Culture

Few technologies have made as big a splash in recent years as CRISPR/Cas9, and rightfully so. CRISPR/Cas9, or clustered regularly interspaced palindromic repeats (CRISPR) and associated genes, is a bacterial gene editing toolbox that allows researchers to edit genomic sequences much more precisely and efficiently than previously possible, opening up doors to new ways of doing research. As with many new biotechnologies, the application of CRISPR in biology began with genetic model organisms such as Arabidopsis thaliana.

In a pilot study in adults with autism and depression, transcranial magnetic stimulation, or TMS, was effective in reducing depressive symptoms and had some effects on autistic symptoms, report researchers at the Medical University of South Carolina in Autism Research. This study suggests that TMS warrants further study as a potential treatment for adults with both depression and autism.

BOSTON - Results of a study show that enrollment in a program that supports housing and health needs of medically complex families was associated with improved child health and parent mental health within six months. The program, Housing Prescription as Health Care (HPHC), helps families experiencing homelessness and housing instability in Boston and uses a multi-dimensional approach to address families' specific needs.

Recent discoveries by two research teams in the Ira A. Fulton Schools of Engineering at Arizona State University are advancing the field of synthetic biology.

Assistant Professor Xiaojun Tian and Associate Professor Xiao Wang conducted a year-long collaboration with their laboratory groups in the School of Biological and Health Systems Engineering, one of the six Fulton Schools. Results from their novel research into ways that engineered gene circuits interact with biological host cells have been published this week in the scientific journal Nature Chemical Biology.

Researchers at the University of Iowa and the University of Georgia have developed a vaccine that fully protects mice against a lethal dose of MERS, a close cousin of the SARS-CoV2 coronavirus that causes COVID-19.

The vaccine uses a harmless virus to deliver a MERS coronavirus protein into cells to generate an immune response, and may hold promise for developing vaccines against other coronaviruses diseases, including COVID-19.

Washington, DC - April 7, 2020 - No vaccines exist that protect people against infections by coronaviruses, including SARS-CoV-2, which causes COVID-19, or the ones that cause SARS and MERS. As COVID-19 continues to wreak havoc, many labs around the world have developed a laser-like focus on understanding the virus and finding the best strategy for stopping it.

New understandings of how lipids function within tears could lead to better drugs for treating dry eye disease.

A new approach has given Hokkaido University researchers insight into the synthesis and functions of lipids found in tears. Their findings, published in the journal eLife, could help the search for new treatments for dry eye disease.

Scientists at Sanford Burnham Prebys have found a new way to kill pancreatic cancer cells by disrupting their pH equilibrium. The study, published in Cancer Discovery, reports how depleting an ion transport protein lowers the pH to a point that compromises pancreatic cancer cell growth.

A new method of evaluating and prioritising treatment for patients with suspected acute stroke, which has been used by the Stockholm health authority since 2017, has led to faster health interventions and better patient care, shows a new study from Karolinska Institutet published in the journal JAMA Neurology.

Joint research between Kobe University and Ushio Inc. has provided proof for the first time in the world that direct and repetitive illumination from 222nm ultraviolet radiation C (UVC), which is a powerful sterilizer, does not cause skin cancer. This suggests that 222nm UVC is also safe for human eyes and skin. This technology is expected to have a wide range of antibacterial and antiviral applications in medical facilities and daily life.

Ride-hailing trips increase the number of crashes for motorists and pedestrians at pick-up and drop-off locations, reports a new study from researchers at the Columbia University Mailman School of Public Health. The research is the first to use data for individual ride-hailing trips, rather than comparing cities where ride-hailing is available to those where it is not available. The findings are published in the journal Injury Prevention.

Below please find a summary of new coronavirus-related content published today in Annals of Internal Medicine. The summary is not intended to substitute for the full article as a source of information. A collection of coronavirus-related content is free to the public at http://go.annals.org/coronavirus.

1. Neither surgical nor cotton masks effectively filter SARS COV-2

A recent discovery by University of Arkansas physicists could help researchers establish the existence of quantum spin liquids, a new state of matter. They've been a mystery since they were first proposed in the 1970s. If proven to exist, quantum spin liquids would be a step toward much faster, next-generation quantum computing.

PHILADELPHIA - Multiple sclerosis (MS), characterized by increasing muscle weakness and paralysis, has a number of treatments that help stall progression of the disease when used early on in the disease. But the current treatments can hardly reverse damage that has already occurred in brain cells called neurons. New research suggests that a compound found in the peels of fruits such as apples and prunes, and some herbs, can reduce further damage to neurons, and also help rebuild the protective sheaths covering neurons, reversing the damage.

Washington, D.C., April 7, 2020 -- In states that have banned affirmative action, the share of underrepresented minorities among students admitted to and enrolling in public universities has steadily lost ground relative to changing demographic trends among those states' high school graduates, according to new research.

The study, by Mark Long at the University of Washington and Nicole Bateman at the Brookings Institution, was published today in Educational Evaluation and Policy Analysis, a peer-reviewed journal of the American Educational Research Association.