Body

Gay and bisexual men were up to six times more likely than heterosexual men to take part in indoor tanning, and twice as likely to report a history of skin cancer, including nonmelanoma and melanoma, according to a study led by UC San Francisco researchers.

Conversely, gay and bisexual women were half as likely as heterosexual women to report both indoor tanning and non-melanoma skin cancer, according to the study, led by Sarah Arron, MD, PhD, a UCSF associate professor of dermatology.

Online advertising based on Google search terms is a potentially effective way to deliver targeted cancer prevention education, according to a study led by Eleni Linos, MD, DrPH, an assistant professor of dermatology at UC San Francisco.

Indoor tanning is a preventable risk factor for skin cancer that accounts for almost half a million new malignancies per year, said Linos. "More than one in five adolescents and more than half of all college students use tanning beds, which makes them especially vulnerable," she said.

BELLINGHAM, Washington, USA, and CARDIFF, UK -- Researchers at the University of Arizona (UA) have developed a prototype of a new microscope technology that could help surgeons work with a greater degree of accuracy. The new technology, call augmented microscopy, overlays images depicting diagnostic information such as blood flow and cancerous tissue over real images of blood vessels and other tissues and structures being viewed in the microscope.

(PHILADELPHIA) - Bone marrow transplantation is a life-saving therapy for many patients with blood cancers like leukemias and lymphomas. Currently, the gold standard blood-generating stem cells are obtained from a donor, a sibling, with a perfect match to the patient in order to minimize the chance of rejection and other complications. However, not all patients will have a perfectly matched sibling. Some cancer centers have begun to explore whether half-matched donors might work just as well.

Women who have ovarian tissue removed, stored and then transplanted back to them at a later date have a good chance of successfully becoming pregnant, according to a review of the largest series of ovarian transplants performed worldwide.

Scientists have long theorized that the long neck of modern-day giraffes evolved to enable them to find more vegetation or to develop a specialized method of fighting.

A new study of fossil cervical vertebrae reveals the evolution likely occurred in several stages as one of the animal's neck vertebrae stretched first toward the head and then toward the tail a few million years later. The study's authors say the research shows, for the first time, the specifics of the evolutionary transformation in extinct species within the giraffe family.

In The BMJ this week, experts discuss the evidence and current guidelines on the controversial topic of alcohol consumption during pregnancy.

"Alcohol is not essential to the health or well being of a pregnant woman and is known to be harmful to her baby," argue Mary Mather, a retired paediatrician, and Kate Wiles, a doctoral research fellow in obstetric medicine at Guys and St Thomas NHS Trust.

They say "the only ethical advice that can be given is complete abstinence from alcohol in pregnancy."

Catching cancers when they are small still makes a difference to survival, even in the current era of more effective therapies, suggests a study of breast cancer patients in The BMJ this week.

The research team, based in the Netherlands, say that traditional factors such as tumour size and number of positive lymph nodes "still have a significant and major influence on overall mortality independent of age and tumour biology."

Over the past 40 years, deaths from bowel (colorectal) cancer have been falling in an increasing number of European countries. Yet considerable disparities still exist between men and women and between specific regions in Europe, finds a study in The BMJ this week.

Colorectal cancer is a major public health issue in most western countries. Over the past two decades, mortality has been steadily decreasing in many European countries, mainly due to a reduction in risk factors such as smoking and alcohol intake, greater participation in screening, and advances in treatments.

A study comparing preferences and willingness to pay for end-of-life treatments between advanced cancer patients and the general population of older adults has shown that patients are willing to pay more for all aspects of a good end-of-life experience compared to what healthy older adults believe they would pay if in a similar situation. Yet, both groups are willing to pay more to be free of pain and to die at home rather than for treatments that moderately extend life.

Uncle Joe smokes a pack a day, drinks like a fish and lives to a ripe old age. His brother, leading a similar lifestyle, succumbs to cancer at age 55. Why do some individuals develop certain diseases or disorders while others do not? In newly reported research that could help provide answers, scientists at Tufts University, in collaboration with the University of Florida, have developed a novel approach that uses artificial intelligence to illuminate cellular processes and suggest possible targets to correct aberrations.

Edible gifts given by male crickets to their female partners during mating contain unique proteins which could affect the females' behaviour according to research from the University of Exeter and Max Planck Institute for Chemical Ecology, published today in the journal PLOS ONE.

Caltech biologists have developed a nonsurgical method to deliver long-term contraception to both male and female animals with a single shot. The technique--so far used only in mice--holds promise as an alternative to spaying and neutering feral animals.

The approach was developed in the lab of Bruce Hay, professor of biology and biological engineering at Caltech, and is described in the October 5 issue of Current Biology. The lead author on the paper is postdoctoral scholar Juan Li.

A new study finds that rising placebo responses may play a part in the increasingly high failure rate for clinical trials of drugs designed to control chronic pain caused by nerve damage. Surprisingly, however, the analysis of clinical trials conducted since 1990 found that the increase in placebo responses occurred only in trials conducted wholly in the U.S.; trials conducted in Europe or Asia showed no changes in placebo responses over that period.