Brain

A role for prion proteins, the much debated agents of mad cow disease and vCJD, has been identified. It appears that the normal prions produced by the body help to prevent the plaques that build up in the brain to cause Alzheimer’s disease. The possible function for the mysterious proteins was discovered by a team of scientists led by Medical Research Council funded scientist Professor Nigel Hooper of the University of Leeds.

Older adults who have difficulty identifying common odors may have a greater risk of developing problems with thinking, learning and memory, according to a report in the July issue of Archives of General Psychiatry.

Differences in immune systems have been found in African Americans with multiple sclerosis (MS) compared to Caucasians, possibly offering a clue why African Americans experience more disability with MS than Caucasians, according to a study published in the July 3, 2007, issue of Neurology.

For the study, researchers compared levels of antibodies in the cerebrospinal fluid of 66 African Americans to 132 Caucasians with MS.

The study found antibody levels in the cerebrospinal fluid of African Americans with MS were 29 percent higher than levels found in affected Caucasians.

A scientific indicator of how easily distracted you are has been designed by a UCL (University College London) psychologist. It could be used as another assessment tool during the recruitment process and would have particular benefits in fields where employee distraction could lead to fatal errors.

People who are more easily distracted are at greater risk of being involved in accidents.

Fibrinogen, a blood-clotting protein found in circulating blood, has been found to inhibit the growth of central nervous system neuronal cells, a process that is necessary for the regeneration of the spinal cord after traumatic injury. The findings by researchers at the University of California, San Diego (UCSD) School of Medicine, may explain why the human body is unable to repair itself after most spinal cord injuries.

A new study by researchers at the Massachusetts General Hospital’s (MGH) Center for Mental Health and Media dispels some myths and uncovers some surprises about young teens and violent video and computer games. The study, published in the July issue of Journal of Adolescent Health, is the first to ask middle-school youth in detail about the video and computer games they play and to analyze how many of those titles are rated M (Mature – meant for ages 17 and up). It is also the first to ask children why they play video games. Some of the more striking findings include:

An overexpressed gene found at the scene of a variety of tumors is implicated in the development of two types of malignant brain cancer in a paper by researchers at The University of Texas M. D. Anderson Cancer Center to be published in the Proceedings of the National Academy of Sciences. The paper will be posted online at the PNAS web site the week of July 2.

The first baby to be created from an egg that had been matured in the laboratory, frozen, thawed and then fertilised, has been born in Canada. Three other women are pregnant by the same process. The research was presented to the 23rd annual meeting of the European Society of Human Reproduction and Embryology.

The baby girl was born to one of 20 patients with polycystic ovarian syndrome (PCOS) or with ovaries that had been detected to be polycystic by ultrasound (U/S), who took part in the trial at McGill Reproductive Center, Montreal, Canada. The baby is progressing well.

Researchers have come a step closer to understanding the incredible targeting system of human vision, namely how the brain and eye team up to spot an object in motion and follow it, a classic question of human motor control. The study shows that two distinctly different ways of seeing motion are used — one to catch up to a moving object with our eyes, a second to lock on and examine it.

Researchers at the University of Utah and elsewhere have developed a new way to predict when vegetation dries to the point it is most vulnerable to large-scale fires in the Santa Monica Mountains near Los Angeles. And this year’s forecast says the highest-risk fire period will begin July 13 – weeks earlier than usual.

Despite that, the new study also shows that unlike other areas of the western United States, global warming has not caused any apparent long-term trend toward early fire seasons in the Santa Monicas.

How precise are tests used to diagnose learning disability, progressive brain disease or impairment from head injury?

Timothy Salthouse, PhD, a noted cognitive psychologist at the University of Virginia, has demonstrated that giving a test only once isn’t enough to get a clear picture of someone’s mental functioning. It appears that repeating tests over a short period may give a more accurate range of scores, improving diagnostic workups.

Psychologists from the University of Exeter have identified an 'early warning signal' in the brain that helps us avoid repeating previous mistakes. Published in the Journal of Cognitive Neuroscience, their research identifies, for the first time, a mechanism in the brain that reacts in just 0.1 seconds to things that have resulted in us making errors in the past.

Researchers at the Salk Institute for Biological Studies have developed a novel strategy to expand the natural repertoire of 20 amino acids in mammalian cells, including neurons, and successfully inserted tailor-made amino acids into proteins in these cells. In a powerful demonstration of the method’s versatility, they then used unnatural amino acids to determine the operating mechanism of the “molecular gates” that regulate the movement of potassium ions in and out of nerve cells.

Early use of new DNA sequencing technology enables scientists to create whole genome maps of chromatin in embryonic stem cells and other cells

In what they call a “stunning research advance,” investigators at Georgetown University Medical Center have been able to use simple, non-toxic chemical injections to add and remove fat in targeted areas on the bodies of laboratory animals.

They say the discovery could revolutionize human cosmetic and reconstructive plastic surgery and treatment of diseases associated with human obesity.