Culture
The UK's definition of a 'close contact'--15 or more minutes within 2 metres of distance--used for its coronavirus track and trace system, should curb the spread of COVID-19 infection, indicates research published online in the Journal of Epidemiology & Community Health.
But this will be at the cost of having to trace many uninfected people. And its ultimate success depends on the rapid detection and isolation of the contacts traced, say the researchers.
Yale researchers have identified four drugs that may help minimize the long-term health effects of HIV infection, they report June 23 in the Journal of Clinical Investigation.
Antiretroviral therapy has proved to be a life-saving treatment for those infected with HIV. Yet even after treatment, most patients still harbor latent HIV in some immune system cells. The presence of inactive HIV in the genome can trigger chronic immune system activation, cause accelerated aging, and make patients more susceptible to cardiovascular problems and some forms of cancer.
LA JOLLA, CALIF. – June 23, 2020 – Scientists at Sanford Burnham Prebys Medical Discovery Institute have created a next-generation drug called Ciapavir (SBI-0953294) that is effective at reactivating dormant human immunodeficiency virus (HIV).
Volume 11, Issue 25 of @Oncotarget reported that Administration of landiolol hydrochloride was found to be associated with reduced incidence of atrial fibrillation after esophagectomy for esophageal cancer in our previous randomized controlled trial.
Volume 11 Issue 25 of @Oncotarget reported that this study aimed to define the mutation profile of SUM in Caucasians.
Next-generation sequencing-based genomic analysis was used to identify frequently mutated loci in 50 cancer-related genes in 31 SUM primary tumors.
The most abundant mutations in SUM were found in KIT – in 13% of cases and NRAS – also in 13%, while BRAF - only in 3% of cases.
Volume 11, Issue 25 of @Oncotarget reported that the present study was aimed at evaluating the hypothesis that p53 governs the expression and activation of the INSR gene in breast cancer cells.
BEER-SHEVA, Israel...June 23, 2020 - Could furry social robots help bolster moods and reduce pain when human to human contact isn't an option, for example, during a pandemic?
The United States is home to more than 21 million military veterans, many of whom have difficulty reintegrating into civilian life. A staggering 20 percent of them suffer from post-traumatic stress disorder (PTSD), one of the most common trauma-induced mental illnesses. Moreover, it is estimated that 20 veterans die of suicide each day, resulting in about 6,000 deaths by suicide each year.
In their model simulations, climate researchers always have to make compromises. Even with the largest computers available worldwide, they can only reproduce the real world to a limited extent. Depending on the application, simplifications have to be made in the spatial resolution, but also in the physical processes represented by the model. While model experiments over periods of months to a few years can often still be made with high spatial resolution, integrations over centuries to millennia can only be performed at coarser resolution.
Researchers from Earth and Ocean Sciences and the Ryan Institute at NUI Galway have carried out a study on the contribution of widely flushed personal care textile products (wet wipes and sanitary towels) to the ocean plastic crisis.
Why is our Universe made of matter? Why does everything exist as we know it? These questions are linked to one of the most important unsolved problems in particle physics. This problem is that of the nature of the neutrino, which could be its own antiparticle, as argued by the unfortunate Italian genius Ettore Majorana almost a century ago. If this were so, it could explain the mysterious cosmic asymmetry between matter and antimatter.
New research highlights the effect of benthic assemblages on the sulfur metabolism of coral and giant clam species. The research was conducted at CRIOBE and ENTROPIE research units, with the collaboration of the Swire institute of Marine Science of The University of Hong Kong (SWIMS, HKU), Paris-Saclay UVSQ University, The Cawthron Institute (New Zealand) and The University of French Polynesia. The findings were recently published in the journal Scientific Reports.
Researchers at the University of Seville Marine Biology Laboratory, working in the research team of Dr. José Carlos García Gómez, have demonstrated the usefulness of using the SBPQ (Sessile Bioindicators Permanent Quadrats) methodology to detect potential shifts in coastal areas.
Almost all cells of the human body present fragments of cellular proteins on their surface, so-called human leukocyte antigens or HLA peptides, which play an important role in the immune response. If the immune system detects foreign HLA peptides, such as viral peptides on a virus-infected cell or mutated peptides on a tumour cell, T-cells eliminate the corresponding cell. The entirety of the HLA peptides presented on a cell is referred to as the cell´s immunopeptidome.
New approach enables comprehensive analysis for the first time
WASHINGTON, June 23, 2020 -- When a material is subjected to an extreme load in the form of a shock or blast wave, damage often forms internally through a process called spall fracture.
Since these types of intense events are rarely isolated, research is needed to know how damaged materials respond to subsequent shock waves -- a piece of armor isn't much use if it disintegrates after one impact.