Body

MIAMI — Vigorous exercise of more than two hours per week reduces the risk of developing breast cancer in postmenopausal African-American women by 64 percent, compared to women of the same race who do not exercise, according to researchers at Georgetown Lombardi Comprehensive Cancer Center.

Results were presented at the Third AACR Conference on The Science of Cancer Health Disparities, held Sept. 30 to Oct. 3, 2010.

Johns Hopkins Medicine

Johns Hopkins scientists have discovered a way to turn off the immune system's allergic reaction to certain food proteins in mice, a discovery that could have implications for the millions of people who suffer severe reactions to foods, such as peanuts and milk.

The findings, published online in the journal Nature Medicine, provide hope that the body could be trained to tolerate food allergies that lead to roughly 300,000 emergency room visits and 100 to 200 deaths each year.

Reston, Va.— Research reported in the October issue of The Journal of Nuclear Medicine (JNM) shows that a molecular imaging technique may prove useful in early assessment of treatment response for cisplatin-resistant ovarian cancer.

The use of computer-aided detection (CAD) is increasing, in both screening and diagnostic mammography, according to a study in the October issue of the Journal of the American College of Radiology (www.jacr.org). CAD software systems highlight and alert the radiologist of abnormal areas of density, mass or calcification on a digitized mammographic image (of the breast) that may indicate the presence of cancer.

Researchers working in a radiology department at a mid-sized hospital were able to increase productivity and improve efficiency by developing a simple method for measuring general technologist productivity, according to a study in the October issue of the Journal of the American College of Radiology (www.jacr.org).

What does it take to save a species in the 21st century? The specter of climate change, with predicted losses to biodiversity as high as 35 percent, has some scientists and managers considering taking their conservation strategies on the road.

ROCHESTER, Minn. -- In a review article published in the October issue of Mayo Clinic Proceedings,(http://www.mayoclinicproceedings.com) Mayo Clinic physicians differentiate the ethical and legal permissibility of withholding or withdrawing life-sustaining treatments and accepted comfort measures, specifically palliative sedation, from that of physician-assisted suicide or euthanasia.

Researchers engineer adult stem cells that do not age

BUFFALO, N.Y. -- Biomedical researchers at the University at Buffalo have engineered adult stem cells that scientists can grow continuously in culture, a discovery that could speed development of cost-effective treatments for diseases including heart disease, diabetes, immune disorders and neurodegenerative diseases.

A calcium-sensing protein, STIM1, known to activate store-operated calcium channels has been found to also inhibit voltage-operated calcium channels, according to researchers at Temple University.

The researchers published their findings, The Calcium Store Sensor, STIM1, Reciprocally Controls Orai and Cav1.2 Channels, in the Oct. 1 issue of Science magazine (www.sciencemag.org).

Researchers at the National Institutes of Health have found that variations in a gene for an enzyme involved in cell energy metabolism appear to increase the risk for prostate cancer.

The genetic variations all impair the enzyme phosphodiesterase 11A (PDE11A), which helps regulate a cell's responses to hormones and other signals. Previous studies by NIH researchers have linked genetic variations that inactivate PDE11A with increased susceptibility to testicular cancer and adrenal tumors

EUGENE, OR, October 1, 2010 – A newly published study in the October 2010 issue of The Journal of the American Dental Association (JADA), conducted at New York University's College of Dentistry, confirms the safety and efficacy of a new novel method for controlling xerostomia, or dry mouth. The double masked, randomized controlled crossover study concludes that use of a unique mucoadhesive patch, affixed to the hard palate inside the mouth, provides statistically significant and sustainable improvements in salivary flow rates and subjective moistness for dry mouth sufferers.

(Boston) – Boston Medical Center (BMC) doctors have proven the reliability of the Boston Bowel Preparation Scale (BBPS), a tool that assesses the cleanliness of the colon during colonoscopies. This study, published in the October 2010 issue of the journal Gastrointestinal Endoscopy, demonstrates the scale's accuracy and could become an international standardized tool to rate colon cleanliness during colonoscopy.

Berkeley — A new study led by a University of California, Berkeley, researcher could give women a little extra motivation to visit their dentist more regularly. The study suggests that women who get dental care reduce their risk of heart attacks, stroke and other cardiovascular problems by at least one-third.

The analysis, which used data from nearly 7,000 people ages 44-88 enrolled in the Health and Retirement Study, did not find a similar benefit for men.

DARIEN, IL – A study in the Oct. 1 issue of the journal Sleep found that getting too little or too much sleep in early pregnancy is associated with elevated blood pressure in the third trimester. The study suggests that improving prenatal sleep hygiene may provide important health benefits.

For the first time to date, research published in the October edition of the Journal of Thoracic Oncology (JTO) sought to determine the use of chemotherapy in a contemporary, diverse non-small cell lung cancer (NSCLC) population encompassing all patient ages. Prior population-based studies have shown that only 20 to 30 percent of advanced lung cancer patients receive chemotherapy treatment.