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Researchers from Dana-Farber Cancer Institute in Boston and the Scripps Research Institute in Jupiter, Fla., report they have created prototype drugs having powerful anti-diabetic effects, yet apparently free – at least in mice – of dangerous side effects plaguing some current diabetes medications.

The researchers say that their "proof-of-principle" findings could lead to safer medications for Type 2 diabetes, which affects more than 25 million children and adults in the United States. Their findings are being published Sept. 4 in Nature .

In an article in the current issue of the journal Climatic Change Letters, Boston University researchers have estimated the impact near-term increases in global-mean temperatures will have on summertime temperatures in the U.S. and around the globe.

The "2°C global warming target" is in reference to the current international efforts to reduce emissions of heat-trapping gases and limit human-induced global-mean near-surface temperature increases to 2°C (3.5°F) relative to the pre-industrial era, three-fifths of which has already occurred.

Transplantation specialists have proposed changes to the allocation and distribution of organs used for liver transplants. The recommended policy modifications take into account the scarcity of available organs, ensuring rapid allocation and delivery of the organ to those most in need in order to reduce mortality for waitlisted patients. Details of the proposed model are available in the September issue of Liver Transplantation, a journal published by Wiley-Blackwell on behalf of the American Association for the Study of Liver Diseases.

Dana-Farber Cancer Institute scientists have successfully disrupted the function of a cancer gene involved in the formation of most human tumors by tampering with the gene's "on" switch and growth signals, rather than targeting the gene itself. The results, achieved in multiple myeloma cells, offer a promising strategy for treating not only myeloma but also many other cancer types driven by the gene MYC, the study authors say. Their findings are being published by the journal Cell on its website Sept. 1 and in its Sept. 16 print edition.

The diamondback moth, Plutella xylostella, is one of the world's most destructive crop pests. It has developed resistance to many chemical and biological pesticides, and the estimated global cost of controlling this insect is approximately US$1billion annually.

The heartbeat is the result of rhythmic contractions of the heart muscle, which are in turn regulated by electrical signals called action potentials. Action potentials result from the controlled flow of ions into heart muscle cells (depolarization) through channels in their membranes, and are followed by a compensating reverse ion current (repolarization), which restores the original state. If the duration of the repolarization phase is not just right, the risk of ventricular arrhythmia and sudden cardiac death increases significantly.

HOUSTON, Sept. 8, 2011 – A team of researchers from the University of Houston (UH) and St. Luke's Episcopal Hospital (SLEH) are working to develop improved screening methods to detect a potentially lethal, drug-resistant superbug that has made its way to Texas.

Fewer than three doses of the human papillomavirus (HPV) vaccine Cervarix may be just as effective as the standard three-dose regimen when it comes to preventive measures against cervical cancer, according to a new study published September 9 in the Journal of the National Cancer Institute.

(Baltimore, MD) – In a new study published today in the journal Developmental Science (Epub ahead of print), researchers from the Kennedy Krieger Institute and Vanderbilt University found that early motor experiences can shape infants' preferences for objects and faces. The study findings demonstrate that providing infants with "sticky mittens" to manipulate toys increases their subsequent interest in faces, suggesting advanced social development.

A possible link between what a mother eats during pregnancy and the risk of her child developing allergies has been identified in new research published in this month's The Journal of Physiology.

The research found that if a mother's diet contains a certain group of polyunsaturated fatty acids (PUFAs) – such as those found in fish, walnut oil or flaxseed – the baby's gut develops differently. The PUFAs are thought to improve how gut immune cells respond to bacteria and foreign substances, making the baby less likely to suffer from allergies.

Researchers at the University of Toronto have developed a therapy for a potentially deadly type of infection common in catheters, artificial joints and other "in-dwelling" medical devices. Their findings appear in the Open Access Journal PLoS Pathogens on September 8th.

The therapy targets fungal infections, which are hard to treat in such devices because they are composed of biofilms—complex groupings of cells that attach to surfaces. Biofilms, in turn, are coated in a gooey matrix that resists drugs.

AUSTIN, Texas—Flitting among the cool slopes of the Appalachian Mountains is a tiger swallowtail butterfly species that evolved when two other species of swallowtails hybridized long ago, a rarity in the animal world, biologists from The University of Texas at Austin and Harvard University have found.

A new, open-access article (http://bit.ly/qdTehR; DOI: 10.1603/PM10016) in the Journal of Integrated Pest Management describes the biology and ecology profiles of the soybean aphid (Aphis glycines Matsumura), an insect pest which can reduce soybean yields by $2.4 billion annually if left untreated.

Nearly 50,000 Americans are diagnosed each year with stage III orlocally advanced NSCLC, for which surgery is usually not a viabletreatment option. Optimizing nonsurgical treatment strategies for thesepatients is an ongoing research endeavor. In an article published onlineSeptember 8, 2011 in the Journal of the National Cancer Institute, RTOGresearchers report that treating patients with concurrent chemotherapyand radiation therapy significantly increased five‑year survival ratescompared with treating patients with radiation therapy upon completionof chemotherapy treatment.

The new limits on hours that physicians-in-training can work will prove costly for U.S teaching hospitals, which will need to spend up to $1.3 billion a year, and possibly more, to effect the changes, a new UCLA study suggests.

On July 1, the Accreditation Council for Graduate Medical Education (ACGME), the national body charged with overseeing the training of junior doctors as they complete their specialty training, put into effect strict duty-hour limits on interns and medical residents and instituted related changes to the training environment.