Body

PHILADELPHIA (December 27, 2010) – New findings from the Monell Center reveal that weight gain of formula-fed infants is influenced by the type of formula the infant is consuming. The findings have implications related to the infant's risk for the development of obesity, diabetes and other diseases later in life.

CORVALLIS, Ore. – Researchers at Oregon State University have helped sequence the genome of a wild strawberry, laying the groundwork for genetic improvements to related fruits like apples, peaches and pears.

The advance was published today in the journal Nature Genetics.

'Food of the gods' genome sequence could make finest chocolate better

The production of high quality chocolate, and the farmers who grow it, will benefit from the recent sequencing and assembly of the chocolate tree genome, according to an international team led by Claire Lanaud of CIRAD, France, with Mark Guiltinan of Penn State, and including scientists from 18 other institutions.

Team helps decode newly sequenced strawberry genome

An international research consortium has sequenced the genome of the woodland strawberry, according to a study published in the Dec. 26 advance online edition of the journal Nature Genetics. The development is expected to unlock possibilities for breeding tastier, hardier varieties of the berry and other crops in its family.

A consortium of researchers working across five continents, including BBSRC-funded scientists in the UK, has published the genome of the wild strawberry (Fragaria vesca). The research, published today (26/12/2010) in the journal Nature Genetics will help strawberry breeders to develop disease resistance and improve fruit quality to benefit consumers.

LA JOLLA, Calif., December 23, 2010 – Melanoma is one of the least common types of skin cancer, but it is also the most deadly. Melanocytes (pigment-producing skin cells) lose the genetic regulatory mechanisms that normally limit their number, allowing them to divide and proliferate out of control. One such regulator, called MITF, controls an array of genes that influence melanocyte development, function and survival.

Phosphorous levels plummet in kidney disease patients who stick to a vegetarian diet, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (CJASN). The results suggest that eating vegetables rather than meat can help kidney disease patients avoid accumulating toxic levels of this mineral in their bodies.

use similar biochemical mechanisms to reject pollen from their own flowers as well as pollen from foreign but related plant species, thus guarding against both inbreeding and cross-species hybridization, report plant scientists at the University of California, Davis.

FINDINGS: Whitehead Institute researchers have determined that heat shock protein 90 (Hsp90) can create diverse heritable traits in brewer's yeast (Saccharomyces cerevisiae) by affecting a large portion of the yeast genome. The finding has led the researchers to conclude that Hsp90 has played a key role in shaping the evolutionary history of the yeast genome, and likely others as well.

WORCESTER, Mass. — Scientists at the University of Massachusetts Medical School and the University of Texas at Austin have uncovered evidence that environmental influences experienced by a father can be passed down to the next generation, "reprogramming" how genes function in offspring. A new study published this week in Cell shows that environmental cues—in this case, diet—influence genes in mammals from one generation to the next, evidence that until now has been sparse.

Everyone knows that exercise comes with metabolic and cardiovascular benefits, but scientists understand surprisingly little about how physical activity influences the heart itself. Now, a new study in the December 23rd issue of Cell, a Cell Press publication, offers some of the first molecular-level insights.

We aren't just what we eat; we are what our parents ate too. That's an emerging idea that is bolstered by a new study showing that mice sired by fathers fed on a low-protein diet show distinct and reproducible changes in the activity of key metabolic genes in their livers. Those changes occurred despite the fact that the fathers never saw their offspring and spent minimal time with their mothers, the researchers say, suggesting that the nutritional information is passed on to the next generation via the sperm not through some sort of social influence.

BOSTON--By tweaking a single gene, scientists have mimicked in sedentary mice the heart-strengthening effects of two weeks of endurance training, according to a report from Dana-Farber Cancer Institute and Beth Israel Deaconess Medical Center (BIDMC).

The genetic manipulation spurred the animals' heart muscle cells -- called cardiomyocytes -- to proliferate and grow larger by an amount comparable to normal mice that swam for up to three hours a day, the authors write in the journal Cell.

Use of electronic health records by hospitals across the United States has had only a limited effect on improving the quality of medical care, according to a new RAND Corporation study.

Studying a wide mix of hospitals nationally, researchers found that hospitals with basic electronic health records demonstrated a significantly higher increase in quality of care for patients being treated for heart failure.