Body
WHAT:
Kidney transplantation from deceased donors with HIV to people living with both HIV and end-stage kidney disease is feasible and safe, investigators supported by the National Institutes of Health have found. Their study demonstrates that the pool of available kidneys for people with HIV can be expanded by including donors with HIV, making more kidneys available for all who are awaiting a transplant.
CHAMPAIGN, Ill. -- Researchers have confirmed that Heartland virus, an emerging pathogen with potentially dire consequences for those infected, is present in Lone Star ticks in two Illinois counties hundreds of miles apart. Lone Star ticks were first detected in Illinois in 1999, but had not been found to be infected with Heartland virus in the state.
The findings are reported in the journal Emerging Infectious Diseases.
When drugs to kill microbes are ineffective, host-directed therapy uses the body's own immune system to deal with the infection. This approach is being tested in patients with COVID-19, and now a team of researchers at Trinity College Dublin has published a study showing how it might also work in the fight against tuberculosis (TB). The findings are published in the journal Frontiers in Immunology today (Thursday 23rd July 2020).
PREVALENCE OF CHRONIC KIDNEY DISEASE AMONG MEXICAN AMERICANS HAS DOUBLED IN RECENT YEARS
Media Contact: Michael E. Newman, mnewma25@jhmi.edu
A new study looking at nearly three decades of data from some 54,000 people has determined that the overall prevalence of chronic kidney disease (CKD) for several racial/ethnic and socioeconomic groups in the United States has stabilized in recent years, except Mexican Americans.
Responding to a need to quickly develop billions of doses of lifesaving COVID-19 vaccines, a scientific team at The University of Texas at Austin has successfully redesigned a key protein from the coronavirus, and the modification could enable much faster and more stable production of vaccines worldwide.
The new findings are described in the journal Science.
UNIVERSITY PARK, Pa. -- L-type calcium channel blockers (LCCBs) -- the most widely used drugs for treating hypertension -- may harm the heart as much as help it, according to a new study.
PHILADELPHIA -- Studies have shown that intrauterine devices (IUDs) that release progestins can help adult women with heavy menstrual bleeding, discomfort, and cramping, in addition to providing contraception. However, there are little data on whether they reduce these symptoms in younger women and adolescents, especially those with physical or intellectual disabilities. New research from the largest dataset studied to date, demonstrates that IUDs are an effective means of stopping periods or managing symptoms associated with periods in adolescents with disabilities.
DUARTE, Calif. -- Experts at City of Hope and the Translational Genomics Research Institute (TGen) are using one of the world's most comprehensive genomic analysis tools to map out personalized treatment plans for metastatic kidney cancer patients.
A research group centered around Kobe University Graduate School of Medicine's Professor YAMADA Hideto and Associate Professor TANIMURA Kenji (Department of Obstetrics and Gynecology), and Professor ARASE Hisashi et al. of Osaka University's Research Institute for Microbial Diseases (RIMD) have revealed for the first time in the world the high frequency of a novel autoantibody in women suffering from recurrent pregnancy loss. Joint research by Kobe University and Osaka University in 2015 previously discovered that this autoantibody also causes diseases such as thrombosis.
From March 2020, when COVID-19 spread throughout Europe, GPs had to rely on clinical information collected in hospitals, the only official information available, when dealing with potential infections. "However, we also heard, from colleagues or even through social media, of other and unconfirmed information that reported very different clinical pictures encountered by GPs," explains Dr Hubert Maisonneuve, a lecturer and researcher in the research group led by Professor Dagmar Haller at the Primary Care Unit of the UNIGE Faculty of Medicine, and a GP in the Lyon region.
Pancreatic cancer is a life-threatening disease with very poor survival rates in patients, and--despite various efforts--its treatment remains challenging. This is because pancreatic cancer is characterized by the presence of "fibrosis," a pathological scarring process that occurs when the physiological wound healing process goes awry. Thus, to tackle pancreatic cancer, it is crucial to understand the mechanisms driving fibrosis in detail. However, experimental models that are used to study pancreatic cancer have not yet been able to fully replicate the extent of fibrosis in human tissue.
Doctors have traditionally avoided prescribing nonsteroidal anti-inflammatory medications (NSAIDs) such as ibuprofen to patients with fractures. This belief is based on basic science research that supports delayed bone healing in some animal models, as well as in some spinal fusion cases. However, a new study from the University of Missouri School of Medicine and MU Health Care shows ibuprofen is an effective medication for fracture pain in children and its use does not affect fracture healing.
Sophia Antipolis, 23 July 2020: Eating chocolate at least once a week is linked with a reduced risk of heart disease, according to research published today in the European Journal of Preventive Cardiology, a journal of the European Society of Cardiology (ESC).1
"Our study suggests that chocolate helps keep the heart's blood vessels healthy," said study author Dr. Chayakrit Krittanawong of Baylor College of Medicine, Houston, Texas.
The cover for issue 29 of Oncotarget features Figure 5, "In vivo effects of treatment with L-Grb2 in combination with anti-angiogenic therapy in an ovarian tumor model," by Lara, et al. which reported that adaptor proteins such as growth factor receptor-bound protein-2 play important roles in cancer cell signaling.
PROVIDENCE, R.I. [Brown University] -- The epidemic of opioid-related overdose death persists across the United States, and people released from jails and prisons are at particular risk.
While the benefits of life-saving medications for opioid use disorder (MOUD) -- such as methadone, buprenorphine and extended-release (XR) naltrexone -- has been documented across hospitals and treatment centers, its uptake has been extremely limited in U.S. prisons and jail settings.