Body

Choir singing boosts immune system activity in cancer patients and carers, study shows

Singing in a choir for just one hour boosts levels of immune proteins in people affected by cancer, reduces stress and improves mood, which in turn could have a positive impact on overall health, a new study by Tenovus Cancer Care and the Royal College of Music published today in ecancermedicalscience has found.

The research raises the possibility that singing in choir rehearsals could help to put people in the best possible position to receive treatment, maintain remission and support cancer patients.

New immune-stimulating drug, with chemo, shrinks pancreas tumors

The results of an early-stage (phase 1b) clinical trial for pancreatic cancer show that an experimental therapy can control tumors well enough to make some patients eligible for surgery, according to data published in The Lancet Oncology by a Wilmot Cancer Institute investigator.

To treat a leading cause of osteoporosis, surgery is better than widely used medications

While most cases of osteoporosis are caused by normal aging, another leading cause of the bone-loss disease is a condition called hyperparathyroidism, in which the parathyroid glands release an excessive amount of a hormone that regulates the body's calcium levels.

Doctors commonly treat hyperparathyroidism using a class of prescription drugs called bisphosphonates, including alendronate (marketed under the brand name Fosamax) and ibandronate (Boniva), which are supposed to strengthen bones.

Device that detects congestion in the lung improves heart failure outcomes

CHICAGO (April 4, 2016) -- In patients with heart failure, use of an investigational device that monitors the accumulation of fluid in the lungs appeared to cut heart failure-related hospitalizations by more than half, meeting the study's primary endpoint, and reduced deaths from any cause by 39 percent per year compared with standard assessment and treatment, researchers reported at the American College of Cardiology's 65th Annual Scientific Session.

Shorter, intensive radiation can be recommended in early prostate cancer

DURHAM, N.C. -- Giving early-stage prostate cancer patients a slightly higher daily dose of radiation can cut more than two weeks from the current treatment regimen without compromising cancer control, according to a national study led by a Duke Cancer Institute researcher.

Precision medicine brings new hope to those with advanced urothelial cancer

Five of six patients with advanced metastatic urothelial cancer and at least one of two specific genetic abnormalities, responded to treatment with afatinib, which was approved in 2013 by the Food and Drug Administration for patients with lung cancer, researchers report online in the Journal of Clinical Oncology.

One patient, who had both mutations, had stable disease for 16 months after taking afatinib. None of the other 17 patients in the trial, who lacked those specific abnormalities, had a significant response to the drug.

A chink in the armor of breast cancer cells

Working with human breast cancer cells, a team of scientists from Ann & Robert H. Lurie Children's Hospital of Chicago have successfully turned off a misbehaving protein that fuels the growth of a particularly aggressive, drug-resistant form of the disease known as triple-negative breast cancer.

In a set of lab experiments, the team managed to neutralize the protein, called Nodal, a growth factor already known for its role in early embryonic development.

A description of the work is published in the March 23 issue of the journal Cell Cycle.

Cancer research at Marshall University shows promise for combating deadly lung cancer

A study by researchers at Marshall University Joan C. Edwards School of Medicine has found that blocking the blood supply of small cell lung cancer tumors may help reduce their growth and delay the regrowth process after treatment. Small cell lung cancer is considered the most lethal of all lung cancers.

Researchers use single molecule of DNA to create world's smallest diode

Athens, Ga. - Researchers at the University of Georgia and at Ben-Gurion University in Israel have demonstrated for the first time that nanoscale electronic components can be made from single DNA molecules. Their study, published in the journal Nature Chemistry, represents a promising advance in the search for a replacement for the silicon chip.

The finding may eventually lead to smaller, more powerful and more advanced electronic devices, according to the study's lead author, Bingqian Xu.

Researchers have developed successful new treatment against the deadly Junin virus

GALVESTON, Texas - A team of researchers have made a discovery that could lead to the development of treatment for a deadly virus spread by rodents.

TSRI scientists: Immune cell transforms from 'Clark Kent' to 'Superman'

LA, JOLLA, CA - April 4, 2016 - A new study led by scientists at The Scripps Research Institute (TSRI) reveals a previously unknown type of immune cell. The discovery opens new avenues in the effort to develop novel therapies for autoimmune diseases such as type 1 diabetes.

The newly discovered cells resemble conventional T cells, yet are biased toward becoming T regulatory cells (Tregs), which protect the body from autoimmune disease.

Study suggests commercial bumble bee industry amplified a fungal pathogen of bees

CHAMPAIGN, Ill. -- Scientists hoping to explain widespread declines in wild bumble bee populations have conducted the first long-term genetic study of Nosema bombi, a key fungal pathogen of honey bees and bumble bees.

Final stampede results: Glycemic benefits of bariatric surgery persist over time

EMBARGOED UNTIL 2 p.m. CT Monday, April 4, 2016, CHICAGO: In the final, five-year follow-up report from the influential STAMPEDE trial, Cleveland Clinic research shows that bariatric surgery's beneficial effects on blood glucose control in mild and moderately obese patients with type 2 diabetes may persist for up to five years, with the advantage over diabetes medications-only approach widening over time.

The five-year follow-up also reported that:

Recent evolutionary change allows a fruit fly to dine on a toxic fruit

MADISON, Wis. -- A fruit called the noni -- now hyped for a vast array of unproven health benefits -- is distinctly unhealthy for the fruit fly, which has fascinated geneticists for a century. For the species of Drosophila that lives in labs around the world, noni signifies extermination with extreme prejudice: A fly will die if it eats yeast growing on noni.

Coral reefs highlight the key role of existing biodiversity for climate change adaptation

New research on coral reefs led by the University of Southampton suggests that existing biodiversity will be essential for the successful adaptation of ecosystems to climate change.