Body

Sophia Antipolis - June 14, 2016: Fifteen minutes of daily exercise is associated with a 22% lower risk of death and may be a reasonable target for older adults, reveals research presented today at the EuroPRevent 2016 meeting by Dr David Hupin, a physician in the Department of Clinical and Exercise Physiology, University Hospital of Saint-Etienne in Saint-Etienne, France.1

In an analysis that included nearly 30,000 overweight or obese adults, compared with placebo, orlistat, lorcaserin, naltrexone-bupropion, phentermine-topiramate, and liraglutide were each associated with achieving at least 5 percent weight loss at 52 weeks, and phentermine-topiramate and liraglutide were associated with the highest odds of achieving at least 5 percent weight loss, according to a study appearing in the June 14 issue of JAMA.

Prescription of long-acting opioids for chronic noncancer pain was associated with an increased risk of all-cause mortality, including deaths from causes other than overdose, compared with anticonvulsants or cyclic antidepressants, according to a study appearing in the June 14, 2016 issue of JAMA.

(Boston) -- To date, there are no methods that can quickly and accurately detect pathogens in blood to allow the diagnosis of systemic bloodstream infections that can lead to life-threatening sepsis. The standard of care for detecting such blood-borne infections is blood culture, but this takes days to complete, only identifies pathogens in less than 30% of patients with fulminant infections, and it is not able to detect toxic fragments of dead pathogens that also drive the exaggerated inflammatory reactions leading to sepsis.

Using genome sequencing, researchers from the University of British Columbia, along with colleagues at the Imperial College in London, now have the ability to determine when a tuberculosis (TB) outbreak is over.

A virus that infects major freshwater bacteria appears to use stolen bits of immune system DNA to highjack their hosts' immune response.

Microbiologists have discovered that the virus, Cyanophage N1, carries a DNA sequence--a CRISPR--that is generally used by bacteria to fight off viral infection.

The new and sixth volume of Research on Chrysomelidae consists of five research articles devoted to the latest findings about the amazing family of over 37,000 leaf beetle species from more than 2,500 genera.

Hitting a plateau in strength training? The answer to overcoming it might lie in accentuated eccentric loading (AEL).

Amsterdam, June 14, 2016 - Tiny bubbles filled with the sleep hormone melatonin can make breast cancer treatment more effective, which means people need a lower dose, giving them less severe side effects. In a new study published in Colloids and Surfaces B: Biointerfaces, researchers show that the bubbles, called nanostructured lipid carriers (NLCs), made tamoxifen stronger and help it kill cancer cells.

A few weeks ago, the biologist Juliano Sarmento Cabral (33) celebrated a handsome success. Together with former colleagues from the University of Göttingen, he published an article in the journal Nature. One finding: In order to understand the diversity of species on islands such as Hawaii, Galapagos or the Canary Islands, you have to look far back into the past - at least as far as the last ice age 21,000 years ago.

One of the most fundamental goals in ecology - determining the community assembly processes that have structured local communities - has been increasingly studied through the analysis of functional and phylogenetic diversity.

Neuherberg, June 14, 2016. Scientists at the Helmholtz Zentrum München and the Ludwig Maximilians University of Munich (LMU) have developed a new method of predicting disease progression in gliobastoma patients who have undergone standard treatment. Their findings, published in the journal Oncotarget, show that four miRNAs may hold the vital clue. An application for the corresponding patent has already been filed.

The first days after HIV infection are very important because sexual partners are exposed to extremely high risks of infection due to the subsequent high viral load in the infected person. Additionally, this period of time determines the further course of HIV infection.

"The affected countries will have a major problem if we do not manage to control salmonella bloodstream infections with new antibiotics such as ciprofloxacin," cautions Prof Jürgen May. He has conducted numerous studies on salmonella infections in sub-Saharan Africa, particularly in Kumasi in Ghana, where the Bernhard Nocht Institute and the DZIF are in close partnership with researchers from the Kumasi Centre for Collaborative Research in Tropical Medicine.

PROVIDENCE, R.I. [Brown University] -- As Brazilians make final preparations to host the world's premier showcase of athleticism, the Olympics, a new paper in the Journal of the American Heart Association reports that many citizens of the host country are not taking enough advantage of the health benefits of exercise.