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Childhood acute lymphoblastic leukemia (ALL) can be successfully treated using a carefully personalized chemotherapy regimen without cranial radiation, investigators at St. Jude Children's Research Hospital have found. Such radiation of the brain was once a standard ALL treatment to prevent recurrence of the leukemia in the central nervous system (CNS).

A new study by a University of Arizona professor shows employee involvement programs that executives adopt to increase efficiency also end up improving their record on diversity.

The study was published in a recent issue of the American Journal of Sociology.

According to researcher Alexandra Kalev, UA assistant professor of sociology, women and minorities are more successful and have better career opportunities when their companies offer self-directed work teams and cross-training programs.

New data show that enrollment in U.S. science and engineering (S&E) graduate programs in 2007 grew 3.3 percent over comparable data for 2006--the highest year-over-year increase since 2002 and nearly double the 1.7 percent increase seen in 2006. Science programs added the most students in absolute numbers, but engineering's percentage growth over 2006, 5.9 percent, was substantially higher than that of science, which grew by 2.4 percent. Enrollment in computer sciences programs was up 2.7 percent, the first increase since 2002.

Effective drugs for treating a chemotherapy-resistant form of lymphoma might already be on the market according to a study that has pieced together a chemical pathway involved in the disease.

By following the trail of several molecular flags that mark this type of cancer, a team from the University of California, San Diego, the Burnham Institute for Medical Research and the University of Copenhagen Hospital have discovered that anti-inflammatory drugs used to treat arthritis will shrink lymphoma tumors in mice.

La Jolla, CA, June 24, 2009 -- A team of scientists from The Scripps Research Institute, Katholeike Universiteit Leuven, and the University of Antwerp, Belgium, among other institutions, has created a genetically modified fruit fly that mimics key features of Charcot-Marie-Tooth disease, a common neurodegenerative disorder that strikes about one out of every 2,500 people in the United States.

In the mating world of yellow dung flies, large, brawny males almost always get the girl. However, a new study suggests that smaller males rule if presented with an opportunity to woo females when they are not hanging out on cow dung. It is the first time alternative male reproductive strategies have been observed in this species.

A group led by Columbia University Medical Center's Timothy Wang, M.D., has studied the role of Helicobacter infection in the development of stomach cancer and found that the hormone gastrin, which stimulates secretion of gastric acid, plays a key role in the development of Helicobacter-induced stomach cancer, and may have distinct effects on carcinogenesis in different parts of the stomach.

Researchers at the Duke University Institute for Genome Sciences & Policy have found that variation in the same gene in humans and baboons produces the same kind of disease resistance. The findings were published in the June 24 online edition of the journal Nature.

GAINESVILLE, Fla. — Almost half of kidney transplant candidates older than 60 who are put on the waiting list for a deceased-donor organ will die before getting a transplant, according to new findings from the University of Florida, Cleveland Clinic and Case Western Reserve University.

DURHAM, N.C. -- Evolutionarily speaking, baboons may be our more distant cousins among primates. But when it comes to our experiences with malaria over the course of time, it seems the stories of our two species have followed very similar plots.

LA JOLLA, CA—Experiment after experiment confirms that a diet on the brink of starvation expands lifespan in mice and many other species. But the molecular mechanism that links nutrition and survival is still poorly understood. Now, researchers at the Salk Institute for Biological Studies have identified a pivotal role for two enzymes that work together to determine the health benefits of diet restriction.

BOSTON--Dana-Farber Cancer Institute scientists' discovery of a cancer-causing gene – the first in its family to be linked to cancer – demonstrates how the panoramic view of genomics and the close-up perspective of molecular biology are needed to determine which genes are involved in cancer and which are mere bystanders. The findings are reported in the June 25 issue of the journal Nature.

La Jolla, CA, June 24, 2009 -- A team of scientists from The Scripps Research Institute, Katholeike Universiteit Leuven, and the University of Antwerp, Belgium, among other institutions, has created a genetically modified fruit fly that mimics key features of Charcot-Marie-Tooth disease, a common neurodegenerative disorder that strikes about one out of every 2,500 people in the United States.

GAINESVILLE — Researchers have identified a genetic glitch that could lead to development of neuroblastoma, a deadly form of cancer that typically strikes children under 2.

Two University of Florida scientists are part of the multicenter team of researchers that made the discovery, which could pave the way for better treatments that target the disease, according to findings published Wednesday in the journal Nature.

A two-tiered scanning-protocol for inspecting all containers at international ports could be the most affordable approach to ensuring containers moving through the global transportation system are not carrying nuclear bombs, according to a paper being presented at a services special interest group meeting of the Institute for Operations Research and the Management Sciences (INFORMS®).