Culture
Transfer RNAs (tRNAs) deliver specific amino acids to ribosomes during translation of messenger RNA into proteins. The abundance of tRNAs can therefore have a profound impact on cell physiology, but measuring the amount of each tRNA in cells has been limited by technical challenges. Researchers at the Max Planck Institute of Biochemistry have now overcome these limitations with mim-tRNAseq, a method that can be used to quantify tRNAs in any organism and will help improve our understanding of tRNA regulation in health and disease.
BOSTON - Two novel calculators for predicting which patients admitted to the hospital with COVID-19 are at greatest risk of requiring mechanical ventilation or of in-hospital death have been developed and validated by Massachusetts General Hospital (MGH).
In recent years, engineers have found ways to modify the properties of some "two- dimensional" materials, which are just one or a few atoms thick, by stacking two layers together and rotating one slightly in relation to the other. This creates what are known as moiré patterns, where tiny shifts in the alignment of atoms between the two sheets create larger-scale patterns. It also changes the way electrons move through the material, in potentially useful ways.
Dropping out of high school, having schizophrenia, or being diagnosed with a co-occurring personality disorder increases the likelihood of someone becoming a "high utilizer" of inpatient psychiatric hospital services, according to a new study by researchers at The University of Texas Health Science Center at Houston (UTHealth). A high utilizer is someone who has been admitted three or more times within one year.
The research was published today in The Journal of Health Care for the Poor and Underserved.
MISSOULA - University of Montana researchers and their partners have discovered a slimy strategy used by bacteria to defeat antibiotics and other drugs used to combat infections afflicting people with cystic fibrosis. The research was published Feb. 23 in the journal Cell Reports.
COLUMBUS, Ohio - Politicization of the COVID-19 pandemic had a powerful influence over adherence to social distancing guidelines in the United States and why people did, or did not, comply during the lockdown days, a new study has found.
The analysis boiled down to whom study participants trusted most: scientists or President Donald Trump.
UCLA materials scientists and their colleagues have developed a new method to make synthetic biomaterials that mimic the internal structure, stretchiness, strength and durability of tendons and other biological tissues.
What The Study Did: This randomized clinical trial compares the effects of once-weekly subcutaneous semaglutide versussplacebo for weight management as an adjunct to intensive behavioral therapy with initial low-calorie diet in adults with overweight or obesity.
Authors: Thomas A. Wadden, Ph.D., of the University of Pennsylvania in Philadelphia, is the corresponding author.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
Many genetic variants have been found to have a linkage with genetic diseases, but the understanding of their functional roles in causing diseases are still limited. An international research team, including a biomedical scientist from City University of Hong Kong (CityU), has developed a high-throughput biological assay technique which enabled them to conduct a systematic analysis on the impact of nearly 100,000 genetic variants on the binding of transcription factors to DNA.
RESEARCHERS MAY HAVE UNCLOUDED THE MYSTERY OF COVID-19 'BRAIN FOG'
Media Contact: Michael E. Newman, mnewma25@jhmi.edu
PHILADELPHIA -- A second study of the injectable anti-obesity medication, semaglutide, has confirmed the large weight losses reported in a study earlier this month, establishing the reliability and robustness of this new drug. With obesity affecting more than 40 percent of American adults, the findings could have a major impact on weight management in primary care and other settings.
SAN ANTONIO -- Feb. 24, 2021 -- A Southwest Research Institute® (SwRI®) scientist examined 11 Mars years of image data to understand the seasonal processes that create linear gullies on the slopes of the megadune in the Russell crater on Mars. In early spring images, captured by two different cameras on the Mars Reconnaissance Orbiter, SwRI's Dr. Cynthia Dinwiddie noticed airborne plumes of dusty material associated with the linear dune gullies on the sand dune's downwind slope.
Immunologists at St. Jude Children's Research Hospital have discovered that tumors use a unique mechanism to switch on regulatory T cells to protect themselves from attack by the immune system. Surprisingly, the mechanism does not affect regulatory T cell function outside the tumor and may therefore limit the immune-associated toxicities of targeting regulatory T cells.
BROOKLYN, New York, Wednesday, February 24, 2021 -The Governance Lab (The GovLab) at the NYU Tandon School of Engineering released a report, "The Power of Virtual Communities," which examines the role online groups play in creating opportunities for people to build new kinds of meaningful communities they often could not form in real space.
Aged cheeses pack a punch of nutty, sharp flavor. Before they're fully mature, aged cheeses are either waxed or placed in brine for weeks to create a natural rind. However, the high salt content in brined cheeses deters some consumers. Now, researchers reporting in ACS Food Science & Technology present a shortened brining time for Parmigiano Reggiano that results in a less salty product, while still potentially maintaining the cheese's distinctive texture and flavor compounds.