Working with human breast cancer cells, a team of scientists from Ann & Robert H. Lurie Children's Hospital of Chicago have successfully turned off a misbehaving protein that fuels the growth of a particularly aggressive, drug-resistant form of the disease known as triple-negative breast cancer.
In a set of lab experiments, the team managed to neutralize the protein, called Nodal, a growth factor already known for its role in early embryonic development.
A description of the work is published in the March 23 issue of the journal Cell Cycle.