Culture
The researchers within the groups of Prof Dr Lars Schäfer and Prof Dr Enrica Bordignon, who work together in the Excellence Cluster Ruhr explores Solvation, Resolv in short, report in the Journal of the American Chemical Society of 16 March 2018.
"ABC transporters are fascinating biological nanomachines", says Lars Schäfer, head of the Molecular Simulation research group. These proteins couple the binding and chemical cleavage of ATP molecules, the chemical energy unit of the cell, with the transport of molecules through biological membranes.
13 April 2018, Paris, France: The fibroblast growth factor 19 (FGF19) engineered analogue, NGM282, inhibits bile acid synthesis, decreases markers of hepatic inflammation, and significantly improves markers of fibrosis in patients with primary sclerosing cholangitis (PSC), according to the results of a Phase 2, multicentre, randomized, double-blind, placebo-controlled study reported today. The study, which involved 62 patients with PSC diagnosed according to EASL criteria,7 offers hope of a new medical treatment for a condition in which effective drug therapies are currently limited.8
IF you want to know how to pour the perfect pint or create the ultimate cup of coffee, then you really need a mathematician.
That might not be the most obvious choice, but major companies are increasingly aware that they can solve conundrums and improve their products by calling on specialists in the burgeoning discipline known as industrial mathematics. They include William Lee, recently appointed professor in the subject at the University of Huddersfield.
SCIENTISTS at the University of Huddersfield have been using world-class new facilities to carry out experiments that could aid the development of nuclear fusion reactors, widely regarded as the "Holy Grail" solution to future energy needs.
By simulating the damage caused by high energy neutrons and alpha particles produced during the fusion process, the Huddersfield researchers have discovered that tungsten -- a favoured choice of metal within the reactor -- is liable to become brittle, leading to failure.
Individual pastures on livestock farms yield surprisingly dissimilar benefits to a farm's overall agricultural income, and those differences are most likely attributable to the varying levels of "soil health" provided by its grazing livestock, reveals a study published today.
The study, produced by an interdisciplinary team of 13 scientists and two PhD students from Rothamsted Research, evaluates how efficiently nutrients are used on a livestock farm, on a field-by-field basis for the first time, and links soil health to animal growth.
April 13, 2018--Even the briefest increase in airborne fine particulate matter PM2.5, pollution-causing particles that are about 3 percent of the diameter of human hair, is associated with the development of acute lower respiratory infection (ALRI) in young children, according to newly published research. Increases in PM2.5 levels also led to increased doctor visits for these lung infections.
People in crowded urban areas - especially poor areas - see fewer songbirds such as tits and finches, and more potential "nuisance" birds, such as pigeons, magpies and gulls, new research shows.
The University of Exeter and the British Trust for Ornithology examined ratios of birds-to-people and found areas of high-density housing have fewer birds overall - and the birds people do see are just as likely to cause a nuisance as to make them happy.
Engineers have proposed a coordinated control architecture for motion management in advanced driver assistance systems (ADAS) to increase safety and comfort across all vehicles, regardless of ADAS specifics.
They published their proposal in IEEE/CAA Journal of Automatica Sinica, a joint publication of the IEEE and the Chinese Association of Automation.
In 2013, the Nobel Prize in Physiology or Medicine was awarded to three scientists for their contributions to uncovering the mechanisms governing vesicle transport in cells. Their explanations provided both a conceptual and a mechanistic understanding of basic processes at the most fundamental level.
BUFFALO, N.Y. -- Each year, farmers in the U.S. purchase tens of millions of pounds of antibiotics that are approved for use in cows, pigs, fowl and other livestock.
When farmers repurpose the animals' manure as fertilizer or bedding, traces of the medicines leach into the environment, raising concerns that agriculture may be contributing to the rise of antibiotic-resistant bacteria.
New research holds troublesome insights with regard to the scope of this problem.
Researchers at the University of Washington have designed a convenient and natural product that uses proteins to rebuild tooth enamel and treat dental cavities.
The research finding was first published in ACS Biomaterials Science and Engineering.
"Remineralization guided by peptides is a healthy alternative to current dental health care," said lead author Mehmet Sarikaya, professor of materials science and engineering and adjunct professor in the Department of Chemical Engineering and Department of Oral Health Sciences.
Things are getting real for researchers in the UC Santa Barbara John Martinis/Google group. They are making good on their intentions to declare supremacy in a tight global race to build the first quantum machine to outperform the world's best classical supercomputers.
But what is quantum supremacy in a field where horizons are being widened on a regular basis, in which teams of the brightest quantum computing minds in the world routinely up the ante on the number and type of quantum bits ("qubits") they can build, each with their own range of qualities?
About a year and a half ago, a 6-year-old boy arrived at Children's Emergency Department after accidently removing his own gastrointestinal feeding tube. He wasn't a stranger to Children's National Health System: This young patient had spent plenty of time at the hospital since birth. Diagnosed in infancy with an intestinal pseudo-obstruction, a rare condition in which his bowels acted as if there were a blockage even though one was not present, parts of his intestine died and had been removed through multiple surgeries.
UCLA biochemists have achieved a first in biology: viewing at near-atomic detail the smallest protein ever seen by the technique whose development won its creators the 2017 Nobel Prize in chemistry. That technique, called cryo-electron microscopy, enables scientists to see large biomolecules, such as viruses, in extraordinary detail.
First study to show 'owls' have higher risk of mortality
Switch to daylight savings time is much harder for them
They suffer from more diseases and disorders than morning larks
Employers should allow greater flexibility in working hours
Consider abolishing daylight savings time, scientists say