Body

MAYWOOD, Il. -- If a lump is found in the breast of an adolescent girl, she often will undergo an excisional biopsy.

However, breast cancer is rare in adolescents, and the vast majority of teenage breast lumps turn out to be benign masses that are related to hormones.

A recent Loyola University Health System study published in the American Journal of Roentgenology suggests that a breast ultrasound examination might eliminate the need for biopsy in many cases.

Los Angeles, London, New Delhi, Singapore and Washington DC (June 25, 2009) – Evidence suggests that outcomes in many clinical settings leave a lot to be desired, which means that research into quality improvement (QI) in clinical care has the potential to greatly improve the lot of patients. Now a study in the journal Medical Care Research and Review published by SAGE suggests that both theoretical and practical improvements in QI effectiveness studies could make these into much more powerful tools for positive change.

ANN ARBOR, Mich. — Some patients with large tumors on their larynx can preserve their speech by opting for chemotherapy and radiation over surgery to remove the voice box.

A new study from the University of Michigan Comprehensive Cancer Center found that a single round of chemotherapy could identify those patients most likely to benefit from this approach.

When humans and animals delay reproduction because food or other resources are scarce, they may live longer to increase the impact of reproduction, according to a new study by University of Minnesota researchers published in the June 25 issue of PLoS (Public Library of Science) One.

The discovery, which explains why starvation can lead to longer life, has important implications for improving human health and lengthening lifespan.

TORONTO, ON. – Childhood physical abuse is associated with elevated rates of cancer in adulthood, according to a new study by University of Toronto researchers.

The study, to be published July 15 in the journal Cancer, shows those individuals physically abused in childhood are more likely to develop cancer than those who have not been abused. Childhood physical abuse is associated with 49 per cent higher odds of cancer in adulthood, says Esme Fuller-Thomson of U of T's Factor-Inwentash Faculty of Social Work and Department of Family and Community Medicine.

A revolutionary new protein stabilisation technique has been developed by scientists funded by the Biotechnology and Biological Sciences Research Council (BBSRC) which could lead to 30 per cent more proteins being available as potential targets for drug development - opening up exciting possibilities in drug discovery.

Researchers studying the nervous control of nematode mating behavior have produced video footage of a male worm preparing to mate with a hermaphrodite. Writing in the open access journal BMC Biology, Allyson Whittaker and Paul Sternberg from the California Institute of Technology investigated the role of the excitatory neurotransmitter acetylcholine in regulating tail muscles to achieve an exploratory embrace.

If you have hay fever, headaches or a cold, it's only a short way to the nearest chemist. The drugs, on the other hand, can take eight to ten years to develop. Until now animal experiments have been an essential step, yet they continue to raise ethical issues. "Our artificial organ systems are aimed at offering an alternative to animal experiments," says Professor Heike Mertsching of the Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB in Stuttgart. "Particularly as humans and animals have different metabolisms.

Cancer patients often suffer from severe pain that cannot be effectively treated with conventional medication. Researchers at the Pharmacology Institute of the University of Heidelberg have found the possible reasons for this – tumors release two signal substances that make nerve cells especially sensitive and enhance tumor growth. In animal tests, when the researchers blocked the effect of the signal substances on the nerve cells, the sensitivity of the nerve cells and tumor growth were reduced.

The goal of DNA barcoding is to find a simple, cheap, and rapid DNA assay that can be converted to a readily accessible technical skill that bypasses the need to rely on highly trained taxonomic specialists for identifications of the world's biota. This is driven by a desire to open taxonomic identifications to all user groups and by the short supply of taxonomists that do not even exist in many groups.

Although every cell in the body carries the genes necessary to function as an antibody-producing B cell, only a small proportion of stem cells mature into those important immune-system cells. James Hagman, PhD, Professor of Immunology at National Jewish Health and his colleagues have identified two "molecular motors" that work in opposing directions to control the development of B cells. They published their findings June 19 in the online version of The Proceedings of the National Academy of Sciences USA.

Eczema patients at risk for serious viral infections have more severe disease, are more likely to be allergic to food and other allergens, and have a frequent history of staph infections, according to researchers at National Jewish Health and other institutions in the NIH-funded Atopic Dermatitis Vaccinia Network.

Prostasin, a relatively unknown protease enzyme expressed in most epithelial cells, may play a role in the genesis of colorectal cancer. Researchers writing in the open access journal BMC Cancer have associated a reduction in the expression of inhibitors of the enzyme with malignant cellular behavior.

TORONTO, Ont., June 24, 2009 — Transferring heart attack patients to specialized hospitals to undergo angioplasty within six hours after receiving clot-busting drugs reduces the risk of life-threatening complications including repeat heart attacks, according to a new study from St. Michael's Hospital and Southlake Regional Hospital.