Researchers at UC Santa Cruz have determined the structure of a key part of the enzyme telomerase, which is active in most cancers and enables cancer cells to proliferate indefinitely. The new findings, published October 5 in Nature Structural & Molecular Biology, reveal how the enzyme carries out a crucial function involved in protecting the ends of chromosomes.
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Among patients with osteoarthritis of the knee, women experienced greater sensitivity to various pain modalities--such as lower tolerance to heat, cold, and pressure--and greater widespread pain than men.
The findings may be helpful for clinicians as they decide which treatments are best for different patients. Additional studies on the mechanisms involved the sex differences observed this study may also help researchers develop new treatment strategies for patients.
Research from Indiana University has found that sexual activity triggers physiological changes in the body that increase a woman's chances of getting pregnant, even outside the window of ovulation.
The results could eventually influence recommendations regarding how often to engage in sexual intercourse for couples trying to get pregnant. It could also potentially impact treatment for people with autoimmune disorders.
The conclusions are reported in papers recently published in the journal Fertility and Sterility and the journal Physiology and Behavior.
Tracked by their calls at night after heavy rains, two species of narrow-mouthed frogs have been recorded as new. During the examinations it turned out that one of the studied specimens is a hermaphrodite and another one represents the first record of the genus Cophixalus for the Misool Island.
PHILADELPHIA - The whimsically named sonic hedgehog gene, best known for controlling embryonic development, also maintains the normal physiological state and repair process of an adult healthy lung, if damaged, according to new research from the Perelman School of Medicine at the University of Pennsylvania published online this week in Nature in advance of the print edition.
Disparities in outcomes for children with retinoblastoma -- a rare eye tumor usually discovered in routine pediatric check-ups -- suggest unequal access to primary care, researchers from Dana-Farber/Boston Children's Cancer and Blood Disorders Center report in a study published in the journal JAMA Pediatrics. Although virtually all the children in the study survived, Hispanic children and children who lived in disadvantaged areas were more likely to lose an eye due to late diagnosis.
Based on measurements of radioactivity in samples of infant formula manufactured and sold around the world, researchers estimate that infants 1 year of age or younger who consume these formulas would ingest a significantly higher radioactivity dose than reported levels, but lower than internationally recommended limits.
Here's an easy way for office workers to burn a few extra calories and avoid the perils of sitting all day: stand and type.
According to a new University of Iowa study, employees with sit-stand desks stood 60 minutes more a day at work compared to their co-workers with sitting desks, and they continued to do so long after their newfangled desks lost their novelty. Plus, the sit-stand desk users walked an additional six minutes a day at work.
A new study finds that children with congenital heart disease and ADHD can take stimulant medications without fear of significant cardiovascular side effects.
When cells from the connective tissue collide, they repel one another - this phenomenon was discovered more than 50 years ago. It is only now, however, that researchers at the University of Basel have discovered the molecular basis for this process, as they report in the journal Developmental Cell. Their findings could have important implications for cancer research.
Cancer risk has been found to increase with height in both Swedish men and women, according to research presented today at the 54th Annual European Society for Paediatric Endocrinology Meeting. This long-term study is the largest carried out on the association between height and cancer in both genders.
High circulating levels of cardiovascular hormones/peptides in cancer patients are linked to shorter survival, regardless of disease type and stage of progression, reveals research published online in the journal Heart.
These chemicals, known as biomarkers, are apparent in the absence of any clinical signs of heart disease or infection, and before the start of anti-cancer treatment, some of which is known to damage heart tissue, say the researchers.
Severe asthma can have a devastating effect on sufferers, affecting their ability to work or go to school and to lead normal lives. It is difficult to treat because it is not a single disease entity. Now, for the first time, a group of European researchers has succeeded in defining three distinct types of severe asthma by analysing sputum samples from a group of patients.
Patients with advanced gastrointestinal neuroendocrine tumors (NETs) have limited treatment options and there are few oncologists who are specialized in this relatively rare disease. But now results from a multi-center randomized international trial of an innovative treatment show a marked improvement in the length of time patients with mid-gut NETs live without the disease getting worse (progression-free survival, or PFS), researchers reported to the 2015 European Cancer Congress.
Recent research suggests cooking with spices and herbs could close the 1,000 mg gap between the amount of sodium Americans consume on a daily basis, and the amount recommended by the Dietary Guidelines for Americans.