Brain

Researchers have identified a gene-regulating protein in the brains of mice that triggers the animals' ability to cope with the "behavioral despair" caused by inescapable stress. They said their studies have yielded an animal model of resilience that they will use to explore how antidepressants work on the brain circuitry involved in such stress response.

Led by Eric Nestler, the researchers published their findings in the July 19, 2007, issue of the journal Neuron, published by Cell Press.

The link between alcohol and aggression is well known. What’s not so clear is just why drunks get belligerent. What is it about the brain-on-alcohol that makes fighting seem like a good idea? And do all intoxicated people get more aggressive? Or does it depend on the circumstances?

A specific genetic variation may be tied to an increased risk for severe premenstrual depression, scientists at the University of North Carolina at Chapel Hill and the National Institute of Mental Health have found.

Known medically as premenstrual dysphoric disorder, or PMDD, this psychiatric condition affects roughly 8 percent of women in their childbearing years. It's characterized by bouts of major depression and/or anxiety and severe irritability during the second half of the menstrual cycle. Symptoms subside with the onset of each menstrual period.

A research study carried out by the Universitat Autònoma de Barcelona describes the brain region connected to our declarative memory functions.

According to this experiment, part of the prefrontal cortex plays a key role in the social transmission of food preference. This research has helped learn more about how this type of memory functions. In the future, this information could be useful to find new treatment for diseases that affect the memory, such as Alzheimer's disease.

An article published today, July 16, 2007, in Proceedings of the National Academy of Sciences provides strong evidence for a novel type of communication between nerve cells in the brain. The findings may have relevance for the prevention and treatment of epilepsy, and possibly in the exploration of other aspects of brain functions, from creative thought processes to mental illnesses such as schizophrenia.

A torn anterior cruciate ligament (ACL) is among an athlete's most-dreaded injuries, often requiring surgery and months of rehab, as has been the case with Philadelphia Eagles quarterback Donovan McNabb.

While being tackled in football or hurtling into an embankment on an icy ski course can tear this major knee ligament, most athletes actually “do themselves in”--they don't collide with a person or object, they end up injuring themselves when they land off-balance during a jump or run.

But why?

Your ability to listen to a phone message in one ear while a friend is talking into your other ear—and comprehend what both are saying—is an important communication skill that’s heavily influenced by your genes, say researchers of the National Institute on Deafness and Other Communication Disorders (NIDCD), one of the National Institutes of Health.

Older women experiencing memory loss are more likely than women without cognitive decline to have problems falling asleep and staying asleep, according to a study published in the July 17, 2007, issue of Neurology®, the medical journal of the American Academy of Neurology.

For the study, 2,474 women with an average age of 69 and no signs of memory problems underwent cognitive tests over 15 years. Sleep problems were measured at the end of the study.

A fat-derived protein known for its effects on the liver and skeletal muscle might also serve as an energy-conserving signal to the brain during periods of starvation, suggests a new study.

The substance, known as adiponectin, acts on the brain to boost appetite and slow energy expenditure in an effort to maintain adequate fat stores during lean times, the researchers report.

It may seem odd to think about using metallic structures for transmitting light because light quickly attenuates on passing through a metal, but light waves travelling only a few centimeters don't lose their energy and that discover could change the face of nanotechnology.

The discovery, known as acoustic plasmon, are surface plasmons formed by the group excitation of electrons but it is produced by the interaction between light and metal surfaces.

Researchers from the University of Pittsburgh School of Medicine report a significant new advance in the search for an effective treatment for human liver cancer in the July issue of Molecular Cancer Therapeutics.

Using a newly available monoclonal antibody, they demonstrated significant reductions in tumor cell proliferation and survival in human and mouse hepatocellular cancer (HCC) cell lines. According to the researchers, this finding has significant implications not only for the treatment of liver cancer but for a number of different types of cancer.

Researchers across the world have been trying to answer the question of how RNAi works for many years. A research group headed by Prof. Renée Schroeder (MFPL) and Dr. Javier Martinez (IMBA) based at the Campus Vienna Biocenter says they have come closer to finding an answer.

Our bodies, and the biological brilliance built in, are able to move with elegance and efficiency using a combination of appropriate biomechanics, neuronal control, and adaptivity.

Simulating that with technology has so far eluded technological advances because of the motor coordination of complex multi-joint movements and the complicated nature of their dynamics.

Yet now scientists at the University of Göttingen have simulated the neuronal principles that form the dynamics of human walking in a robot.

It turns out they do.* And it can tell us a lot about learning.

In fact, "competitive fandom" is such a growing field that University of Wisconsin-Madison assistant professors Erica and Rich Halverson are spending their summer studying something they love - fantasy baseball, and why people play such games.

A new University of Colorado at Boulder study shows people have the ability to suppress emotional memories with practice, which has implications for those suffering from conditions ranging from post-traumatic stress disorder to depression.