Body

PHILADELPHIA - Activating the G protein-coupled estrogen receptor (GPER) - a receptor found on the surface of many normal and cancer tissues - has been shown to stop pancreatic cancer from growing, but may also make tumors more visible to the immune system and thus more susceptible to modern immunotherapy.

COLUMBUS, Ohio - A new statement issued today by the American Heart Association emphasizes the importance of taking a multidisciplinary approach to the management of cardiovascular disease during pregnancy and outlines heart care before, during and after pregnancy.

The American College of Cardiology together with other North American cardiovascular societies has issued a framework for ethically and safely reintroducing invasive cardiovascular procedures and diagnostic tests after the initial peak of the COVID-19 pandemic. The document was published today in the Journal of the American College of Cardiology.

BOSTON - (May 1, 2020) - Excess white fat causes obesity, which in turn can drive diabetes and many other metabolic diseases that are growing at epidemic rates around the world. But all white fat is not born equal. For instance, "intra-abdominal" fat, i.e. fat within the belly, is known to carry higher risks of disease than "subcutaneous" fat that sits under the skin and often accumulates in the hips and thighs.

MADISON, Wis. -- Precision medicine has the potential to tailor treatments to a patient's unique genetic sequence. But achieving this precision -- or developing new drugs -- requires knowing which genes are involved in disease.

"Unfortunately, we don't really have a good understanding of how these genetic differences can derive differences in traits, whether that's cholesterol or obesity," says Brian Parks, a professor of nutritional sciences at the University of Wisconsin-Madison.

As the number of coronavirus cases continues to rise and the deaths mount, the American Society for Artificial Internal Organs (ASAIO) has drafted a set of recommendations for health care workers on the front lines, to help them make decisions on how to treat the most critical patients, those with severe lung or heart failure

The immune responses of a female mouse before pregnancy can predict how likely her offspring are to have behavioral deficits if the immune system is activated during pregnancy, according to researchers from the Center for Neuroscience at the University of California, Davis. The findings, published April 23 in the journal Brain, Behavior, and Immunity, could help resolve what role serious infections during pregnancy play in the later development of conditions such as autism and schizophrenia in offspring.

Washington, DC - May 4, 2020 - Korean researchers have screened 48 FDA-approved drugs against SARS-CoV-2, and found that two, that are already FDA-approved for other illnesses, seem promising. The FDA approval for other uses would greatly reduce the time needed to gain FDA approval of use in COVID-19. The research is published in Antimicrobial Agents and Chemotherapy, a journal of the American Society for Microbiology.

Many worry strenuous exercise could hurt their joints

10 years of vigorous activity did not pose risk

Strenuous activity for one to two hours weekly reduces risk of knee osteoarthritis by 30%

Osteoarthritis affects 32.5 million adults in U.S.

Prof. Viktor Seledtsov, a senior researcher at the IKBFU Center of Medical Biotechnologies and Alexei von Delwig, a researcher at Innovita Res (Vilnius, Lithuania) have published an article in Expert Review of Vaccines scientific journal. A new way to prevent autoimmune diseases associated with aging like atherosclerosis, Alzheimer's disease, and Parkinson's disease was described in the article.

Prof. Viktor Seledtsov said:

DALLAS, May 4, 2020 -- Women with cardiovascular conditions should be cared for during pregnancy by a cardio-obstetrics team or health care providers experienced in high-risk pregnancies to provide specialized maternity care for the mother and fetus, according to a new American Heart Association scientific statement, Cardiovascular Considerations in Caring for Pregnant Patients, published today in the Association's flagship journal Circulation.

New research from The George Institute for Global Health at the University of Oxford has found that there is substantial overlap in symptoms - such as chest pain - experienced by women and men upon clinical presentation, as well as crucial differences, the like of which have been established in literature for over a decade. While women had lower odds of presenting with chest pain, the study found that both sexes presented most often with this symptom.

WINSTON-SALEM, N.C. - May 4, 2020 - Intensive blood pressure control may reduce the risk of atrial fibrillation (AFib), an irregular heartbeat that can lead to serious complications such as stroke, heart failure and heart attacks, according to scientists at Wake Forest School of Medicine.

In a study published in the May 4 edition of the American Heart Association journal Hypertension, the researchers found that lowering a systolic blood pressure to less than 120 resulted in a 26% lower risk of AFib compared to systolic blood pressure of less than 140.

Obese mice with unhealthy lifestyles gain significantly less weight and avoid type 2 diabetes when they receive viruses transplanted from the stool of lean mice. These are the findings of a new University of Copenhagen study.

Boston, Mass. -- Since the World Health Organization declared COVID-19 a Public Health Concern of Global Interest on January 30, more than one million have tested positive for the illness in the United States, and more than 62,000 have died. With no FDA-approved treatments available to date, the anti-malarial drug, hydroxychloroquine, has emerged as a potential therapy for the pneumonia associated with COVID-19, with or without the antibiotic azithromycin.