Culture

A recent genetic study at the University of Helsinki provides new information on the occurrence of a DVL2 gene defect associated with a screw tail and its relevance to canine constitution and health. The variant was found in several Bulldog and Pit Bull type breeds, and it was shown to result in caudal vertebral anomalies and shortening of the muzzle. The DLV2 variant may also affect the development of the heart.

Huntington's disease is caused by a mutation in the Huntingtin gene (HTT), which appears in adults and features motor, cognitive and psychiatric alterations. The origin of this disease has been associated with the anomalous functioning of the mutated protein: mHTT, but recent data showed the involvement of other molecular mechanisms.

DALLAS, Feb. 22, 2021 -- Twelve weeks of exercise training improved artery health and function in middle-aged and older men (ages 50-70 years) with low-to-normal testosterone levels, while testosterone therapy provided no benefits to the arteries, according to new research published today in Hypertension, an American Heart Association journal.

Stress was the most common reason teachers cited for leaving the profession before and during the pandemic, according to a RAND Corporation survey of nearly 1,000 former public-school teachers. Three of four former teachers said work was often or always stressful in the most recent year in which they taught in a public school.

In fact, teachers cited stress nearly twice as often as insufficient pay as a reason for quitting. Most former teachers went on to take jobs with less or equal pay, with 3 in 10 taking jobs with no health insurance or retirement benefits.

Young pregnant women, who appear to have fully recovered from an acute injury that reduced their kidney function, have higher rates of significant problems like preeclampsia and low birthweight babies, problems which indicate their kidneys have not actually fully recovered.

Now scientists have developed a rodent model that is enabling studies to better understand, identify and ideally avoid this recently identified association, they report in the Journal of the American Society of Nephrology.

In a world as diverse as our own, the journey towards a sustainable future will look different depending on where in the world we live, according to a recent paper published in One Earth and led by McGill University, with researchers from the Stockholm Resilience Centre.

Mitochondria are organelles that act as the powerhouses in our body. They use oxygen which we inhale and food we eat to produce energy that supports our life. This molecular activity is performed by bioenergetic nano-factories incorporated in specialized mitochondrial membranes. The nano-factories consist of proteins cooperatively transporting ions and electrons to generate chemical energy. Those have to be constantly maintained, replaced and duplicated during cell division. To address this, mitochondria have their own bioenergy protein-making machine called the mitoribosome.