Subcutaneous semaglutide vs. placebo as adjunct to intensive behavioral therapy on body weight in adults with overweight or obesity

What The Study Did: This randomized clinical trial compares the effects of once-weekly subcutaneous semaglutide versussplacebo for weight management as an adjunct to intensive behavioral therapy with initial low-calorie diet in adults with overweight or obesity.

Authors: Thomas A. Wadden, Ph.D., of the University of Pennsylvania in Philadelphia, is the corresponding author.

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(doi:10.1001/jama.2021.1831)

Editor's Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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