Body
Long before multiple myeloma becomes a malignant disease, the collection of immune system cells and signal carriers amid the tumor cells undergoes dramatic shifts, with alterations in both the number and type of immune cells, researchers at Dana-Farber Cancer Institute, the Broad Institute of MIT and Harvard, and Massachusetts General Hospital (MGH) report in a new study.
As the COVID-19 crisis continues to develop, researchers around the world are attempting to find the most effective treatment to combat the poorly understood virus behind this disease.
A team of researchers and patient advocates have addressed the challenges related to traveling after receiving 177Lu-DOTATATE radiation therapy in a study published in the April issue of The Journal of Nuclear Medicine. Due to the residual radiation activity of 177Lu-DOTATATE, neuroendocrine tumor patients have experienced travel delays at U.S. ports of entry. It is recommended that patients carry a travel card containing treatment information after each therapy cycle and for an additional three months after therapy has concluded to avoid travel delays.
The researchers published their findings in the prestigious journal The Lancet on World Malaria Day on 25 April even as countries the world over battle to contain transmission of the COVID-19.
The malaria trial conducted in northern Namibia demonstrates how malaria incidence can be reduced by up to 75% in settings where malaria transmission is mostly low but persistent, and plagued by sporadic outbreaks of higher numbers of malaria cases.
This scenario in Namibia is in many ways typical in neighbouring South Africa's malaria endemic districts.
New research has revealed new insights into common asthma aerosol treatments to aid the drug's future improvements which could benefit hundreds of millions of global sufferers.
Lung diseases such as asthma are a major global health burden, with an estimated 330 million asthma sufferers worldwide. The most effective treatments are through direct inhalation of medicine to the lungs. However, generating the aerosols for inhalation is a scientific challenge because of our limited knowledge of the microstructure of drug products before they are aerosolised.
Dr Sabrina Germain, a Senior Lecturer in The City Law School, says the COVID-19 pandemic could signal the end of the National Health Service based on the liberal egalitarian conception of distributive justice.
Amid the rapidly evolving global coronavirus disease 2019 (COVID-19) pandemic that has already had profound effects on public health and medical infrastructure across the globe, many questions remain about its impact on child health. New research published in the Journal of Clinical Virology indicates that the vulnerability of neonates and children and their role in the spread of the virus (severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2]) should be included in preparedness and response plans.
Skin rash combined with head and joint pain: these are the symptoms which patients with familial (hereditary) cold urticaria develop when exposed to temperatures below 15 °C. Researchers from Charité - Universitätsmedizin Berlin have discovered a new, previously unknown form of this inflammatory skin disorder. In addition to explaining why conventional treatments are ineffective in some people with the disorder, their findings also point to potential alternatives. The results of this research have been published in Nature Communications*.
PHILADELPHIA (April 27,2020) - Nursing research has an important influence on evidence-based health care practice, care delivery, and policy. Two editorials in the journal Research in Nursing & Health, by researchers at the University of Pennsylvania School of Nursing (Penn Nursing), explore how nursing research has been paramount in dealing with the emerging coronavirus pandemic.
Nursing Research is Coronavirus Research
HOUSTON -- In a first-time disclosure of IPN60090, a small-molecule inhibitor of the metabolic enzyme glutaminase (GLS1), researchers from The University of Texas MD Anderson Cancer Center's Therapeutics Discovery division and Ipsen Biopharmaceuticals reported the preclinical discovery and early-stage clinical development of this novel drug. IPN60090, now under investigation in a Phase I trial, may hold benefit for certain patients with lung and ovarian cancers.
HOUSTON - New data from the Phase III EMBRACA trial led by researchers at The University of Texas MD Anderson Cancer Center found the PARP inhibitor talazoparib did not demonstrate a statistically significant overall survival (OS) benefit for patients with metastatic HER2-negative breast cancer and mutations in the BRCA1/2 genes. Most patients included in the study went on to receive subsequent systemic therapies, which may have affected the survival outcome analysis.
Philadelphia, April 27, 2020 - Diabetic retinopathy is one of the main vascular complications of type 2 diabetes, and the most common cause of visual deterioration in adults.
A first-of-its-kind randomized clinical trial offers strong and perhaps surprising evidence that a combination of two targeted melanoma drugs when given continuously keeps patients' cancer from growing or spreading longer when compared with intermittent treatment, according to study results to be presented at the 2020 virtual annual meeting of the American Association for Cancer Research.
Bethesda, MD - Findings from a new animal study suggest that maternal nicotine exposure during breastfeeding could be linked to problems with skull and face development. Although widespread research has focused on the effects of cigarettes, little work has examined nicotine alone.
Rockville, Md. --Obesity has been shown to place physical stress on the body, but new research suggests that excess weight may also cause mental fatigue. The research, originally slated for presentation at the APS annual meeting at Experimental Biology (canceled due to the coronavirus), is published in the April issue of The FASEB Journal.