Great excitement greeted the discovery a few years ago that certain cells from mice and humans could be reprogrammed to become inducible pluripotent stem cells (iPS cells), as they hold promise for cell replacement therapy and modeling human disease. Two independent research groups — one led by Ludovic Vallier, at the University of Cambridge, United Kingdom, and the other led by Holger Willenbring, at the University of California San Francisco — have now shown that both possibilities are true for iPS cell–derived liver cells known as hepatocytes.
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By creating diseased liver cells from a small sample of human skin, scientists have for the first time shown that stem cells can be used to model a diverse range of inherited disorders. The University of Cambridge researchers' findings, which will hopefully lead to new treatments for those suffering from liver diseases, were published today in The Journal of Clinical Investigation.
Fire up the citronella-scented tiki torches, and slather on the DEET: Everybody knows these simple precautions repel insects, notably mosquitoes, whose bites not only itch and irritate, but also transmit diseases such as West Nile virus, malaria and dengue.
PHILADELPHIA — The American Association for Cancer Research (AACR), the world's oldest and largest cancer research organization, reiterates its support for the responsible conduct of human embryonic stem cell research that, up until this week, was funded by the National Institutes of Health (NIH) and expresses concern that the recent Federal District Court injunction to block federal funding for human embryonic stem cell research is a setback for scientific discovery.
In a real-life "back to the future" story, scientists today reported that the sustainable, environmentally-friendly process that gave birth to plywood a century ago is re-emerging as a "green" alternative to wood adhesives made from petroleum. Speaking at the 240th National Meeting of the American Chemical Society, they described development of new soy-based glues that use a substance in soy milk and tofu and could mean a new generation of more eco-friendly furniture, cabinets, flooring, and other wood products.
Electronic products pollute our environment with a number of heavy metals before, during and after they're used. In the U.S. alone, an estimated 70% of heavy metals in landfill come from discarded electronics. With flat screen TVs getting bigger and cheaper every year, environmental costs continue to mount.
BATON ROUGE – To establish a baseline for measuring and predicting the biological impact of the Deepwater Horizon oil spill, a LSU ichthyologist and an Ohio biomedical informatics researcher are using Ohio Supercomputer Center, or OSC, systems to help map data on the extent of the spill and chemicals and the distribution of various fish species.
Together with cooperation partners from the U.S., the researchers surrounding Prof. Dr. Martina Havenith (Physical Chemistry II of the RUB) describe their discovery in the Journal of the American Chemical Society (JACS).
The Wildlife Conservation Society (WCS) and the Zoological Society of London (ZSL) are requesting that the Government of Tanzania reconsider the proposed construction of a commercial road through the world's best known wildlife sanctuary—Serengeti National Park—and recommend that alternative routes be used that can meet the transportation needs of the region without disrupting the greatest remaining migration of large land animals in the world.
On receiving an honour, the American entertainer Jack Benny once said, "I don't deserve this award but I have arthritis and I don't deserve that either." Unfortunately, Benny was not alone in suffering from arthritis as he grew older. Arthritis is associated with significant discomfort and simple activities such as going for walks and climbing stairs often become extremely painful. A variety of treatments are available, usually involving a combination of drugs and physiotherapy, but these generally only address the symptoms rather than curing the condition.
NAIROBI, KENYA (26 AUGUST 2010)—As climate change intensifies drought conditions in Africa and sparks fears of a new cycle of crippling food shortages, a study released today finds widespread adoption of recently developed drought-tolerant varieties of maize could boost harvests in 13 African countries by 10 to 34 percent and generate up to US$1.5 billion in benefits for producers and consumers.
A study posted today (Wednesday, August 25) at the online site of the journal Biology of Reproduction reports that exposure of pregnant female mice to the endocrine-disrupting chemical bisphenol A may produce adverse reproductive consequences on gene expression in fetal ovaries as early as 12 hours after the mother has first been exposed to the chemical.
Bisphenol A (BPA) is a chemical used in plastics for making some baby and water bottles, linings of food and beverage cans, and other human consumer products.
JACKSONVILLE, Fla. — To their deep dismay, researchers at Mayo Clinic discovered several years ago that laboratory samples of anaplastic thyroid cancer (ATC) they were using to help them find new treatments for this lethal disease were probably some other kind of cancer.
It quickly became evident that the situation in their lab was common throughout the world. Up to half of the cell lines that were supposed to originate from patients with this rare thyroid cancer were either colon or melanoma cancer.
A short period of excess food consumption can have long term effects on your body weight and fat storage even after the initial weight is lost. A study published in BioMed Central's open access journal Nutrition & Metabolism has found that a four-week episode of increased energy intake and decreased exercise can cause increased weight and fat mass more than two years later when compared to control individuals.