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PHILADELPHIA - A new type of cancer vaccine has yielded promising results in an initial clinical trial conducted at the Perelman School of Medicine at the University of Pennsylvania and the Abramson Cancer Center of the University of Pennsylvania. The personalized vaccine is made from patients' own immune cells, which are exposed in the laboratory to the contents of the patients' tumor cells, and then injected into the patients to initiate a wider immune response.
(Millbrook, NY) Road salt applied during the winter lingers in the environment, where it can pollute drinking water supplies. In a recent study in the Journal of Environmental Quality, researchers identify landscape and geological characteristics linked to elevated well water salinity in a suburban township in Southeastern New York.
People with a rare dementia that initially attacks the language center of the brain recruit other areas of the brain to decipher sentences, according to new research led by a University of Arizona cognitive scientist.
The study is one of the first to show that people with a neurodegenerative disease can call upon intact areas of the brain for help. People who have had strokes or traumatic brain injuries sometimes use additional regions of the brain to accomplish tasks that were handled by the now-injured part of the brain.
Our emotional state in a given moment may influence what we see, according to findings published in Psychological Science, a journal of the Association for Psychological Science. In two experiments, researchers found that participants saw a neutral face as smiling more when it was paired with an unseen positive image.
BLOOMINGTON, Ind. -- At a time when more Americans are living longer, the companies where many people spend their working lives have increasingly shorter lifespans, according to research from Indiana University's Kelley School of Business.
A paper by two Kelley professors, forthcoming in the Academy of Management Annals, found that the odds of a company surviving more than five years has declined dramatically since the 1960s and that this trend also holds for firms lasting 10, 15 and 20 years.
Eye drops developed by UBC researchers could one day treat glaucoma while you sleep - helping to heal a condition that is one of the leading causes of blindness around the world.
"Medicated eye drops are commonly used to treat glaucoma but they're often poorly absorbed. Less than five per cent of the drug stays in the eye because most of the drops just roll off the eye," said lead researcher Vikramaditya Yadav, a professor of chemical and biological engineering, and biomedical engineering at UBC.
(New York, NY- April 11, 2018) --Researchers from Mount Sinai and Sema4, a health information company and Mount Sinai venture, have discovered that giving metastatic bladder cancer patients simultaneous chemotherapy and immunotherapy is safe and that patients whose tumors have certain genetic mutations may respond particularly well to this combination approach, according to the results of a clinical trial published in European Urology.
NEW YORK, April 11, 2018 - Salaries for U.S. physicians edged higher this past year, with compensation increasing modestly for most specialties, while jumping 16% for psychiatrists. Still, the gender gaps in compensation remain unchanged and failed to budge for African-American physicians, according to the results of the 2018 Medscape Physician Compensation Report. Yet, despite concerns regarding pay equity and skyrocketing bureaucratic demands, the majority of physicians remain committed to the profession and are happy they chose to be doctors.
Vertebrate species, including humans, exposed to stress prenatally tend to have higher stress hormones after birth, according to a new Dartmouth-led study published in Scientific Reports.
Engineers at the University of California San Diego have developed a miniature, ultra-low power injectable biosensor that could be used for continuous, long-term alcohol monitoring. The chip is small enough to be implanted in the body just beneath the surface of the skin and is powered wirelessly by a wearable device, such as a smartwatch or patch.
SAN FRANCISCO, CA--April 10, 2018--Over a decade ago, Shinya Yamanaka and Kazutoshi Takahashi made a discovery that would revolutionize biomedical research and trigger the field of regenerative medicine. They learned how to reprogram human adult cells into cells that behave like embryonic stem cells. Scientists were shocked that something so complex could be done so simply, and they had thousands of questions.
Many mammals consume blood as part of their diet, but blood is actually a pretty poor source of energy. Only bats (order Chiroptera) include species that feed exclusively on blood.
So how do vampire bats manage to survive on such low-grade nourishment? A recently published article in Nature Ecology & Evolution provides part of the answer. The bats had to evolve in tandem with their microorganisms.
Targeted treatments have revolutionized care for lung cancer patients whose tumors harbor ALK or ROS1 alterations. Basically, cancers may use these genetic changes to drive their growth, but also become dependent on the action of these altered genes for their survival. Targeted treatments like crizotinib block the actions of ALK and ROS1, thus killing cancers that depend on them. However, when doctors target ALK or ROS1, cancers often evolve new ways to survive. After a period of success, targeted treatments against ALK+ and ROS1+ lung cancers often fail.
Researchers have identified specific predictive biomarkers that could help assess the level of risk for recurrence in patients with malignant glioma. The study, led by Henry Ford Health System's Department of Neurosurgery and Department of Public Health Sciences, was published today in Cell Reports.
Scientists have decoded faint distortions in the patterns of the universe's earliest light to map huge tubelike structures invisible to our eyes - known as filaments - that serve as superhighways for delivering matter to dense hubs such as galaxy clusters.