Culture
What The Study Did: Using data from completed interventional vaccine trials from 2011 to 2020, researchers examined whether racial/ethnic minority groups, females and older adults were underrepresented in U.S.-based vaccine clinical trials.
Authors: Steven A. Pergam, M.D., M.P.H., of the Fred Hutchinson Cancer Research Center in Seattle, and Julie K. Silver, M.D., of Harvard Medical School in Boston, are the corresponding authors.
Recreational hunting -- especially hunting of charismatic species for their trophies --raises ethical and moral concerns. Yet recreational hunting is frequently suggested as a way to conserve nature and support local people's livelihoods.
Despite our great progress in understanding various cellular mechanisms over the last decades, many of them remain unclear. Such is the case for exosomes, small vesicles released by cells that contain genetic materials called "RNA" and various proteins. The roles of exosomes are believed to be very varied and important, both for normal bodily functions and also in the spreading of diseases like cancer. However, exosomes are so small that studying them is challenging and calls for costly and time-consuming techniques, such as electron microscopy (EM).
At some point, microvehicles that are small enough to navigate our blood vessels will enable physicians to take biopsies, insert stents and deliver drugs with precision to sites that are difficult to reach, all from inside the body. Scientists around the world are currently researching and developing suitable microvehicles. In most cases, they are powered and controlled by acoustic and magnetic fields or using light. However, until now, propelling microvehicles against a fluid flow had proved to be a major challenge.
A research team led by Prof. QIAN Peiyuan, Head and Chair Professor from the Hong Kong University of Science and Technology (HKUST)'s Department of Ocean Science and David von Hansemann Professor of Science, has published their cutting-edge findings of symbiotic mechanisms of a deep-sea vent snail (Gigantopelta aegis) in the scientific journal Nature Communications. They discovered that Gigantopelta snail houses both sulfur-oxidizing bacteria and methane-oxidizing bacteria inside its esophageal gland cells (part of digestive system) as endosymbionts.
The latest observations from Insight-HXMT were published online in Nature Astronomy on Feb. 18. Insight-HXMT has discovered the very first X-ray burst associated with a fast radio burst (FRB) and has identified that it originated from soft-gamma repeater (SGR) J1935+2154, which is a magnetar in our Milky Way.
Before life emerged on Earth, many physicochemical processes on our planet were highly chaotic. A plethora of small compounds, and polymers of varying lengths, made up of subunits (such as the bases found in DNA and RNA), were present in every conceivable combination. Before life-like chemical processes could emerge, the level of chaos in these systems had to be reduced. In a new study, LMU physicists led by Dieter Braun show that basic features of simple polymers, together with certain aspects of the prebiotic environment, can give rise to selection processes that reduce disorder.
The major direct and indirect effects of covid-19 have forced the authorities to implement policies that strike a balance between minimizing the immediate health impact of the pandemic and containing the long-term damage to society arising from protective policies.
One parameter that is crucial for calculating how restrictive policies might be warranted is the mortality impact of covid-19, which has led to large-scale international collaborations in order to collect data that records deaths attributable to the pandemic.
Semi-trucks and other heavy-duty vehicles are responsible for nearly half of road transportation carbon dioxide emissions in Europe, according to the International Council on Clean Transportation. A team of researchers in Italy has proposed a plan to reduce the emissions without compromising priorities such as delivery times. They published their approach in IEEE/CAA Journal of Automatica Sinica, a joint publication of the IEEE and the Chinese Association of Automation.
Early Mars is considered as an environment where life could possibly have existed. There was a time in the geological history of Mars when it could have been very similar to Earth and harbored life as we know it. In opposite to the current Mars conditions, bodies of liquid water, warmer temperature, and higher atmospheric pressure could have existed in Mars' early history. Potential early forms of life on Mars should have been able to use accessible inventories of the red planet: derive energy from inorganic mineral sources and transform CO2 into biomass.
How much personal information can our phone apps gather through location tracking? To answer this question, two researchers - Mirco Musolesi (University of Bologna, Italy) and Benjamin Baron (University College London, UK) - carried out a field study using an app specifically developed for this research. Through the app employed in the study - published in Proceedings of the ACM on Interactive, Mobile, Wearable and Ubiquitous Technologies - researchers were able to identify which kind of personal information the app extracted and its privacy sensitivity according to users.
Social identity is a factor linked to wellbeing and community participation. Various studies have demonstrated the link existing between ethnic identity and empowerment and that the interaction between both of them leads to a rise in the indices of wellbeing and community participation. However, the nature of these relationships may be determined by the fact that the individual perceives his or her own group as a minority one and/or one that is subject to discrimination.
Disorders of the cells' energy supply can cause a number of serious diseases, but also seem to be connected to ageing. More research is needed on mitochondrial function to find future treatments. A new study involving researchers at Karolinska Institutet shows how an important molecule inside the mitochondria affects their function in mice and fruit flies. The study, which is published in Science Advances, adds valuable knowledge on formerly relatively unexplored protein modifications.
The mating process is one of the most important mechanisms for maintaining genetic variation in natural populations. The emergence of sexual reproduction turned out to be the most important evolutionary innovation that facilitated the evolution of eukaryotes. Paramecium is a well-known genus of ciliated protists with a complex system of 'sexes', or mating types. Paramecium reproduces asexually, by binary fission, which is not related to the mating process. During conjugation, Paramecium of compatible mating types exchange haploid nuclei, equivalent to gametes.
HSE University researchers Yuri Markov and Natalia Tyurina discovered that when people visually estimate the size of objects, they are also able to consider their distance from the observer, even if there are many such objects. The observers rely not only on the objects' retinal representation, but also on the surrounding context.