Earth
Enough water will come from the ground as a byproduct of oil production from unconventional reservoirs during the coming decades to theoretically counter the need to use fresh water for hydraulic fracturing operations in many of the nation's large oil-producing areas. But while other industries, such as agriculture, might want to recycle some of that water for their own needs, water quality issues and the potential costs involved mean it could be best to keep the water in the oil patch.
Utrecht, The Netherlands, 20th of February 2020. While the genome editing tool CRISPR/Cas9, developed in 2012, cuts a mutation out of a gene and replaces it with a gene-piece, a newer type of CRISPR, called base-editing, can repair a mutation without cutting the DNA. Therefore, genome editing using base-editor is considered safer. Scientists from the research groups of Hans Clevers (Hubrecht Institute) and Jeffrey Beekman (UMC Utrecht) show for the first time that this base-editing can safely cure cystic fibrosis in stem cells derived from patients.
BOSTON - Deep within the lining of the human intestine lies the source of the organ's ability to renew itself and recover from damage: intestinal stem cells (ISCs), lodged in pockets of tissue called crypts, generate the cells that continuously repopulate the intestinal lining. Even the stem cells themselves have a safety net: when they're damaged, healthy replacements appear in less than a week.
What The Study Did: Data from 82 prison inmates treated in a glaucoma clinic at an academic hospital were used in this observational study to report on how treatment and follow-up, including medication adherence, were are managed.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
Authors: Levi N. Kanu, M.D., of the University of Illinois at Chicago, is the corresponding author.
(doi:10.1001/jamaophthalmol.2020.0001)
Image-based sexual abuse in Australia is increasing, according to new research.
A survey of more than 2000 Australians found 1 in 3 had been victims of image-based abuse, compared with 1 in 5 in 2016.
The survey also found the perpetration of image-based abuse had increased, with 1 in 6 people surveyed reporting they had taken, shared or made threats to share a nude or sexual image of a person without that person's consent, compared with 1 in 10 of those surveyed in 2016.
New scientific findings released today in the peer-reviewed journal Nature Communications, show that expansion Aof the Pacific Remote Islands and Papahanaumokuakea marine national monuments did not cause overall economic harm to the Hawaii-based longline tuna fishing fleet.
A recent study of indigenous people in southern Chile challenges some Western assumptions about children's emotional capabilities and highlights the potential value of spending time outdoors to help children regulate their emotions.
"I think many people, particularly in Western cultures, think children are less capable than they actually are," says Amy Halberstadt, a professor of psychology at North Carolina State University and corresponding author of a paper on the work. "Our study shows that this is not universal.
Two research teams from the Max Delbrück Center for Molecular Medicine and their collaborators have produced a detailed cell atlas of an entire salivary gland tumor in a mouse model, mapping individual cells throughout the tumor and its surrounding tissue. The "single cell" approach, recently described in Nature Communications, has provided key insights about cellular composition changes through the earliest stages of cancer development.
ITHACA, N.Y. - Bernie Sanders and Joe Biden lead Democratic presidential nominees among registered Latino voters heading into the Feb. 22 Nevada caucuses, the first contest in a diverse state. Nationally, registered Latino voters favor any of the Democratic contenders over President Donald Trump by large margins, and rate health care and racism as significant concerns.
The loss of the identity of insulin-secreting beta cells in the islet of Langerhans, a process also called beta cell dedifferentiation, has been proposed to be a main reason for the development of diabetes. If and how dedifferentiated beta cells can be targeted by pharmacological intervention for beta cell regeneration is unknown.
In a first for quantum physics, University of Otago researchers have "held" individual atoms in place and observed previously unseen complex atomic interactions.
A myriad of equipment including lasers, mirrors, a vacuum chamber, and microscopes assembled in Otago's Department of Physics, plus a lot of time, energy, and expertise, have provided the ingredients to investigate this quantum process, which until now was only understood through statistical averaging from experiments involving large numbers of atoms.
Otago scientists studying sperm whales off the coast of Kaik?ura have discovered earthquakes affect their ability to find food for at least a year.
The University of Otago-led research is the first to examine the impact of a large earthquake on a population of marine mammals, and offers new insight into how top predators such as sperm whales react and adapt to a large-scale natural disturbance.
Changes in habitat use by a deep-diving predator in response to a coastal earthquake, has recently been published in Deep Sea Research Part I.
New research from the UBC's Okanagan campus, Harvard Medical School and Michigan State University suggests that levitating human plasma may lead to faster, more reliable, portable and simpler disease detection.
The researchers used a stream of electricity that acted like a magnet and separated protein from blood plasma. Plasma is the clear, liquid portion of blood that remains after red blood cells, white blood cells, platelets and other cellular components are removed.
A growing body of research shows that birds' spring migration has been getting earlier and earlier in recent decades. New research from The Auk: Ornithological Advances on Black-throated Blue Warblers, a common songbird that migrates from Canada and the eastern U.S. to Central America and back every year, uses fifty years of bird-banding data to add another piece to the puzzle, showing that little-studied fall migration patterns have been shifting over time as well.
Bottom Line: The loss of one copy of the miR15a/miR16-1 gene cluster promoted initiation and progression of multiple myeloma in mice.
Journal in Which the Study was Published: Published online in Blood Cancer Discovery, the latest journal of the American Association for Cancer Research
Author: Marta Chesi, PhD, associate professor of medicine at the Mayo Clinic