Cells that become senescent irrevocably stop dividing under stress, spewing out a mix of inflammatory proteins that lead to chronic inflammation as more and more of the cells accumulate over time. Publishing in the September 24 edition of Cell Reports, researchers at the Buck Institute identified 44 specific senescence-associated proteins that are involved in blood clotting, marking the first time that cellular senescence has been associated with age-related blood clots.
BOSTON (Sept. 24, 2019, 11:00 a.m. ET)--Despite years of steady advice and guidance on healthy eating, a 'report card' on the American diet shows adults are still consuming too many low-quality carbohydrates and more saturated fat than recommended, according to researchers at the Friedman School of Nutrition Science and Policy at Tufts University and the Harvard T.H. Chan School of Public Health.
Almost everyone fidgets, said Cold Spring Harbor Laboratory Associate Professor Anne Churchland. She referred to a collage of videos she compiled of different people rocking back and forth in their chairs, clicking a pen, shaking their legs.
"This is a collection of uninstructed movements," she explained. "These are all people who were thinking and talking, and these are probably familiar fidgets that you've seen people do."
WASHINGTON, D.C., September 24, 2019 -- Being able to accurately forecast how much solar energy reaches the surface of the Earth is key to guiding decisions for running solar power plants.
While day-ahead forecasts have become more accurate in recent years, the solar community lacks a unified verification procedure, and assessing how one forecast compares to another is difficult. New work in the Journal of Renewable and Sustainable Energy, from AIP Publishing, looks to provide a standard of reference to the field.
WASHINGTON, D.C., September 24, 2019 -- By studying the brain dynamics of 28 subjects with epilepsy, scientists demonstrated there is no evidence for a previously suspected warning sign for seizures known as "critical slowing down."
In 2013, some of the first seizure-prediction devices were developed and successfully tested. Although extensive research efforts have successfully identified predictors of imminent seizures, the concept of critical slowing down as an index for seizure susceptibility has been controversial and remained unproven.
The novel small molecules, based on new target, new chemical structure and new antimicrobial mechanism, are different from those of existing antibiotics. The new drug candidates demonstrate much effective abilities of inhibiting bacterial growth than commonly used antibiotics, yet with no toxicity to human cells.
"The strategy was to design the drug to be able to hook into the hole of the FTase and GGTase I, otherwise the surface of the proteins are too large and slippery," Dr. Junko Ohkanda of Shinshu University explains her strategy behind her paper chosen by Chemistry - A European Journal as a "Hot Paper".
Today's electronics industry is increasingly focusing on computers or smartphones with screens that can be folded or rolled. Smart clothing items make use of wearable micro-devices or sensors to monitor bodily functions, for example. However, all these devices need an energy source, which is usually a lithium-ion battery. Unfortunately, commercial batteries are typically heavy and rigid, making it fundamentally unsuitable for applications in flexible electronics or textiles.
QUT researchers have come up with a new, safe way to clean up oil spills using compounds equally useful as common household cleaning products.
There have been more than 700 oil spills worldwide in the past 20 years, polluting oceans and coastlines as well as endangering marine ecology and other wildlife.
Associate Professor Jingsan Xu said the team from QUT's Science and Engineering Faculty, had invented a nontoxic, low-cost, easily processed foam for oil removal.
A research group comprising Associate Professor Taku Hasobe and Assistant Professor Hayato Sakai of the Keio University Faculty of Science and Technology, Toshiyuki Saegusa of the Keio University Graduate School of Science and Technology (completed master's program in 2019), and Professor Yasuhiro Kobori and postdoctoral researcher Hiroki Nagashima of the Kobe University Molecular Photoscience Research Center found that when light was exposed to the surface of a tetracene alkanethiol-modified gold nanocluster, which they developed themselves, twice as many excitons could be converted compar