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HUNTINGTON, W.Va. - New research from a team at the Marshall University Joan C. Edwards School of Medicine reveals the central role of fat cells in the systemic oxidant stress observed in renal failure-associated cardiomyopathy.

The research, published June 25 in the Journal of the American Society of Nephrology, is the first publication to demonstrate such an important role for fat cells known as adipocytes in a disease previously thought to have little involvement of such tissues.

Below please find a summary and link(s) of new coronavirus-related content published today in Annals of Internal Medicine. The summary below is not intended to substitute for the full article as a source of information. A collection of coronavirus-related content is free to the public at http://go.annals.org/coronavirus.

1. Why N95 Should Be the Standard for All COVID-19 Inpatient Care

New Rochelle, NY, June 29, 2020--Women are significantly more likely to receive prescriptions of opioid analgesics. Read the study, which was performed in a nationally representative sample of adults in the U.S., in Journal of Women's Health. Click here to read the article now.

Yale Cancer Center (YCC) scientists have found that combining the targeted drug trastuzumab with chemotherapy significantly improves survival rates for women with a rare, aggressive form of endometrial cancer. These results may help to change the standard of care worldwide for the disease. The findings are published today in the journal Clinical Cancer Research.

Researchers from the Social Cognition Center Cologne at the University of Cologne and from the University of Bremen report that participants in three experiments, each involving more than 500 adults in the United States, tended to assume the number of COVID-19 cases grew linearly with time, rather than exponentially. As a result, they underestimated actual virus growth. Interventions designed to help people avoid this bias led to an improved understanding of virus growth and increased support for social distancing measures compared with participants who did not receive such instructions.

Monday, 29 June: Research undertaken by RCSI University of Medicine and Health Sciences suggests that integrating pharmacists into general practice (GP) teams facilitates collaboration to optimise treatment plans for patients with long-term medical needs and alleviate pressures on GP practices.

The study, conducted by researchers in RCSI's Department of General Practice and School of Pharmacy and Biomolecular Sciences, is published today in BMJ Open.

A new polymeric heart valve with a life span potentially longer than current artificial valves that would also prevent the need for the millions of patients with diseased heart valves to require life-long blood thinning tablets has been developed by scientists at the universities of Bristol and Cambridge. The team's latest in-vitro results, published in Biomaterials Science, suggest that the PoliValve could last for up to 25 years.

A type of smart MRI scan used in people with heart disease could help assess whether children's cancers are especially aggressive and spot early signs that targeted treatments are working, a new study suggests.

Researchers showed that the MRI imaging technique, known as T1-mapping, could offer crucial insights into the biology of childhood cancers and give an early warning of how effective targeted treatments were likely to be.

TROY, N.Y. -- Chemically engineered peptides, designed and developed by a team of researchers at Rensselaer Polytechnic Institute, could prove valuable in the battle against some of the most persistent human health challenges.

Researchers at the University of Maryland, Baltimore County (UMBC) have developed tools to improve the analysis of functional magnetic resonance imaging (fMRI) data. Tülay Adali, professor of computer science and electrical engineering and director of UMBC's Machine Learning for Signal Processing Lab, and Qunfang Long, a Ph.D. candidate at UMBC in electrical engineering, have spearheaded groundbreaking work identifying key patterns in brain imaging for those with particular mental illnesses, such as schizophrenia. This new research is published in NeuroImage Volume 216.

LOS ANGELES -- The United States military has a constant need for service members who can serve in elite and specialized military units, such as the Marine Corps. However, because the training courses for these forces is so rigorous, the dropout rate is high.

CORVALLIS, Ore. -- A recent study evaluating the effectiveness of Oregon's occupational health monitoring system concludes that the state needs to collect and share data about workplace dangers in a more timely, relevant fashion to allow for rapid intervention.

Occupational safety and health surveillance is a type of public health surveillance that collects data on work-related fatality, injury and illness and the presence of workplace hazards. In disseminating this data, occupational health agencies aim to help workplaces implement policies and procedures to keep workers safe.

Whole genome duplication followed by massive gene loss has shaped many genomes, including the human genome. Why some gene duplicates are retained while most perish has puzzled scientists for decades.

A study, published today in Science, has found that gene retention depends on the degree of "functional and structural entanglement", which measures interdependency between gene structure and function. In other words, while most duplicates either become obsolete or they evolve new roles, some are retained forever because, evolutionarily speaking, they're simply stuck.

What The Study Did: This case series describes 20 children and adolescents who presented with new-onset acral inflammatory lesions during the COVID-19 pandemic.

Authors: Ignacio Torres-Navarro, of the Hospital Universitario y Politécnico la Fe in Valencia, Spain, is the corresponding author.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamadermatol.2020.2340)

A group of Lithuanian and Kurdish scientists have raised a hypothesis that the measles, mumps, and rubella (MMR) vaccine could protect children from COVID-19. The hypothesis is based on the discovered sequence similarity of the 30 amino acid residues between glycoproteins of SARS-CoV-2, measles and rubella viruses. An experimental analysis is required in order to support the hypothesis.

An ongoing global pandemic of coronavirus disease 2019 (COVID?19) has claimed more than 450 thousand lives already; globally, more than 9 million cases of COVID?19 infection have been confirmed.