LA JOLLA--(September 24, 2019) Colorectal cancer is a common lethal disease, and treatment decisions are increasingly influenced by which genes are mutated within each patient. Some patients with a certain gene mutation benefit from a chemotherapy drug called cetuximab, although the mechanism of how this drug worked was unknown.

Phoenix, Arizona, USA: Figuring out what lies ahead for our species and our planet is one of the most pressing and challenging tasks for climate scientists. While models are very useful, there is nothing quite like Earth's history to reveal details about how oceans, animals, and plants respond to and recover from a warming world.

The two most recent major global warming events are especially instructive -- and worrisome, say scientists presenting new research Wednesday at the Annual Meeting of the Geological Society of America.

Ancient analogs

Tropical Storm Jerry continued to weaken as warnings were in effect for Bermuda on Sept. 24.  Jerry appeared less organized on visible imagery from NASA-NOAA's Suomi NPP satellite because wind shear was taking its toll on the storm.

AMHERST, Mass. - This week, representatives of 195 member governments of the Intergovernmental Panel on Climate Change (IPCC) are meeting at the Oceanographic Museum of Monaco with dozens of climate scientists who have prepared a draft "Summary for Policymakers" of their "Special Report on the Ocean and Cryosphere in a Changing Climate (SROCC)."

Tropical Storm Lorenzo continued to strengthen and appeared more organized on visible imagery from NASA-NOAA's Suomi NPP satellite.

The shape of the storm is a clue to forecasters that a storm is either strengthening or weakening. If a storm takes on a more rounded shape it is getting more organized and strengthening. Conversely, if it becomes less rounded or elongated, it is a sign the storm is weakening.

There are no scales for weighing black holes. Yet astrophysicists from the Moscow Institute of Physics and Technology have devised a new way for indirectly measuring the mass of a black hole, while also confirming its existence. They tested the new method, reported in the Monthly Notices of the Royal Astronomical Society, on the Messier 87 active galaxy.

DURHAM, N.C. -- Numerous studies show that children who had a rough start in life are more likely to have health problems later on.

The enduring effects of early adversity aren't unique to humans. But for baboons, the impacts aren't just borne by one generation -- the next generation bears the brunt as well, said Susan Alberts, chair of evolutionary anthropology at Duke University.

The findings come from a study of 169 baboon mothers and nearly 700 of their offspring that were monitored almost daily between 1976 and 2017 in Amboseli National Park in Kenya.

The cells of our immune system constantly communicate with one another by exchanging complex protein molecules. A team led by researchers from the Technical University of Munich (TUM) has now revealed how dedicated cellular control proteins, referred to as chaperones, detect immature immune signaling proteins and prevent them from leaving the cell.

"Keep your eyes on the road."

With the recent advances in vehicle-assisted safety technology and in-car displays, this old adage has a new meaning, thanks to two new applications of eye-tracking technology developed by researchers at the University of Missouri.

Designing a better collision avoidance warning

Observing how someone's eyes change -- specifically the pupil -- while they respond to an alert given by a vehicle collision avoidance warning could one day help scientists design safer systems.

An international research team including scientists from the University of Cologne, Germany, numerous Iranian universities and the University of Sydney, Australia, has shown that today's Iranian population is composed of partially highly heterogeneous ethnic groups, exhibiting a high degree of genetic variation. In many cases, their source goes back many thousands of years.