Body

If you were a mouse, a mere whiff of a cat, rat or snake would be enough to send you into a fearful state. Your stress hormone levels would go up and you'd begin to take extra precautions, hugging the ground as you carefully investigated your surroundings.

Now, researchers reporting in the May 14th issue of the journal Cell, a Cell Press publication, have discovered what it is that upsets the mice so. It turns out that the triggers for fear are related but species-specific urinary proteins known as Mups, which are secreted by almost every land-dwelling vertebrate.

CAMBRIDGE, Mass. (May 13, 2010) – Whitehead Institute researchers have determined a key part of how cells regulate the chromosome/microtubule interface, which is central to proper chromosomal distribution during cell division.

"This is the surveillance machinery that makes sure that the chromosomes are divided correctly between cells," says Whitehead Member Iain Cheeseman.

The findings are published in this week's issue of Molecular Cell.

BETHESDA, MD – May 13, 2010 – Genetic ancestry testing is a practice that has become increasingly popular in the U.S. over the past few years. An estimated half-million Americans will purchase genetic ancestry tests from one of the approximately 40 companies worldwide that currently provide this type of service to consumers.

Scientists at The Wistar Institute offer a new explanation for the persistent ability of melanoma cells to self-renew, one of the reasons why melanoma remains the deadliest form of skin cancer. The concept of the "dynamic stemness" of melanoma can explain why melanoma cells behave like both conventional tumor cells and cancer stem cells.

Chromosome 22q11 deletion syndrome (also known as DiGeorge syndrome) is the most common human chromosome deletion syndrome, having an estimated incidence of at least one in 4,000 live births. It has a range of severity but a multisystem impact, with symptoms that may include congenital heart defects, immunologic and endocrine abnormalities, cleft palate, gastrointestinal problems, and neuropsychiatric abnormalities.

There's no denying that people need calcium for strong, healthy bones. But new research from North Carolina State University suggests that not getting enough calcium in the earliest days of life could have a more profound, lifelong impact on bone health and perhaps even obesity than previously thought.

New findings by researchers from the Heart Institute at Intermountain Medical Center in Murray, Utah, reveals treatment of the most common heart rhythm disorder that affects more than two million Americans significantly reduces the risk of stroke, mortality, Alzheimer's disease and other forms of dementia.

CAMBRIDGE, Mass. -- Tissue engineering has long held promise for building new organs to replace damaged livers, blood vessels and other body parts. However, one major obstacle is getting cells grown in a lab dish to form 3-D shapes instead of flat layers.

Researchers at the MIT-Harvard Division of Health Sciences and Technology (HST) have come up with a new way to overcome that challenge, by encapsulating living cells in cubes and arranging them into 3-D structures, just as a child would construct buildings out of blocks.

Poor diet, too much alcohol, smoking and increasing obesity could be leading to an epidemic of oesophageal and upper stomach cancer, according to a leading UK team of specialists at The University of Nottingham and Nottingham University Hospitals.

Do nice guys finish last, or will the meek inherit the earth? A new study published in The American Naturalist suggests that, at least for birds, the right answer is somewhere in between.

Individual male birds can differ dramatically in their behavior, and this difference is often due in part to how much testosterone they produce. In many species, some males produce high testosterone and are more aggressive, while others produce lower levels and are more parental.

According to a new study by a Quebec research team, there are strong correlations between dog breeds' typical personalities, how long they live, and how much food they eat.

Vaccinating infants against rotavirus, a leading cause of severe diarrhea and dehydration among babies and young children, was associated with a dramatic decline in U.S. hospitalization rates for acute gastroenteritis. The findings appear in a study, now available online (http://www.journals.uchicago.edu/doi/abs/10.1086/652403), published in the June 1 issue of The Journal of Infectious Diseases.

Scientists in Finland have discovered that cheese can help preserve and enhance the immune system of the elderly by acting as a carrier for probiotic bacteria. The research, published in FEMS Immunology & Medical Microbiology, reveals that daily consumption of probiotic cheese helps to tackle age-related changes in the immune system.

Washington, DC – Researchers at Georgetown Lombard Comprehensive Cancer Center have been able to show, in mice, how just a little adjustment in the expression of two common genes can promote the kind of cellular changes that led to breast cancer. They say these tweaks likely mimic natural variation women have in expression of the two genes.