Brain

Scientists have revealed the molecular mechanism regulating the trafficking of lysosomes that increases the invasiveness of radioresistant cancer cells following radiotherapy.

Radiotherapy is an effective and commonly used treatment for cancer. However, there are varieties of cancer that become resistant to these therapies, and in some cases, these radioresistant cancers can become more invasive following treatment, worsening the prognosis for the patient.

WASHINGTON -- Teens who have good, supportive relationships with their teachers enjoy better health as adults, according to research published by the American Psychological Association. Perhaps surprisingly, although friendships are important to adolescents, the study did not find the same link between good peer relationships and students' health in adulthood.

The element chromium, despite having various applications, has a bad reputation. This is because exposure to chromium compounds leads to a higher risk of respiratory cancer and other damaging effects on human health. To add to this problem, chromium also happens to be a major contributor to water pollution due to its presence in industrial waste.

In the nearly two centuries since German physician Carl Wunderlich established 98.6°F as the standard "normal" body temperature, it has been used by parents and doctors alike as the measure by which fevers -- and often the severity of illness -- have been assessed.

Because hydrogen fuel has high energy density and does not pollute the environment, it has now shown the potential to replace fossil energy. The hydrogen evolution reaction (HER) is one of the most promising hydrogen production methods as a half-reaction of the electrolysis of water. Currently, traditional Pt-based compounds are used as the most active electrocatalysts for hydrogen evolution reactions. However, Pt is relatively scarce and expensive.

WASHINGTON, October 27, 2020 -- To meet the Paris Agreement's daunting goal of preventing Earth's average temperature from rising more than 2 degrees Celsius (3.6 degrees Fahrenheit) above its level in preindustrial times, one of the best options for the energy economy will involve a shift to 100% renewable energy using solar energy and several other clean energy sources.

Individuals with autism spectrum disorder (ASD) show reduced flexible behavior on a probabilistic reversal learning task, underpinned by less optimal learning within each developmental stage, according to a study published October 27 in the open-access journal PLOS Biology by Daisy Crawley of King's College London and Lei Zhang of University of Vienna, and colleagues. As noted by the authors, these findings provide novel insights into reduced flexible behavior in relation to clinical symptoms in ASD.

Females are able to clear asymptomatic malaria infections at a faster rate than their male counterparts, says a study published today in eLife.

The findings, originally posted on the preprint server medRxiv*, suggest that biological sex-based differences are an important factor for epidemiologists to consider in the human response to malaria parasites.

DAVIS, Calif., Oct. 27, 2020 - While an infant's genes distinguish her from other newborns, a new peer-reviewed study reports that specific genes of a particular infant gut bacterium determine its symbiotic function in the infant gut. The study provides important guidance for clinicians when selecting a probiotic for use in infants to maximize impact on both short- and long-term health outcomes.

Boulder, Colo., USA: Across the western U.S., severe wildfires fueled by tinder-dry vegetation have already burned more than 3.2 million hectares (8 million acres [as of the time of this press release]) -- an area the size of Maryland -- in 2020, and nearly six times that area burned this year in Australia. And even though neither country's worst-ever fire year is not yet over, concerns are already mounting regarding the next hazard these regions will face: dangerous and destructive debris flows.

Tsukuba, Japan - In a study recently published in ACS Applied Polymer Materials, researchers from the University of Tsukaba synthesized an infrared-transmitting polymer--based on low-cost, widely available materials--that retains its shape after stretching. The properties of this polymer are highly applicable to the preparation of cheaper night-vision lenses that retain focus while imaging at variable distances.

Hydrogen is a versatile fuel that can store and release chemical energy when needed. Hydrogen can be produced in a climate-neutral way by the electrolytic splitting of water into hydrogen and oxygen using solar energy. This can be achieved photo-electrochemically (PEC), and for this approach it is necessary to have low cost photoelectrodes that provide a certain photovoltage under illumination, and remain stable in aqueous electrolytes.

Tsukuba, Japan - Effective regulation of breathing pattern is essential for many different mammalian processes such as energy production, metabolic regulation and even speech. Researchers have recently discovered that the body's production of hydrogen sulfide is important to generate a normal breathing pattern, potentially leading to new treatments for people suffering from breathing disorders such as central sleep apnea.

The lack of some genes in the BEC/TCEAL cluster could be related to some alterations associated with the autism spectrum disorder, according to a preclinical study published in the journal Genome Biology, and led by Professor Jordi Garcia Fernàndez, from the Faculty of Biology and the Institute of Biomedicine of the University of Barcelona (IBUB), and researcher Jaime Carvajal, from the Andalusian Centre for Developmental Biology - University Pablo de Olavide (CSIC-UPO).

(Boston)--Genetics and the environment (including psychiatric stress) may contribute to the pace of cellular aging, causing some individuals to have a biological age that exceeds their chronological age.