Body
New Haven, Conn. -- Yale pharmacology professor Barbara Ehrlich and her team have uncovered a mechanism driving a rare, lethal disease called Wolfram Syndrome and also a potential treatment. Their findings appear in the July 6 edition of Proceedings of the National Academy of Sciences.
In the largest international study of its kind, researchers at the University of Alberta and Toronto's St. Michael's Hospital found that an accelerated renal-replacement therapy strategy did not reduce mortality after three months, compared to a standard strategy for critically ill patients with acute kidney injury.
New insights into Ewing sarcoma, an aggressive childhood cancer, were published July 15 in the prestigious journal Nature. Researchers from the Long School of Medicine at The University of Texas Health Science Center at San Antonio contributed to the study.
Ewing sarcoma is a bone and soft tissue cancer that primarily affects children and adolescents. The discovery, made by scientists at the University of Toronto, relates to cell structures called nucleoli and a physical change they undergo called phase separation.
ITHACA, N.Y. - Infertility affects 10% to 15% of couples globally, and while often viewed as a women's health problem, men contribute to around half of the cases.
Now, a male fertility test based on Cornell research could help predict which men might need treatment and which couples might have success with different forms of assisted reproduction.
The increased severity and mortality of SARS-CoV-2 infections in older individuals may be related to inflammageing - an age-associated phenomenon of increased general inflammation. In this Perspective, Arne Akbar and Derek Gilroy discuss this possibility as well as strategies to mitigate related effects. Inflammageing is thought to be caused, at least partially, by deterioration of aged cells (senescence) in tissues of the body that release inflammatory molecules.
Certain methods of decontaminating medical face masks for repeated use during the COVID-19 pandemic appear to damage the masks' integrity and protective function, according to research by a University of Massachusetts Amherst environmental health scientist.
July 16, 2020-- An American Thoracic Society-led international task force has released a guidance document to help guide clinicians on restoring elective in-person pulmonary and sleep services as COVID-19 incidence decreases in their communities. The new guidance, published online in the Annals of the American Thoracic Society, is titled "Restoring Pulmonary and Sleep Services as the COVID-19 Pandemic Lessens."
Kanazawa, Japan - Tens of millions of people worldwide have chronic heart failure, and only a little over half of them survive 5 years beyond their diagnosis. Now, researchers from Japan are helping doctors to assign patients into groups based on their specific needs, to improve medical outcomes.
In a study recently published in the Journal of Nuclear Cardiology, researchers from Kanazawa University have used computer science to disentangle patients most at risk of sudden arrhythmic cardiac death from patients most at risk of heart failure death.
A new peer-reviewed study by researchers at NSF International and Novateur Ventures finds significant variability in the accuracy of currently available COVID-19 antibody tests. The study, "COVID-19 Serological Tests: How Well Do They Actually Perform?", appears in the latest issue of the journal Diagnostics, an international peer-reviewed open-access journal published monthly by the Multidisciplinary Publishing Institute (MDPI).
The first case of the novel coronavirus, COVID-19, in the United States was in late January. By mid-March, "social distancing" had entered the public lexicon. People altered their routines and local jurisdictions suggested, urged, or required changes meant to slow the disease's spread.
By the end of June, however, public health officials and news outlets were talking about a second wave. In July, many states were pausing or reversing their plans to reopen while, for the second time, hospital systems worried about running out of room.
What could we have done better?
July 15, 2020 -The first consensus-based nomenclature for arterial and venous waveforms has been published online first today in Vascular Medicine (VMJ) and the Journal for Vascular Ultrasound (JVU).
Researchers at the University of Illinois at Chicago have developed a new drug that prevents blood clots without causing an increased risk of bleeding, a common side effect of all antiplatelet medications currently available.
A new study published in the journal Science Translational Medicine describes the drug and its delivery mechanisms and shows that the drug is also an effective treatment for heart attack in animal models.
Xiaoping Du, UIC professor of pharmacology and regenerative medicine at the College of Medicine, led the research.
In a new study published in Science Translational Medicine, Robert Levy, Ph.D., along with graduate student and first author Cameron Bader and colleagues, have shown that inhibiting the STING protein pathway could protect certain patients from graft versus host disease, the most serious complication from bone marrow (stem cell) transplants.
A joint report published by researchers at the Irish Longitudinal Study on Ageing (TILDA) and ALONE examines issues of loneliness and social isolation in older adults. The report offers fresh insight into the experiences of those over 70 who were advised to 'cocoon' as part of public health measures to curtail the spread of the COVID-19 virus. New data from ALONE which documents increased feelings of loneliness, anxiety and isolation in older adults throughout the pandemic, is compared with experiences of loneliness and isolation in older adults before the COVID-19 outbreak.
Creutzfeldt-Jakob disease (CJD) is a serious minority neurodegenerative disease, with an annual rate of 1.5 cases per million inhabitants, which represents approximately 11 cases each year in Catalonia. CJD is a very rapid and fatal disease, in fact, the mean life expectancy is six months after diagnosis. The characteristic symptoms are dementia and the rapid and progressive loss of motor and mental abilities.