Featured in the October edition of the Journal of Thoracic Oncology (JTO), data from The Tarceva Lung Cancer Survival Treatment (TRUST) confirms the safety and efficacy profile of erlotinib, a highly potent oral active, reversible inhibitor of epidermal growth factor receptor (EGFR) tyrosine-kinase (TK) activity in a large heterogeneous non-small cell lung cancer (NSCLC) population.
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Researchers from the Arkansas Epilepsy Program found treatment with rufinamide results in a significant reduction in seizure frequency compared with placebo, for patients with uncontrolled partial-onset seizures (POS). Details of this study are now available online in Epilepsia, a journal published by Wiley-Blackwell on behalf of the International League Against Epilepsy.
(Boston) – Researchers from Boston University School of Medicine (BUSM) and the VA Boston Healthcare System have conducted a study that failed to show a difference in efficacy between Bevacizumab (Avastin) and Ranibizumab (Lucentis) for the treatment of age-related macular degeneration (AMD). The study, which appears currently on-line in Eye, is believed to be the first study to describe one-year outcomes of a prospective, double-masked, randomized clinical trial directly comparing bevacizumab to ranibizuamab.
People with impaired kidney function are at a higher risk of future stroke than people with normal kidney function, concludes a study published on bmj.com today.
A second study, also published today, finds that even the earliest stages of chronic kidney disease are linked to a higher risk of coronary heart disease.
Should athletes have to undergo mandatory electrocardiographic screening (also known as ECG or heart trace) before competing? Doctors debate the issue in this week's BMJ.
Antonio Pelliccia and Domenico Corrado argue that screening athletes for "silent" heart problems would save lives. They say the best evidence of the efficacy of ECG screening on mortality in athletes comes from Italy, the only country where it is required by law, and where a mass screening programme has been in place for almost 30 years.
Early Online Releases:
1. Depression Symptoms and Low Physical Activity May Keep Dialysis Patients from WorkingEfforts to Improve Mood and Activity Might Help Patients Remain Employed
Ethnicity is a contributing risk factor of cardiovascular problems in kidney recipients of South Asian origin post-transplant, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (CJASN).
South Asians comprise 25% of all Canadian visible minorities and have a higher risk for cardiovascular disease in the general population. However, the risk of cardiovascular events has never been studied in this minority population.
TORONTO, Ont., September 30, 2010 — South Asian men and women have more than twice the risk of suffering a heart attack after a kidney transplant, according to a study led by St. Michael's nephrologist Dr. Ramesh Prasad.
Ames, Iowa - An Iowa State University researcher searched for new genes that are turned on during infection in a type of mosquito that is not only a pest, but transmits disease-causing pathogens.
A cheetah lies still in the grass. Finally, a gazelle comes into view. The cheetah plunges forward, reaches sixty-five miles per hour in three seconds, and has the hapless gazelle by the jugular in less than a minute. Then it must catch its breath, resting before eating.
Women in South Africa who underwent human papillomavirus (HPV) DNA-based testing or visual inspection of the cervix followed by treatment of test-positive women with cryotherapy had a statistically significant reduction in high grade cervical cancer precursors, compared with women in a control group, according to a study published online Sept. 30 in The Journal of the National Cancer Institute.
High in an alpine meadow, Gesine Pufal, from the University of Wellington, New Zealand, crouched low to the ground and splashed some water from her water bottle on a low green plant cushion, then sat back waiting to see if something would move. Sound crazy? Many hikers passing by her may have thought so, but Pufal was trying to find potential plant species that possess a type of plant movement called hygrochasy.
Paleontologists have unearthed the first extinct penguin with preserved evidence of scales and feathers. The 36-million-year-old fossil from Peru shows the new giant penguin's feathers were reddish brown and grey, distinct from the black tuxedoed look of living penguins.
