often. And this promiscuous swapping, may in turn, aid in our understanding of human history and diversity, health and disease, as well as blur rigid chromosomal interpretations of sexual identity.

Decreased blood vessel leakage can improve cancer therapy and reduce tumor spread

Cancer therapy is often hampered by the accumulation of fluids in and around the tumour, which is caused by leakage from the blood vessels in the tumour. Researchers at Uppsala University now show how leakage from blood vessels is regulated. They have identified a novel mechanism whereby leakage can be suppressed to improve the result of chemotherapy and reduce the spread of tumours in mice. The results have been published in the scientific journal Nature Communications.

Study finds benefits of device for inserting IUDs after birth, Stanford researcher says

A simple tool designed for inserting an intrauterine device may offer women in the developing world a convenient, low-cost option for long-term contraception.

Practitioners can easily and effectively use the device in low-resource settings to place an IUD in women just after they've given birth, according to a pilot study led by a Stanford University School of Medicine researcher.

Warning: High-intensity training could hurt you if you're not an athlete

High-intensity 'sprint training' may be gaining popularity at gyms, but if you're new to this form of exercise, the workout could do more harm than good.

A study by Canadian and European researchers found signs of stress in the muscle tissues of their non-athlete, untrained subjects after ultra-intense leg and arm cycling exercises. Perhaps more concerning, researchers reported the untrained subjects had a weakened ability to fight off free radicals, molecules that can alter DNA and harm healthy cells.

Using frog foam to deliver antibiotics

Today, at the Microbiology Society's Annual Conference in Liverpool, scientists will show that the foam made by Trinidadian frogs represents a new, non-toxic antibiotic delivery system that may help to prevent infections.

While mating, Tungara frogs (Engystomops pustulosus) release a protein cocktail that they beat into a foam with their back legs. The frogs - less than 5 centimetres long - lay their eggs in these foam nests to protect them from disease, predators and environmental stresses.

Personality traits can be revealed by movement, study shows

A pioneering new study has revealed how an individual's movement can give a unique insight into their inherent personality traits.

The ground-breaking study could open up new pathways for health professionals to diagnose and treat mental health conditions in the future.

A team of experts, including from the University of Exeter, has shown that people who display similar behavioural characteristics tend to move their bodies in the same way.

Adherence to Japanese diet guidelines linked to longer life

Closer adherence to Japanese dietary guidelines is associated with a lower risk of death from all causes and death from cardiovascular disease, particularly stroke, finds a study published by The BMJ today.

The findings suggest that balanced consumption of grains, vegetables, fruits and adequate intake of fish and meat, can contribute to longevity in the Japanese population.

In 2005, the Japanese government developed the spinning top - a Japanese food guide - to illustrate the balance and quantity of food in the daily Japanese diet.

Experts urge UK parliament to take action to reduce food waste

As UK supermarkets pledge to cut food waste by 20% within the next decade, experts are calling on the government to take legislative action and debate the Food Waste (Reduction) Bill.

Writing in The BMJ today, Professors Andy Haines and Tim Lang, and Dr Jennie Macdiarmid, say the government's failure to respond positively to the proposed bill "should not detract from the need to pursue legislation to reduce food waste as part of an integrated approach to improving health, increasing food security, and reducing environmental damage."

The Lancet Oncology: Study suggests most female childhood cancer survivors have good chance of becoming pregnant

For women who have survived childhood cancer, the impact of modern chemotherapy regimens on the likelihood of becoming pregnant is generally small, and most have a good chance of conceiving, according to one of the largest studies of its kind published in The Lancet Oncology. In contrast, male survivors of childhood cancer are significantly less likely to have children, especially if they are treated with chemotherapy regimens containing high doses of commonly used alkylating drugs [1] and cisplatin.

MEGA evolutionary software re-engineered to handle today's big data demands

A Temple University-led research team has released a new version of their popular MEGA (Molecular Evolutionary Genomics Analysis) software, one of the most highly downloaded and widely used tools used by scientists worldwide to harness large-scale DNA sets for comparative studies.

At its core, MEGA is a powerful bioinformatics tool designed to help researchers identify key patterns among the diversity and complexity of life on Earth, and unravel the mysteries of human evolution, health and disease coded within the genome.

Gene variants found to strongly improve bone density in girls

Pediatric researchers have found that rare genetic changes strongly increase the likelihood that a child will have higher bone density, but only in girls. Because childhood and adolescence are critical periods for bone formation, these gene variants play an important role in increasing bone strength and reducing vulnerability to fractures later in a woman's life.

Government use of technology has potential to increase food security

AMES, Iowa - Acceptance of information technology can play a vital role in meeting the demand for food in developing countries, according to a new study by Iowa State University researchers. The research is published in the journal Information Technologies and International Development.

New guideline addresses long-term needs of head and neck cancer survivors

ATLANTA - March 22, 2016-A new American Cancer Society guideline provides clinicians with recommendations on key areas of clinical follow-up care for survivors of head and neck cancer, a growing population numbering approximately 436,060 and accounting for 3% of all cancer survivors living in the United States.

Scientists distinguish molecules most capable of fighting prostate cancer

Scientists from MIPT (Moscow Institute of Physics and Technology), MSU (Moscow State University), and National University of Science and Technology "MISIS" provided an overview of the most promising compounds which can be used as medications for prostate cancer. The article was published in the Journal of Drug Targeting.